5‐azacitidine restores and amplifies the bicalutamide response on preclinical models of androgen receptor expressing or deficient prostate tumors
暂无分享,去创建一个
R. Pestell | E. Jannini | V. Tombolini | G. Gravina | C. Festuccia | F. Marampon | P. Bonfili | M. Di Staso | A. Vitturini | Giovanni Luca Gravina | Emmanuele A. Jannini
[1] M. Naumann,et al. Helicobacter pylori-induced activation of β-catenin involves low density lipoprotein receptor-related protein 6 and Dishevelled , 2010, Molecular Cancer.
[2] Xianglin L. Du,et al. Review of major adverse effects of androgen‐deprivation therapy in men with prostate cancer , 2009, Cancer.
[3] Vincenza Dolo,et al. Azacitidine improves antitumor effects of docetaxel and cisplatin in aggressive prostate cancer models. , 2009, Endocrine-related cancer.
[4] F. Marincola,et al. AAAS joins the Translational Medicine family , 2009, Journal of Translational Medicine.
[5] G. Bossi,et al. MEK/ERK inhibitor U0126 affects in vitro and in vivo growth of embryonal rhabdomyosarcoma , 2009, Molecular Cancer Therapeutics.
[6] D. Tindall,et al. Induction of FLIP expression by androgens protects prostate cancer cells from TRAIL‐mediated apoptosis , 2008, The Prostate.
[7] Massimo Libra,et al. Targeting prostate cancer based on signal transduction and cell cycle pathways , 2008, Cell cycle.
[8] Richard J Lee,et al. Nerve Growth factor regulation of cyclin D1 in PC12 cells through a p21RAS extracellular signal-regulated kinase pathway requires cooperative interactions between Sp1 and nuclear factor-kappaB. , 2008, Molecular biology of the cell.
[9] T. Murphy,et al. The emergence of DNA methylation as a key modulator of aberrant cell death in prostate cancer. , 2008, Endocrine-related cancer.
[10] G. Sonpavde,et al. Phase II study of azacitidine to restore responsiveness of prostate cancer to hormonal therapy. , 2007, Clinical genitourinary cancer.
[11] H. Abdulhaq,et al. The role of azacitidine in the treatment of myelodysplastic syndromes , 2007, Expert opinion on investigational drugs.
[12] Andreas Schätzlein,et al. Phase I and pharmacodynamic trial of the DNA methyltransferase inhibitor decitabine and carboplatin in solid tumors. , 2007, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[13] A. D. De Marzo,et al. Abnormal DNA methylation, epigenetics, and prostate cancer. , 2007, Frontiers in bioscience : a journal and virtual library.
[14] R. Kuefer,et al. 5-Aza-2′-Deoxycytidine Delays Androgen-Independent Disease and Improves Survival in the Transgenic Adenocarcinoma of the Mouse Prostate Mouse Model of Prostate Cancer , 2007, Clinical Cancer Research.
[15] M. Fassan,et al. Molecular genetics of prostate cancer: clinical translational opportunities. , 2007, Journal of experimental & clinical cancer research : CR.
[16] J. Issa,et al. Phase II study of low‐dose decitabine in combination with imatinib mesylate in patients with accelerated or myeloid blastic phase of chronic myelogenous leukemia , 2007, Cancer.
[17] M. Nevalainen,et al. The functional significance of nuclear receptor acetylation , 2007, Steroids.
[18] Ming Zhao,et al. Phase I Study of Decitabine-Mediated Gene Expression in Patients with Cancers Involving the Lungs, Esophagus, or Pleura , 2006, Clinical Cancer Research.
[19] C. Ciccarelli,et al. Down-regulation of c-Myc following MEK/ERK inhibition halts the expression of malignant phenotype in rhabdomyosarcoma and in non muscle-derived human tumors , 2006, Molecular Cancer.
[20] A. Dueñas-González,et al. Journal of Translational Medicine Global Dna Hypermethylation-associated Cancer Chemotherapy Resistance and Its Reversion with the Demethylating Agent Hydralazine , 2022 .
[21] Kelly B. Moran,et al. Phase I Trial of Sequential Low-Dose 5-Aza-2′-Deoxycytidine Plus High-Dose Intravenous Bolus Interleukin-2 in Patients with Melanoma or Renal Cell Carcinoma , 2006, Clinical Cancer Research.
[22] G. Glinsky. Genomic Models of Metastatic Cancer: Functional Analysis of Death-from-Cancer Signature Genes Reveals Aneuploid, Anoikis-Resistant, Metastasis-Enabling Phenotype with Altered Cell Cycle Control and Activated PcG Protein Chromatin Silencing Pathway , 2006, Cell cycle.
[23] J. Issa,et al. Phase II study of low-dose decitabine in patients with chronic myelogenous leukemia resistant to imatinib mesylate. , 2005, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[24] J. S. Rao,et al. Activation of p53/p21Waf1/Cip1 pathway by 5-aza-2'-deoxycytidine inhibits cell proliferation, induces pro-apoptotic genes and mitogen-activated protein kinases in human prostate cancer cells. , 2005, International journal of oncology.
[25] D. Tindall,et al. Letter to the Editor: Androgens and Prostate Cancer: Are the Descriptors Valid? , 2005, Cancer biology & therapy.
[26] Chenguang Wang,et al. Minireview: Cyclin D1: normal and abnormal functions. , 2004, Endocrinology.
[27] Chenguang Wang,et al. Acetylation of nuclear receptors in cellular growth and apoptosis. , 2004, Biochemical pharmacology.
[28] E. Baldi,et al. Androgen receptor: good guy or bad guy in prostate cancer invasion? , 2003, Endocrinology.
[29] P. Pohlmann,et al. Phase II Trial of Cisplatin Plus Decitabine, a New DNA Hypomethylating Agent, in Patients With Advanced Squamous Cell Carcinoma of the Cervix , 2002, American journal of clinical oncology.
[30] M. Toyota,et al. Epigenetic Regulation of Androgen Receptor Gene Expression in Human Prostate Cancers , 2000, Laboratory Investigation.
[31] J. Sludden,et al. Reversal of drug resistance in human tumor xenografts by 2'-deoxy-5-azacytidine-induced demethylation of the hMLH1 gene promoter. , 2000, Cancer research.
[32] J. Norris,et al. Intracellular Fas ligand expression causes Fas-mediated apoptosis in human prostate cancer cells resistant to monoclonal antibody-induced apoptosis. , 2000, Molecular therapy : the journal of the American Society of Gene Therapy.
[33] D. Amanatullah,et al. Cell-cycle dysregulation and the molecular mechanisms of prostate cancer. , 2000, Frontiers in bioscience : a journal and virtual library.
[34] G. Schwartsmann,et al. A Phase I Trial of Cisplatin Plus Decitabine, a New DNA-Hypomethylating Agent, in Patients with Advanced Solid Tumors and a Follow-Up Early Phase II Evaluation in Patients with Inoperable Non-Small Cell Lung Cancer , 2000, Investigational New Drugs.
[35] J. Herman,et al. Methylation of the androgen receptor promoter CpG island is associated with loss of androgen receptor expression in prostate cancer cells. , 1998, Cancer research.
[36] M. Rubin,et al. Fas ligand is constitutively secreted by prostate cancer cells in vitro. , 1998, Clinical cancer research : an official journal of the American Association for Cancer Research.
[37] G. Miller,et al. Fas‐mediated apoptosis in seven human prostate cancer cell lines: Correlation with tumor stage , 1998, The Prostate.
[38] D. Samid,et al. A Phase II Study of 5-AZA-2'Deoxycytidine (Decitabine) in Hormone Independent Metastatic (D2) Prostate Cancer , 1998, Tumori.
[39] A. Belldegrun,et al. Immunosensitization of prostate carcinoma cell lines for lymphocytes (CTL, TIL, LAK)-mediated apoptosis via the Fas-Fas-ligand pathway of cytotoxicity. , 1997, Cellular immunology.
[40] A. Belldegrun,et al. Chemosensitization of human prostate carcinoma cell lines to anti-fas-mediated cytotoxicity and apoptosis. , 1997, Clinical cancer research : an official journal of the American Association for Cancer Research.
[41] M. Cohen,et al. Fas-mediated apoptosis in human prostatic carcinoma cell lines. , 1997, Cancer research.
[42] M. van Glabbeke,et al. The EORTC Early Clinical Trials Cooperative Group experience with 5-aza-2'-deoxycytidine (NSC 127716) in patients with colo-rectal, head and neck, renal carcinomas and malignant melanomas. , 1987, European journal of cancer & clinical oncology.
[43] E. Ricevuto,et al. Downmodulation of dimethyl transferase activity enhances tumor necrosis factor-related apoptosis-inducing ligand-induced apoptosis in prostate cancer cells. , 2008, International Journal of Oncology.
[44] Stephanie Daignault,et al. Inhibition of DNA methyltransferase activity prevents tumorigenesis in a mouse model of prostate cancer. , 2006, Cancer research.
[45] M. Peter,et al. The CD95(APO-1/Fas) DISC and beyond , 2003, Cell Death and Differentiation.
[46] R. Willemze,et al. A randomized phase II study on the effects of 5-Aza-2'-deoxycytidine combined with either amsacrine or idarubicin in patients with relapsed acute leukemia: an EORTC Leukemia Cooperative Group phase II study (06893). , 1997, Leukemia.