Sensors for Fetal and Neonatal Monitoring

The clinical care of the fetus and the newborn baby has advanced significantly over the last two decades and sensor science and technology have played their parts in this. In fact, there has been a concentration of effort from multidisciplinary groups to develop new technologies suited to the task of improving the care of the fetus and the newborn baby that can be traced back to the mid 1960s [1–6]. As a result of this effort sensors have emerged for both diagnostic and therapeutic monitoring purposes and great ingenuity has been used to solve difficult problems at the interface between sensor and signal. Nevertheless, despite the successes, many problems still remain to be solved.

[1]  Neonatal critical care monitoring. , 1986, Journal of medical engineering & technology.

[2]  J. Sleep,et al.  A randomized controlled trial to compare three types of fetal scalp electrode , 1992, British journal of obstetrics and gynaecology.

[3]  P. Rolfe Fetal and neonatal physiological measurements , 1980 .

[4]  M. Polanyi,et al.  In vivo studies with an intravascular and intracardiac reflection oximeter. , 1962, Journal of applied physiology.

[5]  P Várady,et al.  [Fetal phonocardiography with a novel approach]. , 2001, Orvosi hetilap.

[6]  T. Weber,et al.  Continuous acid‐base assessment of the human fetus during labour by tissue pH and transcutaneous carbon dioxide monitoring , 1985, British journal of obstetrics and gynaecology.

[7]  Neonatal Physiological Measurements , 1988 .

[8]  C Marque,et al.  Human abdominal EHG processing for uterine contraction monitoring. , 1989, Biotechnology.

[9]  E. Hon,et al.  THE FETAL ELECTROCARDIOGRAM. V. COMPARISON OF LEAD SYSTEMS. , 1965, American journal of obstetrics and gynecology.

[10]  S A Spencer,et al.  Cyclical fluctuations in cerebral blood volume. , 1992, Archives of disease in childhood.

[11]  S. Ginter Numerical simulation of ultrasound-thermotherapy combining nonlinear wave propagation with broadband soft-tissue absorption. , 2000, Ultrasonics.

[12]  M. Khoo,et al.  Spectral analysis of heart rate variability and respiration during sleep in cocaine-exposed neonates. , 2001, Clinical physiology.

[13]  J. Ponte,et al.  CONTINUOUS INTRAPARTUM MEASUREMENT OF FETAL OXYGEN SATURATION , 1988, The Lancet.

[14]  J. E. Lewin,et al.  AN APNŒA-ALARM MATTRESS , 1969 .

[15]  R. Robinson,et al.  Non‐invasive Method for Measuring Intracranial Pressure in Normal Newborn Infants , 1977, Developmental medicine and child neurology.

[16]  Huseyin Seker,et al.  Compensatory fuzzy neural networks-based intelligent detection of abnormal neonatal cerebral Doppler ultrasound waveforms , 2001, IEEE Transactions on Information Technology in Biomedicine.

[17]  V. Twersky Absorption and multiple scattering by biological suspensions. , 1970, Journal of the Optical Society of America.

[18]  J. Wladimiroff,et al.  Accuracy and safety of transvaginal sonographic placental localization. , 1990, Obstetrics and gynecology.

[19]  Dawes Gs Breathing before birth in animals and man. An essay in developmental medicine. , 1974 .

[20]  D. Read,et al.  CONTINUOUS INTRA-ARTERIAL PO2 IN NORMAL MAN USING A FLEXIBLE MICROELECTRODE. , 1963, Journal of applied physiology.

[21]  S R Arridge,et al.  The theoretical basis for the determination of optical pathlengths in tissue: temporal and frequency analysis. , 1992, Physics in medicine and biology.

[22]  J. Gardosi,et al.  CONTINUOUS INTRAPARTUM MONITORING OF FETAL OXYGEN SATURATION , 1989, The Lancet.

[23]  J. Veille,et al.  Middle cerebral artery blood flow in normal and growth-retarded fetuses. , 1990, American journal of obstetrics and gynecology.

[24]  H. Schneider [Birth asphyxia - an unsolved problem of perinatal medicine]. , 2001, Zeitschrift fur Geburtshilfe und Neonatologie.

[25]  G. Schuler,et al.  Fetal ECG improvement due to selective signal addition. , 1968, American journal of obstetrics and gynecology.

[26]  C Marque,et al.  Electrohysterography during pregnancy: preliminary report. , 1993, Biomedical instrumentation & technology.

[27]  Continuous intrapartum measurement of tissue pH of the human fetus using newly developed techniques , 1991, Journal of perinatal medicine.

[28]  L. C. Henyey,et al.  Diffuse radiation in the Galaxy , 1940 .

[29]  J. Horbar,et al.  Effect of application force on noninvasive measurements of intracranial pressure. , 1980, Pediatrics.

[30]  F S Barnes,et al.  Improved phonocardiogram system based on acoustic impedance matching. , 1980, The American journal of physiology.

[31]  U. Haller,et al.  19. Continuous tissue pH measurement on the fetus during delivery , 1978, Archives of gynecology.

[32]  U. Gembruch,et al.  Color Doppler flow mapping of fetal heart , 1991, Journal of perinatal medicine.

[33]  N. Lassen,et al.  Impaired autoregulation of cerebral blood flow in the distressed newborn infant. , 1979, The Journal of pediatrics.

[34]  Y. Shimada,et al.  Spectrophotometric monitoring of arterial oxygen saturation in the fingertip , 2006, Medical and Biological Engineering and Computing.

[35]  M. Kühnert,et al.  Predictive agreement between the fetal arterial oxygen saturation and fetal scalp pH: results of the German multicenter study. , 1998, American journal of obstetrics and gynecology.

[36]  P Rolfe,et al.  Fetal and neonatal cerebral oxygen monitoring with NIRS: theory and practice. , 1992, Early human development.

[37]  Susan Wray,et al.  QUANTIFICATION OF CEREBRAL OXYGENATION AND HAEMODYNAMICS IN SICK NEWBORN INFANTS BY NEAR INFRARED SPECTROPHOTOMETRY , 1986, The Lancet.

[38]  G. C. Pomraning,et al.  Linear Transport Theory , 1967 .

[39]  A. Hill,et al.  Intracranial pressure measurements in the newborn. , 1985, Clinics in perinatology.

[40]  L. Leader,et al.  Continuous Intrapartum Fetal Monitoring: A Prospective Randomized Comparison of 2 Types of Fetal Scalp Electrode , 1993, The Australian & New Zealand journal of obstetrics & gynaecology.

[41]  J. Brazy,et al.  Noninvasive monitoring of cerebral oxygenation in preterm infants: preliminary observations. by brazy je, lewis dv, mitnick mh, and joubsis vander vliet ff. pediatrics 1985; 75:217–225 , 1985, Pediatrics.

[42]  Stow Rw,et al.  Rapid measurement of the tension of carbon dioxide in blood. , 1957 .

[43]  S. Arridge,et al.  Estimation of optical pathlength through tissue from direct time of flight measurement , 1988 .

[44]  P Rolfe,et al.  [Blood volume changes and oxygenation during labor--a laser spectroscopic analysis]. , 2001, Zeitschrift fur Geburtshilfe und Neonatologie.

[45]  H W Jongsma,et al.  Accuracy of fetal pulse oximetry and pitfalls in measurements. , 1997, European journal of obstetrics, gynecology, and reproductive biology.

[46]  S. Mannor,et al.  The safety of ultrasound in fetal monitoring. , 1972, American journal of obstetrics and gynecology.

[47]  A. Philip,et al.  Noninvasive monitoring of intracranial pressure: a new approach for neonatal clinical pharmacology. , 1979, Clinics in perinatology.

[48]  Kazuhiko Ishihara,et al.  Preparation of Phospholipid Polylners and Their Properties as Polymer Hydrogel Membranes , 1990, Polymer Journal.

[49]  E. Hon,et al.  Instrumentation of fetal heart rate and fetal electrocardiography. II. A vaginal electrode. , 1963, American journal of obstetrics and gynecology.

[50]  H. Bucher,et al.  Hyperoxemia in newborn infants: detection by pulse oximetry. , 1989, Pediatrics.

[51]  C N SMYTH,et al.  THE GUARD‐RING TOCODYNAMOMETER , 1957, The Journal of obstetrics and gynaecology of the British Empire.

[52]  H. Hochberg,et al.  Automatic detection of fetal movement by Doppler ultrasound during non‐stress testing , 1982, International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics.

[53]  Fox Rh,et al.  A new technique for monitoring the deep body temperature in man from the intact skin surface. , 1971, The Journal of physiology.

[54]  R. Lilford,et al.  CONTINUOUS INTRAPARTUM MEASUREMENT OF FETAL OXYGEN SATURATION , 1988, The Lancet.

[55]  P Rolfe,et al.  Non-invasive optical methods for the study of cerebral metabolism in the human newborn: a technique for the future? , 1985, Journal of medical engineering & technology.

[56]  A. Schuster Radiation through a foggy atmosphere , 1903 .

[57]  M. Moulden,et al.  A computer system for the numerical analysis of nonstress tests. , 2002, American journal of obstetrics and gynecology.

[58]  F. Kreuzer,et al.  Method of Polarographic in vivo Continuous Recording of Blood Oxygen Tension , 1958, Science.

[59]  P. Naylor,et al.  The oxygen tension gradient across human epidermis. , 1967, Respiration physiology.

[60]  A. Wilkinson,et al.  Continuous measurement of oxygen saturation in sick newborn infants. , 1978, The Journal of pediatrics.

[61]  S. Koeff,et al.  Continuous measurements of intravascular oxygen tension in normal adults. , 1962, The Journal of clinical investigation.

[62]  I. Korhonen,et al.  Multivariate autoregressive modelling combined with transcephalic electrical impedance: method to relate neonatal systemic circulation and respiration to cerebral circulation , 1995, Medical and Biological Engineering and Computing.

[63]  Britton Chance,et al.  Phase modulation system for dual wavelength difference spectroscopy of hemoglobin deoxygenation in tissues , 1990, Photonics West - Lasers and Applications in Science and Engineering.

[64]  B. Wilson,et al.  The propagation of optical radiation in tissue I. Models of radiation transport and their application , 1991, Lasers in Medical Science.

[65]  K. Maršál,et al.  Cardiotocography only versus cardiotocography plus ST analysis of fetal electrocardiogram for intrapartum fetal monitoring: a Swedish randomised controlled trial , 2001, The Lancet.

[66]  Akira Ishimaru,et al.  Wave propagation and scattering in random media , 1997 .

[67]  H. Marcovitch,et al.  A disposable catheter-tip transducer for continuous measurement of blood oxygen tension in vivo. , 1971, Biomedical engineering.

[68]  P. Rolfe,et al.  Ion-selective sensors for assessment of the fetus. , 1988, Journal of Biomedical Engineering.

[69]  N. Lundberg,et al.  Continuous recording and control of ventricular fluid pressure in neurosurgical practice. , 1962, Acta psychiatrica Scandinavica. Supplementum.

[70]  O. Rompelman,et al.  Recording fetal breathing movements with a passive transducer based on an inductive principle , 2006, Medical and Biological Engineering and Computing.

[71]  Frederick W. Kremkau,et al.  Diagnostic ultrasound: Principles, instrumentation, and exercises , 1984 .

[72]  D. Miller,et al.  Body temperature in the immediate neonatal period: the effect of reducing thermal losses. , 1966, American journal of obstetrics and gynecology.

[73]  F. Boehm,et al.  The clinical significance of intermittent sinusoidal fetal heart rate. , 1999, American journal of obstetrics and gynecology.

[74]  Catherine Marque,et al.  Rejection of the maternal electrocardiogram in the electrohysterogram signal , 2000, IEEE Transactions on Biomedical Engineering.

[75]  K. Greene,et al.  Changes in the ST waveform of the fetal lamb electrocardiogram with hypoxemia. , 1982, American journal of obstetrics and gynecology.

[76]  G S Dawes,et al.  Pattern of the normal human fetal heart rate , 1982, British journal of obstetrics and gynaecology.

[77]  J. Duderstadt,et al.  Nuclear reactor analysis , 1976 .

[78]  D. Chapman,et al.  Biomembrane surfaces as models for polymer design: the potential for haemocompatibility. , 1984, Biomaterials.

[79]  S. Kety,et al.  THE NITROUS OXIDE METHOD FOR THE QUANTITATIVE DETERMINATION OF CEREBRAL BLOOD FLOW IN MAN: THEORY, PROCEDURE AND NORMAL VALUES. , 1948, The Journal of clinical investigation.

[80]  Britton Chance,et al.  Measurement of biological tissue metabolism using phase modulation spectroscopic technology , 1991, Photonics West - Lasers and Applications in Science and Engineering.

[81]  E. Bishop Obstetric uses of the ultrasonic motion sensor. , 1966, American journal of obstetrics and gynecology.

[82]  J. Volpe,et al.  Normal pressure hydrocephalus in the newborn. , 1981, Pediatrics.

[83]  T. Weber,et al.  [Cardiotocographic monitoring of deliveries. A prospective comparative study of 2 types of electrodes]. , 1989, Ugeskrift for læger.

[84]  D. G. Talbert,et al.  Wide Bandwidlt Fetal Phonography Using a Sensor Matched to the Compliance of the Mother's Abdominal Wall , 1986, IEEE Transactions on Biomedical Engineering.

[85]  J. Brazy,et al.  Cerebral oxygen monitoring with near infrared spectroscopy: Clinical application to neonates , 1991, Journal of Clinical Monitoring.

[86]  D. Delpy,et al.  COTSIDE MEASUREMENT OF CEREBRAL BLOOD FLOW IN ILL NEWBORN INFANTS BY NEAR INFRARED SPECTROSCOPY , 1988, The Lancet.

[87]  P Rolfe A magnetometer respiration monitor for use with premature babies. , 1971, Biomedical engineering.

[88]  Steven J. Matcher,et al.  Absolute quantification methods in tissue near-infrared spectroscopy , 1995, Photonics West.

[89]  P Rolfe Monitoring in newborn intensive care. , 1975, Biomedical engineering.

[90]  H.P. van Geijn,et al.  A transducer for detection of fetal breathing movements , 1989, IEEE Transactions on Biomedical Engineering.

[91]  E. Hon,et al.  Instrumentation of fetal electrocardiography. , 1957, Science.

[92]  Towards non-invasive monitoring of cerebral metabolism , 1986 .

[93]  B. Wilson,et al.  Time resolved reflectance and transmittance for the non-invasive measurement of tissue optical properties. , 1989, Applied optics.

[94]  Martin Wolf,et al.  Cyclical fluctuations in blood pressure, heart rate and cerebral blood volume in preterm infants , 1999, Brain and Development.

[95]  E. Hon,et al.  The fetal electrocardiogram , 1965 .

[96]  S Nioka,et al.  Comparison of time-resolved and -unresolved measurements of deoxyhemoglobin in brain. , 1988, Proceedings of the National Academy of Sciences of the United States of America.

[97]  J S Curnow,et al.  Suitability of fetal scalp electrodes for monitoring the fetal electrocardiogram during labour. , 1990, Clinical physics and physiological measurement : an official journal of the Hospital Physicists' Association, Deutsche Gesellschaft fur Medizinische Physik and the European Federation of Organisations for Medical Physics.

[98]  A. Wilkinson,et al.  New fontanometer for continuous estimation of intracranial pressure in the newborn. , 1987, Archives of disease in childhood.

[99]  F. Jöbsis Noninvasive, infrared monitoring of cerebral and myocardial oxygen sufficiency and circulatory parameters. , 1977, Science.

[100]  Hon Eh,et al.  THE FETAL ELECTROCARDIOGRAM. I. THE ELECTROCARDIOGRAM OF THE DYING FETUS. , 1963 .

[101]  E Gratton,et al.  Frequency-domain method for measuring spectral properties in multiple-scattering media: methemoglobin absorption spectrum in a tissuelike phantom. , 1995, Applied optics.

[102]  P Rolfe,et al.  Development of a haemocompatible pO2 sensor with phospholipid-based copolymer membrane. , 1996, Biosensors & bioelectronics.