Real-time vector velocity assessment through multigate doppler and plane waves

Several ultrasound (US) methods have been recently proposed to produce 2-D velocity vector fields with high temporal and spatial resolution. However, the real-time implementation in US scanners is heavily hampered by the high calculation power required. In this work, we report a real-time vector Doppler imaging method which has been integrated in an open research system. The proposed approach exploits the plane waves transmitted from two sub-arrays of a linear probe to estimate the velocity vectors in 512 sample volumes aligned along the probe axis. The method has been tested for accuracy and reproducibility through simulations and in vitro experiments. Simulations over a 0° to 90° angle range of a 0.5 m/s peak parabolic flow have yielded 0.75° bias and 1.1° standard deviation for direction measurement, and 0.6 cm/s bias with 3.1% coefficient of variation for velocity assessment. In vitro tests have supported the simulation results. Preliminary measurements on the carotid artery of a volunteer have highlighted the real-time system capability of imaging complex flow configurations in an intuitive, easy, and quick way, as shown in a sample supplementary movie. These features have allowed reproducible peak velocity measurements to be obtained, as needed for quantitative investigations on patients.

[1]  K. Johnston,et al.  Interobserver variability of carotid Doppler peak velocity measurements among technologists in an ICAVL-accredited vascular laboratory. , 2004, Journal of vascular surgery.

[2]  S. Ricci,et al.  Adaptive spectral estimators for fast flow-profile detection , 2013, IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control.

[3]  G. Trahey,et al.  Angle Independent Ultrasonic Detection of Blood Flow , 1987, IEEE Transactions on Biomedical Engineering.

[4]  J. Jensen,et al.  Directional velocity estimation using focusing along the flow direction. I: theory and simulation , 2003, IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control.

[5]  K. Beach,et al.  Cross-beam vector Doppler ultrasound for angle-independent velocity measurements. , 2000, Ultrasound in medicine & biology.

[6]  J. Jensen,et al.  A new method for estimation of velocity vectors , 1998, IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control.

[7]  P. Tortoli,et al.  An automatic angle tracking procedure for feasible vector Doppler blood velocity measurements. , 2010, Ultrasound in medicine & biology.

[8]  Piero Tortoli,et al.  Accuracy and reproducibility of a novel dynamic volume flow measurement method. , 2013, Ultrasound in medicine & biology.

[9]  J Bercoff,et al.  Ultrafast compound doppler imaging: providing full blood flow characterization , 2011, IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control.

[10]  K. Kristoffersen,et al.  Parallel beamforming using synthetic transmit beams , 2007, IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control.

[11]  J. M. Hansen,et al.  Comparison of real-time in vivo spectral and vector velocity estimation. , 2012, Ultrasound in medicine & biology.

[12]  P. Tortoli,et al.  Real-time vector velocity profile measurement based on plane wave transmission , 2012, 2012 IEEE International Ultrasonics Symposium.

[13]  A. Dallai,et al.  A reconfigurable and programmable FPGA-based system for nonstandard ultrasound methods , 2012, IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control.

[14]  P. Hoskins,et al.  Velocity fluctuation reduction in vector Doppler ultrasound using a hybrid single/dual-beam algorithm , 2003, IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control.

[15]  R. Daigle,et al.  Estimation and display for Vector Doppler Imaging using planewave transmissions , 2011, 2011 IEEE International Ultrasonics Symposium.

[16]  Jørgen Arendt Jensen,et al.  Estimation of Velocity Vectors in Synthetic Aperture Ultrasound Imaging , 2006, IEEE Transactions on Medical Imaging.

[17]  J. Kortbek,et al.  Estimation of velocity vector angles using the directional cross-correlation method , 2006, IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control.

[18]  H. Torp,et al.  Simultaneous quantification of flow and tissue velocities based on multi-angle plane wave imaging , 2013, IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control.

[19]  J. Jensen,et al.  Recent advances in blood flow vector velocity imaging , 2011, 2011 IEEE International Ultrasonics Symposium.

[20]  L.N. Bohs,et al.  A novel method for angle independent ultrasonic imaging of blood flow and tissue motion , 1991, IEEE Transactions on Biomedical Engineering.

[21]  A. Dallai,et al.  ULA-OP: an advanced open platform for ultrasound research , 2009, IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control.

[22]  M. Fox Multiple crossed-beam ultrasound Doppler velocimetry , 1978 .

[23]  P. Tortoli,et al.  Noninvasive simultaneous assessment of wall shear rate and wall distension in carotid arteries. , 2006, Ultrasound in medicine & biology.

[24]  R. Shields Medical management of carotid stenosis. , 2010, Perspectives in vascular surgery and endovascular therapy.

[25]  M G Hunink,et al.  Detection and quantification of carotid artery stenosis: efficacy of various Doppler velocity parameters. , 1993, AJR. American journal of roentgenology.

[26]  P. Tortoli,et al.  Accurate Doppler angle estimation for vector flow measurements , 2006, IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control.

[27]  L. Masotti,et al.  A real-time two-dimensional pulsed-wave Doppler system. , 2000, Ultrasound in medicine & biology.

[28]  P. Tortoli,et al.  Multichannel FPGA-based arbitrary waveform generator for medical ultrasound , 2007 .

[29]  K V Ramnarine,et al.  Validation of a new blood-mimicking fluid for use in Doppler flow test objects. , 1998, Ultrasound in medicine & biology.

[30]  Pai-Chi Li,et al.  Estimating the blood velocity vector using aperture domain data , 2007, IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control.

[31]  Piero Tortoli,et al.  State of the art: non-invasive ultrasound assessment of the uteroplacental circulation. , 2007, Seminars in perinatology.

[32]  J. Jensen,et al.  Calculation of pressure fields from arbitrarily shaped, apodized, and excited ultrasound transducers , 1992, IEEE Transactions on Ultrasonics, Ferroelectrics and Frequency Control.

[33]  S. Diciotti,et al.  Accuracy and reproducibility of a novel dual-beam vector Doppler method. , 2009, Ultrasound in medicine & biology.