A nanostructured bacterial bioscaffold for the sustained bottom-up delivery of protein drugs.
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Antonio Villaverde | Elena García-Fruitós | Matthew J Dalby | Karl Peebo | Ursula Rinas | Ugutz Unzueta | U. Rinas | E. Vázquez | A. Villaverde | Karl Peebo | M. Dalby | P. Tsimbouri | E. Garcia-Fruitós | Joaquin Seras-Franzoso | J. Seras-Franzoso | U. Unzueta | Esther Vazquez | Penelope M Tsimbouri | José Luis Corchero | José Luis Corchero | Joaquín Seras-Franzoso
[1] Antonio Villaverde,et al. Nanostructured bacterial materials for innovative medicines. , 2010, Trends in microbiology.
[2] Vladka Gaberc-Porekar,et al. Engineering inclusion bodies for non denaturing extraction of functional proteins , 2008, Microbial cell factories.
[3] A. Villaverde,et al. Protein quality in bacterial inclusion bodies. , 2006, Trends in biotechnology.
[4] H. Cha,et al. Development of bioadhesives from marine mussels , 2008, Biotechnology journal.
[5] A. Villaverde,et al. Amyloid-like properties of bacterial inclusion bodies. , 2005, Journal of molecular biology.
[6] F. Amalric,et al. Uncoupling of cell proliferation and differentiation activities of basic fibroblast growth factor , 2000, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.
[7] A. Villaverde,et al. Protein aggregation in recombinant bacteria: biological role of inclusion bodies , 2003, Biotechnology Letters.
[8] E. Vázquez,et al. Biological activities of histidine-rich peptides; merging biotechnology and nanomedicine , 2011, Microbial cell factories.
[9] Eric Vives,et al. Cell-penetrating Peptides , 2003, The Journal of Biological Chemistry.
[10] R. Riek,et al. Amyloid as a Depot for the Formulation of Long-Acting Drugs , 2008, PLoS biology.
[11] R. Zernicke,et al. Improved bone delivery of osteoprotegerin by bisphosphonate conjugation in a rat model of osteoarthritis. , 2009, Molecular pharmaceutics.
[12] A. Fink,et al. Nativelike secondary structure in interleukin-1 beta inclusion bodies by attenuated total reflectance FTIR. , 1994, Biochemistry.
[13] Xia Zhao,et al. Induction of cell migration in vitro by an electrospun PDGF-BB/PLGA/PEG-PLA nanofibrous scaffold. , 2011, Journal of biomedical nanotechnology.
[14] Antonio Villaverde,et al. Learning about protein solubility from bacterial inclusion bodies , 2009, Microbial cell factories.
[15] R. Komel,et al. Isolation of biologically active nanomaterial (inclusion bodies) from bacterial cells , 2010, Microbial cell factories.
[16] S. Doglia,et al. In situ protein folding and activation in bacterial inclusion bodies. , 2008, Biotechnology and bioengineering.
[17] A. Villaverde,et al. Divergent genetic control of protein solubility and conformational quality in Escherichia coli. , 2007, Journal of molecular biology.
[18] U. Rinas,et al. Functional Inclusion Bodies Produced in Bacteria as Naturally Occurring Nanopills for Advanced Cell Therapies , 2012, Advanced materials.
[19] A. Villaverde,et al. Aggregation as bacterial inclusion bodies does not imply inactivation of enzymes and fluorescent proteins , 2005, Microbial cell factories.
[20] R. Komel,et al. Inclusion bodies as potential vehicles for recombinant protein delivery into epithelial cells , 2012, Microbial Cell Factories.
[21] R. Sabaté,et al. Amyloids in bacterial inclusion bodies. , 2009, Trends in biochemical sciences.
[22] A. Villaverde,et al. Co-production of GroELS discriminates between intrinsic and thermally-induced recombinant protein aggregation during substrate quality control , 2011, Microbial cell factories.
[23] J. Karp,et al. Scaffolds for Tissue Engineering , 2003 .
[24] Jae Min Lim,et al. The effect of the controlled release of nerve growth factor from collagen gel on the efficiency of neural cell culture. , 2009, Biomaterials.
[25] J. Veciana,et al. Bioadhesiveness and efficient mechanotransduction stimuli synergistically provided by bacterial inclusion bodies as scaffolds for tissue engineering. , 2012, Nanomedicine.
[26] Antonio Villaverde,et al. Unconventional microbial systems for the cost-efficient production of high-quality protein therapeutics. , 2013, Biotechnology advances.
[27] J. Veciana,et al. Surface Cell Growth Engineering Assisted by a Novel Bacterial Nanomaterial , 2009 .
[28] A. Villaverde,et al. The conformational quality of insoluble recombinant proteins is enhanced at low growth temperatures , 2007, Biotechnology and bioengineering.
[29] Zhanglin Lin,et al. Small surfactant-like peptides can drive soluble proteins into active aggregates , 2012, Microbial Cell Factories.
[30] H. Prats,et al. Nuclear Translocation of Basic Fibroblast Growth Factor a , 1991, Annals of the New York Academy of Sciences.
[31] Esther Vázquez,et al. Engineering building blocks for self-assembling protein nanoparticles , 2010, Microbial cell factories.
[32] Ana Jaklenec,et al. Sequential release of bioactive IGF-I and TGF-beta 1 from PLGA microsphere-based scaffolds. , 2008, Biomaterials.
[33] Srinivas Madduri,et al. Effect of controlled co-delivery of synergistic neurotrophic factors on early nerve regeneration in rats. , 2010, Biomaterials.
[34] A. Villaverde,et al. Role of the chaperone DnaK in protein solubility and conformational quality in inclusion body-forming Escherichia coli cells. , 2007, FEMS microbiology letters.
[35] L. Griffith,et al. The influence of tethered epidermal growth factor on connective tissue progenitor colony formation. , 2009, Biomaterials.
[36] Elena García-Fruitós,et al. Inclusion bodies: a new concept , 2010, Microbial cell factories.
[37] David Eisenberg,et al. In Brief , 2009, Nature Reviews Neuroscience.
[38] C. Werner,et al. FGF-2 and VEGF functionalization of starPEG-heparin hydrogels to modulate biomolecular and physical cues of angiogenesis. , 2010, Biomaterials.
[39] Peter Molnar,et al. Photolithographic Patterning of C2C12 Myotubes using Vitronectin as Growth Substrate in Serum‐Free Medium , 2007, Biotechnology progress.
[40] Silvia Maria Doglia,et al. Kinetics of inclusion body formation studied in intact cells by FT‐IR spectroscopy , 2005, FEBS letters.
[41] Giancarlo Tonon,et al. Structural analysis of protein inclusion bodies by Fourier transform infrared microspectroscopy. , 2006, Biochimica et biophysica acta.
[42] A. Villaverde,et al. Friendly production of bacterial inclusion bodies , 2010 .
[43] Esther Vázquez,et al. Bacterial inclusion bodies: making gold from waste. , 2012, Trends in biotechnology.
[44] Daniel B. Rifkin,et al. Fibroblast Growth Factor-2 (FGF-2) Induces Vascular Endothelial Growth Factor (VEGF) Expression in the Endothelial Cells of Forming Capillaries: An Autocrine Mechanism Contributing to Angiogenesis , 1998, The Journal of cell biology.
[45] Frank Hoffmann,et al. Minimizing inclusion body formation during recombinant protein production in Escherichia coli at bench and pilot plant scale , 2004 .
[46] R. Komel,et al. Active Protein Aggregates Produced in Escherichia coli , 2011, International journal of molecular sciences.
[47] F. Avilés,et al. Inclusion bodies: specificity in their aggregation process and amyloid-like structure. , 2008, Biochimica et biophysica acta.
[48] A. Villaverde. Nanotechnology, bionanotechnology and microbial cell factories , 2010, Microbial cell factories.
[49] A. Mitraki. Protein aggregation from inclusion bodies to amyloid and biomaterials. , 2010, Advances in protein chemistry and structural biology.
[50] E. Vázquez,et al. Post-production protein stability: trouble beyond the cell factory , 2011, Microbial cell factories.
[51] Matthew C. Phipps,et al. The effect of RGD peptides on osseointegration of hydroxyapatite biomaterials. , 2008, Biomaterials.
[52] Antonio Villaverde,et al. Recombinant protein solubility—does more mean better? , 2007, Nature Biotechnology.
[53] Ravi V Bellamkonda,et al. Differences between the effect of anisotropic and isotropic laminin and nerve growth factor presenting scaffolds on nerve regeneration across long peripheral nerve gaps. , 2008, Biomaterials.
[54] U. Rinas,et al. Packaging protein drugs as bacterial inclusion bodies for therapeutic applications , 2012, Microbial Cell Factories.
[55] Antonio Villaverde,et al. The nanoscale properties of bacterial inclusion bodies and their effect on mammalian cell proliferation. , 2010, Biomaterials.
[56] Xiaohong Li,et al. Multiple release of polyplexes of plasmids VEGF and bFGF from electrospun fibrous scaffolds towards regeneration of mature blood vessels. , 2012, Acta biomaterialia.
[57] S. Grimaldi,et al. A Combined Synthetic-Fibrin Scaffold Supports Growth and Cardiomyogenic Commitment of Human Placental Derived Stem Cells , 2012, PloS one.
[58] E. Vázquez,et al. Tunable geometry of bacterial inclusion bodies as substrate materials for tissue engineering , 2010, Nanotechnology.
[59] Ehud Gazit,et al. Amyloids: not only pathological agents but also ordered nanomaterials. , 2008, Angewandte Chemie.
[60] A. Villaverde,et al. Isolation of cell-free bacterial inclusion bodies , 2010, Microbial cell factories.
[61] A. Panda,et al. Kinetics of Inclusion Body Formation and Its Correlation with the Characteristics of Protein Aggregates in Escherichia coli , 2012, PloS one.
[62] Zhanglin Lin,et al. Active protein aggregates induced by terminally attached self-assembling peptide ELK16 in Escherichia coli , 2011, Microbial cell factories.
[63] N. Gadegaard,et al. Nanoscale surfaces for the long-term maintenance of mesenchymal stem cell phenotype and multipotency. , 2011, Nature materials.
[64] S. Sokic,et al. FGF-1 and proteolytically mediated cleavage site presentation influence three-dimensional fibroblast invasion in biomimetic PEGDA hydrogels. , 2012, Acta biomaterialia.
[65] Matthew R Chapman,et al. Functional Amyloids Signal Their Arrival , 2009, Science Signaling.
[66] Larry L Hench,et al. Third-Generation Biomedical Materials , 2002, Science.
[67] Antonio Villaverde,et al. Localization of Functional Polypeptides in Bacterial Inclusion Bodies , 2006, Applied and Environmental Microbiology.
[68] Solvig Diederichs,et al. Interplay between local versus soluble transforming growth factor-beta and fibrin scaffolds: role of cells and impact on human mesenchymal stem cell chondrogenesis. , 2012, Tissue engineering. Part A.