Electronic Structure Engineering of Cu2O Film/ZnO Nanorods Array All-Oxide p-n Heterostructure for Enhanced Photoelectrochemical Property and Self-powered Biosensing Application

We have engineered the electronic structure at the interface between Cu2O and ZnO nanorods (NRs) array, through adjusting the carrier concentration of Cu2O. The electrodeposition of Cu2O at pH 11 acquired the highest carrier concentration, resulting in the largest interfacial electric field between Cu2O and ZnO, which finally led to the highest separation efficiency of photogenerated charge carriers. The optimized Cu2O/ZnO NRs array p-n heterostructures exhibited enhanced PEC performance, such as elevated photocurrent and photoconversion efficiency, as well as excellent sensing performance for the sensitive detection of glutathione (GSH) in PBS buffer even at applied bias of 0 V which made the device self-powered. Besides, the favorable selectivity, high reproducibility and extremely wide detection range, make such heterostructure a promising candidate for PEC biosensing applications, probably for the extended field of PEC water splitting or other solar photovoltaic beacons.

[1]  S. Sorbi,et al.  Gluthatione level is altered in lymphoblasts from patients with familial Alzheimer's disease , 1999, Neuroscience Letters.

[2]  Pei Lin,et al.  Enhanced photoresponse of Cu2O/ZnO heterojunction with piezo-modulated interface engineering , 2014, Nano Research.

[3]  Andreas J Meyer,et al.  Real-time imaging of the intracellular glutathione redox potential , 2008, Nature Methods.

[4]  M. Shen,et al.  High-efficiency ferroelectric-film solar cells with an n-type Cu₂O cathode buffer layer. , 2012, Nano letters.

[5]  S. Zhuiykov,et al.  Enhancing the current density of electrodeposited ZnO–Cu2O solar cells by engineering their heterointerfaces , 2012 .

[6]  U. Gibson,et al.  A Simple Two-Step Electrodeposition of Cu2O/ZnO Nanopillar Solar Cells , 2010 .

[7]  Kevin P. Musselman,et al.  A Novel Buffering Technique for Aqueous Processing of Zinc Oxide Nanostructures and Interfaces, and Corresponding Improvement of Electrodeposited ZnO‐Cu2O Photovoltaics , 2011 .

[8]  Pei Lin,et al.  Functional nanogenerators as vibration sensors enhanced by piezotronic effects , 2014, Nano Research.

[9]  Wei-Wei Zhao,et al.  Bismuthoxyiodide Nanoflakes/Titania Nanotubes Arrayed p-n Heterojunction and Its Application for Photoelectrochemical Bioanalysis , 2014, Scientific Reports.

[10]  G. Jung,et al.  3D Branched nanowire photoelectrochemical electrodes for efficient solar water splitting. , 2013, ACS nano.

[11]  Hui Jiang,et al.  Photoelectrocatalytic oxidation of glutathione based on porous TiO2-Pt nanowhiskers. , 2012, Langmuir : the ACS journal of surfaces and colloids.

[12]  V. Meininger,et al.  Blood oxidative stress in amyotrophic lateral sclerosis , 2000, Journal of the Neurological Sciences.

[13]  Zhuo Kang,et al.  Enhanced photoelectrochemical property of ZnO nanorods array synthesized on reduced graphene oxide for self-powered biosensing application. , 2015, Biosensors & bioelectronics.

[14]  Ming Xu,et al.  Photoelectrochemical detection of glutathione by IrO2-hemin-TiO2 nanowire arrays. , 2013, Nano letters.

[15]  T. Shi,et al.  Quantum dot-sensitized hierarchical micro/nanowire architecture for photoelectrochemical water splitting. , 2014, ACS nano.

[16]  Zhiqun Lin,et al.  p-n Heterojunction photoelectrodes composed of Cu2O-loaded TiO2 nanotube arrays with enhanced photoelectrochemical and photoelectrocatalytic activities , 2013 .

[17]  E. Farjami,et al.  Simultaneous electrochemical determination of glutathione and glutathione disulfide at a nanoscale copper hydroxide composite carbon ionic liquid electrode. , 2009, Analytical chemistry.

[18]  Kun Yang,et al.  Gold nanoparticle modified silicon nanowires as biosensors , 2006 .

[19]  K. Musselman,et al.  Novel Atmospheric Growth Technique to Improve Both Light Absorption and Charge Collection in ZnO/Cu2O Thin Film Solar Cells , 2013 .

[20]  Guohua Chen,et al.  Photoeletrocatalytic activity of a Cu2O-loaded self-organized highly oriented TiO2 nanotube array electrode for 4-chlorophenol degradation. , 2009, Environmental science & technology.

[21]  Qing-Ming Wang,et al.  Electrodeposition of hierarchical ZnO/Cu2O nanorod films for highly efficient visible-light-driven photocatalytic applications , 2014 .

[22]  Wei Wang,et al.  Facile electrodeposition of environment-friendly Cu2O/ZnO heterojunction for robust photoelectrochemical biosensing , 2014 .

[23]  Qingliang Liao,et al.  Scanning Probe Study on the Piezotronic Effect in ZnO Nanomaterials and Nanodevices , 2012, Advanced materials.

[24]  Bingqiang Cao,et al.  Photovoltaic Efficiency Enhancement of Cu2O Solar Cells Achieved by Controlling Homojunction Orientation and Surface Microstructure , 2012 .

[25]  P. Gorostiza,et al.  Direct Observation of the Valence Band Edge by in Situ ECSTM-ECTS in p-Type Cu2O Layers Prepared by Copper Anodization , 2009 .

[26]  Peidong Yang,et al.  Nanowire dye-sensitized solar cells , 2005, Nature materials.

[27]  Shengchao Zhu,et al.  Photoelectrochemical sensor for the rapid detection of in situ DNA damage induced by enzyme-catalyzed fenton reaction. , 2008, Environmental science & technology.

[28]  Longhua Tang,et al.  Graphene oxide amplified electrogenerated chemiluminescence of quantum dots and its selective sensing for glutathione from thiol-containing compounds. , 2009, Analytical chemistry.

[29]  Xiaoru Zhang,et al.  A new photoelectrochemical aptasensor for the detection of thrombin based on functionalized graphene and CdSe nanoparticles multilayers. , 2011, Chemical communications.

[30]  J. Jog,et al.  Strong photo-response in a flip-chip nanowire p-Cu2O/n-ZnO junction. , 2011, Nanoscale.

[31]  Weichao Wang,et al.  pH-dependence of conduction type in cuprous oxide synthesized from solution , 2010 .

[32]  Liping Chen,et al.  Carrier concentration-dependent electron transfer in Cu₂O/ZnO nanorod arrays and their photocatalytic performance. , 2013, Nanoscale.

[33]  P. Yang,et al.  Nanowire-based all-oxide solar cells. , 2009, Journal of the American Chemical Society.

[34]  Marc Vendrell,et al.  Intracellular glutathione detection using MnO(2)-nanosheet-modified upconversion nanoparticles. , 2011, Journal of the American Chemical Society.

[35]  Jyoti Jog,et al.  Cu2O/ZnO hetero-nanobrush: hierarchical assembly, field emission and photocatalytic properties , 2012 .

[36]  Huangxian Ju,et al.  Low-potential photoelectrochemical biosensing using porphyrin-functionalized TiO₂ nanoparticles. , 2010, Analytical chemistry.

[37]  Qingming Shen,et al.  Fabrication of glutathione photoelectrochemical biosensor using graphene-CdS nanocomposites. , 2012, The Analyst.

[38]  E. Flagg,et al.  Glutathione in human plasma: decline in association with aging, age-related macular degeneration, and diabetes. , 1998, Free radical biology & medicine.

[39]  Hsin-Ying Lin,et al.  Simple fabrication and improved photoresponse of ZnO-Cu2O core-shell heterojunction nanorod arrays , 2010 .

[40]  R. S. Martin,et al.  Use of microchip electrophoresis and a palladium/mercury amalgam electrode for the separation and detection of thiols , 2011 .

[41]  K. Musselman,et al.  Incompatible Length Scales in Nanostructured Cu2O Solar Cells , 2012 .

[42]  Ying Yu,et al.  p-Type and n-type Cu2O semiconductor thin films: Controllable preparation by simple solvothermal method and photoelectrochemical properties , 2011 .

[43]  A. Jain,et al.  Correlation between blood antioxidant levels and lipid peroxidation in rheumatoid arthritis. , 1997, Clinical biochemistry.

[44]  Yan Zhang,et al.  Application of ZnO/graphene and S6 aptamers for sensitive photoelectrochemical detection of SK-BR-3 breast cancer cells based on a disposable indium tin oxide device. , 2014, Biosensors & bioelectronics.

[45]  P. Hering,et al.  The band alignment of Cu2O/ZnO and Cu2O/GaN heterostructures , 2012 .

[46]  Liping Guo,et al.  Application of electrochemical properties of ordered mesoporous carbon to the determination of glutathione and cysteine. , 2009, Analytical biochemistry.

[47]  Lan-sun Zheng,et al.  Semiconductor@metal-organic framework core-shell heterostructures: a case of ZnO@ZIF-8 nanorods with selective photoelectrochemical response. , 2013, Journal of the American Chemical Society.

[48]  R. C. King,et al.  Handbook of X Ray Photoelectron Spectroscopy: A Reference Book of Standard Spectra for Identification and Interpretation of Xps Data , 1995 .