Molecular architecture and assembly of the DDB1–CUL4A ubiquitin ligase machinery

[1]  P. Zhou,et al.  UV-damaged DNA-binding Proteins Are Targets of CUL-4A-mediated Ubiquitination and Degradation* , 2001, The Journal of Biological Chemistry.

[2]  Hengbin Wang,et al.  Histone H3 and H4 ubiquitylation by the CUL4-DDB-ROC1 ubiquitin ligase facilitates cellular response to DNA damage. , 2006, Molecular cell.

[3]  A. Carr,et al.  Transactivation of Schizosaccharomyces pombe cdt2+ stimulates a Pcu4–Ddb1–CSN ubiquitin ligase , 2005, The EMBO journal.

[4]  Jianyu Zheng,et al.  Radiation-mediated proteolysis of CDT1 by CUL4–ROC1 and CSN complexes constitutes a new checkpoint , 2003, Nature Cell Biology.

[5]  M. Kapetanaki,et al.  The DDB1-CUL4ADDB2 ubiquitin ligase is deficient in xeroderma pigmentosum group E and targets histone H2A at UV-damaged DNA sites. , 2006, Proceedings of the National Academy of Sciences of the United States of America.

[6]  Keiji Tanaka,et al.  UV-Induced Ubiquitylation of XPC Protein Mediated by UV-DDB-Ubiquitin Ligase Complex , 2005, Cell.

[7]  P. Raychaudhuri,et al.  The Xeroderma Pigmentosum Group E Gene Product DDB2 Is a Specific Target of Cullin 4A in Mammalian Cells , 2001, Molecular and Cellular Biology.

[8]  Stuart Linn,et al.  The Naturally Occurring Mutants of DDB Are Impaired in Stimulating Nuclear Import of the p125 Subunit and E2F1-Activated Transcription , 1999, Molecular and Cellular Biology.

[9]  Jun-ichi Sawada,et al.  The Ubiquitin Ligase Activity in the DDB2 and CSA Complexes Is Differentially Regulated by the COP9 Signalosome in Response to DNA Damage , 2003, Cell.

[10]  C. Pickart,et al.  Mechanisms underlying ubiquitination. , 2001, Annual review of biochemistry.

[11]  C. Horvath.  Weapons of STAT destruction. Interferon evasion by paramyxovirus V protein. , 2004, European journal of biochemistry.

[12]  R. Martienssen,et al.  Two Novel Proteins, Dos1 and Dos2, Interact with Rik1 to Regulate Heterochromatic RNA Interference and Histone Modification , 2005, Current Biology.

[13]  N. Zheng,et al.  Structure of DDB1 in Complex with a Paramyxovirus V Protein: Viral Hijack of a Propeller Cluster in Ubiquitin Ligase , 2006, Cell.

[14]  K. A. Powell,et al.  Cop9/signalosome subunits and Pcu4 regulate ribonucleotide reductase by both checkpoint-dependent and -independent mechanisms. , 2003, Genes & development.

[15]  M. MacCoss,et al.  The KLHL12–Cullin-3 ubiquitin ligase negatively regulates the Wnt–β-catenin pathway by targeting Dishevelled for degradation , 2006, Nature Cell Biology.

[16]  C. McCall,et al.  Targeted ubiquitination of CDT1 by the DDB1–CUL4A–ROC1 ligase in response to DNA damage , 2004, Nature Cell Biology.

[17]  S. Sprang,et al.  The structure of the G protein heterotrimer Giα1 β 1 γ 2 , 1995, Cell.

[18]  A. Harel-Bellan,et al.  CSA-dependent degradation of CSB by the ubiquitin-proteasome pathway establishes a link between complementation factors of the Cockayne syndrome. , 2006, Genes & development.

[19]  G. Singh,et al.  The Clr7 and Clr8 Directionality Factors and the Pcu4 Cullin Mediate Heterochromatin Formation in the Fission Yeast Schizosaccharomyces pombe , 2005, Genetics.

[20]  Raymond J. Deshaies,et al.  Function and regulation of cullin–RING ubiquitin ligases , 2005, Nature Reviews Molecular Cell Biology.

[21]  P. Raychaudhuri,et al.  Ddb1 Is Required for the Proteolysis of the Schizosaccharomyces pombe Replication Inhibitor Spd1 during S Phase and after DNA Damage* , 2004, Journal of Biological Chemistry.

[22]  C. Horvath.  Weapons of STAT destruction , 2004 .

[23]  R. Deshaies,et al.  Human De-Etiolated-1 Regulates c-Jun by Assembling a CUL4A Ubiquitin Ligase , 2004, Science.

[24]  S. Elledge,et al.  Structure of the Cul1–Rbx1–Skp1–F boxSkp2 SCF ubiquitin ligase complex , 2002, Nature.

[25]  H. Hamm,et al.  The 2.0 Å crystal structure of a heterotrimeric G protein , 1996, Nature.

[26]  S. Bontron,et al.  Hepatitis B Virus X Protein and Simian Virus 5 V Protein Exhibit Similar UV-DDB1 Binding Properties To Mediate Distinct Activities , 2003, Journal of Virology.