PROPELLER EPI: An MRI technique suitable for diffusion tensor imaging at high field strength with reduced geometric distortions

A technique suitable for diffusion tensor imaging (DTI) at high field strengths is presented in this work. The method is based on a periodically rotated overlapping parallel lines with enhanced reconstruction (PROPELLER) k‐space trajectory using EPI as the signal readout module, and hence is dubbed PROPELLER EPI. The implementation of PROPELLER EPI included a series of correction schemes to reduce possible errors associated with the intrinsically higher sensitivity of EPI to off‐resonance effects. Experimental results on a 3.0 Tesla MR system showed that the PROPELLER EPI images exhibit substantially reduced geometric distortions compared with single‐shot EPI, at a much lower RF specific absorption rate (SAR) than the original version of the PROPELLER fast spin‐echo (FSE) technique. For DTI, the self‐navigated phase‐correction capability of the PROPELLER EPI sequence was shown to be effective for in vivo imaging. A higher signal‐to‐noise ratio (SNR) compared to single‐shot EPI at an identical total scan time was achieved, which is advantageous for routine DTI applications in clinical practice. Magn Reson Med, 2005. © 2005 Wiley‐Liss, Inc.

[1]  Derek K. Jones,et al.  Determining and visualizing uncertainty in estimates of fiber orientation from diffusion tensor MRI , 2003, Magnetic resonance in medicine.

[2]  P. Basser,et al.  In vivo fiber tractography using DT‐MRI data , 2000, Magnetic resonance in medicine.

[3]  X. Hu,et al.  Fast interleaved echo‐planar imaging with navigator: High resolution anatomic and functional images at 4 tesla , 1996, Magnetic resonance in medicine.

[4]  R. Ito,et al.  Diffusion tensor brain MR imaging in X-linked cerebral adrenoleukodystrophy , 2001, Neurology.

[5]  K. Arfanakis,et al.  k‐space undersampling in PROPELLER imaging , 2005, Magnetic resonance in medicine.

[6]  Gaohong Wu,et al.  Multiecho segmented EPI with z‐shimmed background gradient compensation (MESBAC) pulse sequence for fMRI , 2002, Magnetic resonance in medicine.

[7]  C Thomsen,et al.  High-resolution diffusion imaging using phase-corrected segmented echo-planar imaging. , 2000, Magnetic resonance imaging.

[8]  P. Lauterbur,et al.  Image Formation by Induced Local Interactions: Examples Employing Nuclear Magnetic Resonance , 1973, Nature.

[9]  J. Pipe Motion correction with PROPELLER MRI: Application to head motion and free‐breathing cardiac imaging , 1999, Magnetic resonance in medicine.

[10]  P. Basser,et al.  Statistical artifacts in diffusion tensor MRI (DT‐MRI) caused by background noise , 2000, Magnetic resonance in medicine.

[11]  N. Chen,et al.  Optimized distortion correction technique for echo planar imaging , 2001, Magnetic resonance in medicine.

[12]  James G Pipe,et al.  Multishot diffusion‐weighted FSE using PROPELLER MRI , 2002, Magnetic resonance in medicine.

[13]  K. Kwong,et al.  Propeller EPI with SENSE parallel imaging using a circularly symmetric phase array RF coil , 2002 .

[14]  M. Kraut,et al.  Comparison of weakness progression in inclusion body myositis during treatment with methotrexate or placebo , 2002, Annals of neurology.

[15]  M. O’Donnell,et al.  POTENTIAL PROBLEMS WITH SELECTIVE PULSES IN NMR IMAGING SYSTEMS , 1984, Medical physics.

[16]  V. Haughton,et al.  Diffusion tensor MR imaging in diffuse axonal injury. , 2002, AJNR. American journal of neuroradiology.

[17]  James G Pipe,et al.  Brain imaging in the unsedated pediatric patient: comparison of periodically rotated overlapping parallel lines with enhanced reconstruction and single-shot fast spin-echo sequences. , 2003, AJNR. American journal of neuroradiology.

[18]  James M Provenzale,et al.  Multiple sclerosis: diffusion tensor MR imaging for evaluation of normal-appearing white matter. , 2002, Radiology.

[19]  Xavier Golay,et al.  Reduction of magnetic field inhomogeneity artifacts in echo planar imaging with SENSE and GESEPI at high field , 2004, Magnetic resonance in medicine.

[20]  G. Mckinnon Ultrafast interleaved gradient‐echo‐planar imaging on a standard scanner , 1993, Magnetic resonance in medicine.

[21]  P. Matthews,et al.  White matter and lesion T1 relaxation times increase in parallel and correlate with disability in multiple sclerosis , 2002, Journal of Neurology.

[22]  Hangyi Jiang,et al.  Origin and minimization of residual motion‐related artifacts in navigator‐corrected segmented diffusion‐weighted EPI of the human brain , 2002, Magnetic resonance in medicine.

[23]  S. Sourbron,et al.  Study of pediatric brain development using magnetic resonance imaging of anisotropic diffusion. , 2002, Magnetic resonance imaging.

[24]  J. Pipe,et al.  Improved image quality and detection of acute cerebral infarction with PROPELLER diffusion-weighted MR imaging. , 2002, Radiology.

[25]  P. V. van Zijl,et al.  Three‐dimensional tracking of axonal projections in the brain by magnetic resonance imaging , 1999, Annals of neurology.