The increasing recreational use of nitrous oxide: history revisited.

of insulin-resistant and insulin-sensitive obesity. J Clin Endocrinol Metab 2015; 100: 4082–91 24. Coutinho T, Goel K, Correa de Sa D, et al. Central obesity and survival in subjects with coronary artery disease: a systematic review of the literature and collaborative analysis with individual subject data. J Am Coll Cardiol 2011; 57: 1877–86 25. Dutton DJ, McLaren L. The usefulness of ‘corrected’ body mass index vs. self-reported body mass index: comparing the population distributions, sensitivity, specificity, and predictive utility of three correction equations using Canadian population-based data. BMC Public Health 2014; 14: 430 26. Yusuf S, Hawken S, Ounpuu S, et al. Obesity and the risk of myocardial infarction in 27,000 participants from 52 countries: a case-control study. Lancet 2005; 366: 1640–9 27. CoutinhoT, Goel K, Correa de SaD, et al. Combining bodymass index with measures of central obesity in the assessment of mortality in subjects with coronary disease: role of ‘normal weight central obesity’. J Am Coll Cardiol 2013; 61: 553–60 28. Peixoto Mdo R, Benicio MH, Latorre Mdo R, Jardim PC. Waist circumference and body mass index as predictors of hypertension. Arq Bras Cardiol 2006; 87: 462–70 29. Tanamas SK, LeanME, Combet E, Vlassopoulos A, Zimmet PZ, Peeters A. Changing guards: time to move beyond body mass index for population monitoring of excess adiposity. QJM Advance Access published on November 1, 2015, doi: 10.1093/ qjmed/hcv201 30. Tsukada K, Miyazaki T, Kato H, et al. Body fat accumulation and postoperative complications after abdominal surgery. Am Surg 2004; 70: 347–51 31. Kartheuser AH, Leonard DF, Penninckx F, et al. Waist circumference and waist/hip ratio are better predictive risk factors for mortality and morbidity after colorectal surgery than body mass index and body surface area. Ann Surg 2013; 258: 722–30 32. Ozhan H, Alemdar R, Caglar O, et al. Performance of bioelectrical impedance analysis in the diagnosis of metabolic syndrome. J Investig Med 2012; 60: 587–91 33. Wang H, Chen YE, Eitzman DT. Imaging body fat: techniques and cardiometabolic implications. Arterioscler Thromb Vasc Biol 2014; 34: 2217–23 34. Bays H. Central obesity as a clinical marker of adiposopathy; increased visceral adiposity as a surrogate marker for global fat dysfunction. Curr Opin Endocrinol Diabetes Obes 2014; 21: 345–51 35. Pouliot MC, Despres JP, Lemieux S, et al. Waist circumference and abdominal sagittal diameter: best simple anthropometric indexes of abdominal visceral adipose tissue accumulation and related cardiovascular risk in men and women. Am J Cardiol 1994; 73: 460–8 36. Seidell JC, Perusse L, Despres JP, Bouchard C. Waist and hip circumferences have independent and opposite effects on cardiovascular disease risk factors: the Quebec Family Study. Am J Clin Nutr 2001; 74: 315–21

[1]  Parliamentary Counsel Psychoactive Substances Bill , 2015 .

[2]  Jiunn‐Tay Lee,et al.  Recreational Nitrous Oxide Abuse-Induced Vitamin B12 Deficiency in a Patient Presenting with Hyperpigmentation of the Skin , 2013, Case Reports in Dermatology.

[3]  R. Hoffman,et al.  Severe myeloneuropathy from acute high-dose nitrous oxide (N2O) abuse. , 2011, The Journal of emergency medicine.

[4]  Yang-Chyuan Chang,et al.  Subacute combined degeneration caused by nitrous oxide intoxication: case reports. , 2011, Acta neurologica Taiwanica.

[5]  H. Davy Researches, Chemical and Philosophical, Chiefly Concerning Nitrous Oxide, or Dephlogisticated Nitrous Air, and Its Respiration. , 2009 .

[6]  M. Jay Nitrous oxide: recreational use, regulation and harm reduction , 2008 .

[7]  Deepak Sharma,et al.  A Survey on Use of Nitrous Oxide in Current Anaesthetic Practice in India , 2007 .

[8]  J. Hall,et al.  The use of nitrous oxide in anaesthetic practice: a questionnaire survey , 2002, Anaesthesia.

[9]  R. Edlich,et al.  Frostbite of the face after recreational misuse of nitrous oxide. , 1996, Burns.

[10]  A. Lloyd,et al.  Asphyxial deaths from the recreational use of nitrous oxide. , 1992, Journal of forensic sciences.

[11]  W. A. Jack General anaesthesia sedation and resuscitation in dentistry' , 1992, British Dental Journal.

[12]  D. W. James General anaesthesia, sedation and resuscitation in dentistry , 1991, British Dental Journal.

[13]  E. Mehr Basic Physics and Measurement in Anaesthesia , 1991 .

[14]  J. LiPuma,et al.  Nitrous oxide abuse: a new cause of pneumomediastinum. , 1982, Radiology.

[15]  G. Kenny,et al.  Basic physics and measurement in anaesthesia , 1982 .

[16]  R. Layzer MYELONEUROPATHY AFTER PROLONGED EXPOSURE TO NITROUS OXIDE , 1978, The Lancet.

[17]  J. Clutton-Brock Two cases of poisoning by contamination of nitrous oxide with higher oxides of nitrogen during anaesthesia. , 1967, British journal of anaesthesia.

[18]  T. Peck,et al.  Pharmacology for Anaesthesia and Intensive Care: General anaesthetic agents , 2008 .

[19]  J. Ritter,et al.  General Anaesthetic Agents , 2007, Pharmacology for Anaesthesia and Intensive Care.

[20]  Higher oxides of nitrogen as an impurity in nitrous oxide. , 1967, British journal of anaesthesia.