MeWAnalysis by the Confidence Profile Method: The Statistical Synthesis of Evidence

Part 1 Examples of problems - vignettes: setting up the analysis - formulating the problem organizing the evidence types of evidence biases summarizing the evidence influence diagrams models for combining evidence introduction to Bayes' Formula. Part 2 Formulas of the confidence profile method: components of the confidence profile method the general model prior distributions likelihood functions bias functions other functions solution methods. Part 3 Solutions to the example problems: analysis of tamoxifen analysis of HIP trial of breast cancer screening analysis of Ulrecht Project (DOM) analysis of breast cancer screening - seven controlled trials Analysis of Breast Cancer Detection Demonstration Project (BCDDP) analysis of t-Pa Analysis of Anisoylated Plasminogen Streptokinase Activated Complex (APSAC) analysis of amlodipine analysis of alcohol and breast cancer analysis of screening for maple syrup urine disease analysis of nitrogen dioxide and respiratory illness in children analysis of surveillance of colorectal cancer patients analysis of colon cancer screening trial. Part 4 Implementation issues: sensitivity analysis research planning data collection and reporting test case. Conclusions: other meta-analysis methods summary and conclusions.