Evidence for the Involvement of a Pulmonary First-Pass Effect via Carboxylesterase in the Disposition of a Propranolol Ester Derivative after Intravenous Administration
暂无分享,去创建一个
T. Imai | M. Otagiri | K. Chiba | M. Hosokawa | Y. Yoshigae
[1] K. Suzuki,et al. Purification, molecular cloning, and functional expression of dog liver microsomal acyl-CoA hydrolase: a member of the carboxylesterase multigene family. , 2001, Archives of biochemistry and biophysics.
[2] P. Forkert,et al. Involvement of CYP2E1 and carboxylesterase enzymes in vinyl carbamate metabolism in human lung microsomes. , 2001, Drug metabolism and disposition: the biological fate of chemicals.
[3] A. Horita,et al. Species Differences in Stereoselective Hydrolase Activity in Intestinal Mucosa , 1998, Pharmaceutical Research.
[4] H. Clark,et al. Identification of a putative surfactant convertase in rat lung as a secreted serine carboxylesterase. , 1998, American journal of physiology. Lung cellular and molecular physiology.
[5] T. Imai,et al. Species differences in the disposition of propranolol prodrugs derived from hydrolase activity in intestinal mucosa. , 1998, Life sciences.
[6] T. Prueksaritanont,et al. Analysis of metabolite kinetics by deconvolution and in vivo-in vitro correlations of metabolite formation rates: studies of fibrinogen receptor antagonist ester prodrugs. , 1997, Journal of Pharmacy and Science.
[7] T. Imai,et al. Stereospecific activity and nature of metabolizing esterases for propranolol prodrug in hairless mouse skin, liver and plasma. , 1997, Life Science.
[8] J. Hochman,et al. Comparative studies of drug-metabolizing enzymes in dog, monkey, and human small intestines, and in Caco-2 cells. , 1996, Drug metabolism and disposition: the biological fate of chemicals.
[9] W. Bosron,et al. Tissue distribution of cocaine methyl esterase and ethyl transferase activities: correlation with carboxylesterase protein. , 1995, The Journal of pharmacology and experimental therapeutics.
[10] B. Yan,et al. Rat Serum Carboxylesterase , 1995, The Journal of Biological Chemistry.
[11] M. Brady,et al. Rat testicular carboxylesterase: cloning, cellular localization, and relationship to liver hydrolase A. , 1995, Archives of biochemistry and biophysics.
[12] D. Petersen,et al. Purification and characterization of two rat liver microsomal carboxylesterases (hydrolase A and B). , 1994, Archives of biochemistry and biophysics.
[13] B. Yan,et al. Regulation of two rat liver microsomal carboxylesterase isozymes: species differences, tissue distribution, and the effects of age, sex, and xenobiotic treatment of rats. , 1994, Archives of biochemistry and biophysics.
[14] T. Tsujita,et al. Palmitoyl-coenzyme A hydrolyzing activity in rat kidney and its relationship to carboxylesterase. , 1993, Journal of lipid research.
[15] T. Imai,et al. An In‐vitro and In‐vivo Correlative Approach to the Evaluation of Ester Prodrugs to Improve Oral Delivery of Propranolol , 1993, The Journal of pharmacy and pharmacology.
[16] P. Blain,et al. Nature and role of xenobiotic metabolizing esterases in rat liver, lung, skin and blood. , 1993, Biochemical pharmacology.
[17] Y. Masubuchi,et al. Enzymatic basis for the non-linearity of hepatic elimination of propranolol in the isolated perfused rat liver. , 1992, Biochemical pharmacology.
[18] L. V. van Zutphen,et al. The use of three ferguson-plot-based calculation methods to determine the molecular mass of proteins as illustrated by molecular mass assessment of rat-plasma carboxylesterases ES-1, ES-2, and ES-14. , 1992, Analytical biochemistry.
[19] J. Villeneuve,et al. Propranolol disposition in the rat: variation in hepatic extraction with unbound drug fraction. , 1992, Journal of pharmaceutical sciences.
[20] H. Chapman,et al. A serine esterase released by human alveolar macrophages is closely related to liver microsomal carboxylesterases. , 1991, The Journal of biological chemistry.
[21] F. Fonnum,et al. Purification and characterization of carboxylesterases from rat lung. , 1991, The Biochemical journal.
[22] M Hosokawa,et al. Characterization of molecular species of liver microsomal carboxylesterases of several animal species and humans. , 1990, Archives of biochemistry and biophysics.
[23] T. Tsujita,et al. Purification of rat kidney carboxylesterase and its comparison with other tissue esterases. , 1988, Journal of biochemistry.
[24] K. Nambu,et al. Enzymatic hydrolysis of haloperidol decanoate and its inhibition by proteins. , 1987, Biochemical pharmacology.
[25] T. Satoh,et al. Multiplicity and regulation of hepatic microsomal carboxylesterases in rats. , 1986, Molecular pharmacology.
[26] K. Iwamoto,et al. Dose‐dependent presystemic elimination of propranolol due to hepatic first‐pass metabolism in rats , 1985, The Journal of pharmacy and pharmacology.
[27] B. Corrin,et al. Propranolol uptake by dog lung: effect of pulmonary artery occlusion and shock lung. , 1982, Journal of applied physiology: respiratory, environmental and exercise physiology.
[28] R. Mentlein,et al. Simultaneous purification and comparative characterization of six serine hydrolases from rat liver microsomes. , 1980, Archives of biochemistry and biophysics.
[29] C T Dollery,et al. CONCENTRATION OF (±)‐PROPRANOLOL IN ISOLATED, PERFUSED LUNGS OF RAT , 1976, British journal of pharmacology.
[30] C. Dollery,et al. Contribution of the liver to overall elimination of propranolol , 1976, Journal of Pharmacokinetics and Biopharmaceutics.
[31] Oliver H. Lowry,et al. Protein measurement with the Folin phenol reagent. , 1951, The Journal of biological chemistry.
[32] T. Imai,et al. Characterization of esterases involved in the stereoselective hydrolysis of ester-type prodrugs of propranolol in rat liver and plasma. , 1999, Chirality.
[33] M Hosokawa,et al. The mammalian carboxylesterases: from molecules to functions. , 1998, Annual review of pharmacology and toxicology.
[34] A. Horita,et al. Species differences for stereoselective hydrolysis of propranolol prodrugs in plasma and liver. , 1997, Chirality.
[35] F. De Smet,et al. The influence of aging on the stereoselective pharmacokinetics of propranolol in the rat. , 1992, Chirality.
[36] E. Heymann. Chapter 12 – Hydrolysis of Carboxylic Esters and Amides , 1982 .
[37] E. Hodgson,et al. Reviews in biochemical toxicology , 1979 .