Interaction between valproic acid and carbapenems: Case series and literature review

[1]  Thaddaus R. Hellwig,et al.  Potential interaction between valproic acid and doripenem. , 2011, Current drug safety.

[2]  Chi-Yu Chen,et al.  Decrease in serum valproic acid levels during treatment with ertapenem. , 2010, American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists.

[3]  B. Gidal,et al.  The Effect of Carbapenem Antibiotics on Plasma Concentrations of Valproic Acid , 2009, The Annals of pharmacotherapy.

[4]  A. Hoffman,et al.  Valproic Acid Plasma Concentration Decreases in a Dose‐Independent Manner Following Administration of Meropenem: A Retrospective Study , 2009, Journal of clinical pharmacology.

[5]  Jie Gu,et al.  Effect of concomitant administration of meropenem and valproic acid in an elderly Chinese patient. , 2009, The American journal of geriatric pharmacotherapy.

[6]  S. Kick,et al.  Valproic Acid-Carbapenem Interaction: Report of Six Cases and a Review of the Literature , 2009, Drug metabolism and drug interactions.

[7]  Jeong-Ho Kim,et al.  [Seven cases of decreased serum valproic acid concentration during concomitant use of carbapenem antibiotics]. , 2007, The Korean journal of laboratory medicine.

[8]  Jesse L. Lunde,et al.  Acute Seizures in a Patient Receiving Divalproex Sodium After Starting Ertapenem Therapy , 2007, Pharmacotherapy.

[9]  A. Wilmer,et al.  Meropenem -valproic acid interaction in patients with cefepime-associated status epilepticus. , 2007, American journal of health-system pharmacy : AJHP : official journal of the American Society of Health-System Pharmacists.

[10]  M. A. Mariscal,et al.  Pharmacokinetic interaction between valproic acid and ertapenem , 2006 .

[11]  R. Yumoto,et al.  Interaction of valproic acid and carbapenem antibiotics with multidrug resistance-associated proteins in rat erythrocyte membranes , 2006, Epilepsy Research.

[12]  A. Carcas,et al.  Epileptic seizures caused by low valproic acid levels from an interaction with meropenem , 2006, Journal of clinical pharmacy and therapeutics.

[13]  E. Perucca British Journal of Clinical Pharmacology Clinically Relevant Drug Interactions with Antiepileptic Drugs , 2022 .

[14]  T. Murakami,et al.  Increased erythrocyte distribution of valproic acid in pharmacokinetic interaction with carbapenem antibiotics in rat and human. , 2005, Journal of pharmaceutical sciences.

[15]  P. Hantson,et al.  Pharmacokinetic interaction between valproic acid and meropenem , 2005, Intensive Care Medicine.

[16]  R. Riva,et al.  Seizure Worsening Caused by Decreased Serum Valproate During Meropenem Therapy , 2005, Journal of child neurology.

[17]  C. N. Peters,et al.  Intravenous valproate as an innovative therapy in seizure emergency situations including status epilepticus—experience in 102 adult patients , 2005, Seizure.

[18]  J. Borrás-Blasco,et al.  Acute Seizures Due to a Probable Interaction between Valproic Acid and Meropenem , 2005, The Annals of pharmacotherapy.

[19]  Masahiro Nakamura,et al.  MECHANISM OF THE DRUG INTERACTION BETWEEN VALPROIC ACID AND CARBAPENEM ANTIBIOTICS IN MONKEYS AND RATS , 2004, Drug Metabolism and Disposition.

[20]  H. Sağlam,et al.  Meropenem decreases serum level of valproic acid. , 2004, Pediatric neurology.

[21]  K. Miyamoto,et al.  Effect of Meropenem on Disposition Kinetics of Valproate and Its Metabolites in Rabbits , 2001, Pharmaceutical Research.

[22]  M. Frye,et al.  Metabolism and Excretion of Mood Stabilizers and New Anticonvulsants , 1999, Cellular and Molecular Neurobiology.

[23]  A. Patchefsky,et al.  Case report 3 , 1976, Skeletal Radiology.

[24]  F. L. Tello,et al.  Interacción farmacocinética entre ácido valproico y antibióticos carbapenémicos: descripción de tres casos , 2003 .

[25]  Y. Takiguchi,et al.  Carbapenem antibiotics inhibit valproic acid transport in Caco-2 cell monolayers. , 2002, International journal of pharmaceutics.

[26]  Y. Takiguchi,et al.  Inhibition by carbapenem antibiotic imipenem of intestinal absorption of valproic acid in rats , 2001, The Journal of pharmacy and pharmacology.

[27]  H. Naganuma,et al.  Panipenum, a carbapenem antibiotic, increases the level of hepatic UDP-glucuronic acid in rats. , 2000, Drug metabolism and disposition: the biological fate of chemicals.

[28]  F. Camu,et al.  Lowering of plasma valproic acid concentrations during concomitant therapy with meropenem and amikacin. , 1998, The Journal of antimicrobial chemotherapy.

[29]  A. Fujimura,et al.  Panipenem-betamipron and decreases in serum valproic acid concentration. , 1998, Therapeutic drug monitoring.

[30]  T. Matsuishi,et al.  Decrease in serum levels of valproic acid during treatment with a new carbapenem, panipenem/betamipron. , 1997, The Journal of antimicrobial chemotherapy.