Using CARREL + to Increase Availability of Human Organs for Transplantation

The shortage of human organs for transplantation is a serious problem, and is exacerbated by the fact that current organ selection and assignment processes discard a significant number of organs deemed non-viable (not suitable) for transplantation. However, these processes ignore the fact that medical specialists may disagree as to whether an organ is viable or not. Therefore, in this paper we propose a novel organ selection process in which transplant physicians, who may be geographically dispersed, deliberate over the viability of an organ. This argument-based deliberation is formalized in amulti-agent system - CARREL+ - that requires the deliberation to adhere to formal rigorous standards acknowledging the safety critical nature of the domain. We believe that this new selection process has the potential to increase the number of organs that current selection processes make available for transplantation, and thus reduce the increasing gap between the demand for and supply of human organs.

[1]  Ulises Cortés,et al.  Increasing Human-Organ Transplant Availability: Argumentation-Based Agent Deliberation , 2006, IEEE Intelligent Systems.

[2]  Francisco Caballero,et al.  Extended criteria for organ acceptance. Strategies for achieving organ safety and for increasing organ pool , 2003, Clinical transplantation.

[3]  Alexander Gelbukh,et al.  MICAI 2005: Advances in Artificial Intelligence, 4th Mexican International Conference on Artificial Intelligence, Monterrey, Mexico, November 14-18, 2005, Proceedings , 2005, MICAI.

[4]  D. Walton Argumentation Schemes for Presumptive Reasoning , 1995 .

[5]  Phan Minh Dung,et al.  On the Acceptability of Arguments and its Fundamental Role in Nonmonotonic Reasoning, Logic Programming and n-Person Games , 1995, Artif. Intell..

[6]  Richard P. Cooper,et al.  Modelling high-level cognitive processes , 2002 .

[7]  Ulises Cortés,et al.  The organ allocation process: a natural extension of the Carrel Agent-Mediated Electronic Institution , 2003, AI Commun..

[8]  Miquel Sànchez-Marrè,et al.  CBR and Argument Schemes for Collaborative Decision Making , 2006, COMMA.

[9]  Ulises Cortés,et al.  Towards Formalising Agent Argumentation over the Viability of Human Organs for Transplantation , 2005, MICAI.

[10]  Ulises Cortés,et al.  Argument Schemes and Critical Questions for Heterogeneous Agents to Argue over the Viability of a Human Organ for Transplantation , 2006, AAAI Spring Symposium: Argumentation for Consumers of Healthcare.