DNA adducts: effects of low exposure to ethylene oxide, vinyl chloride and butadiene.

[1]  J. Swenberg,et al.  1,3-butadiene: cancer, mutations, and adducts. Part V: Hemoglobin adducts as biomarkers of 1,3-butadiene exposure and metabolism. , 2000, Research report.

[2]  J. Swenberg,et al.  Molecular dosimetry of endogenous and ethylene oxide-induced N7-(2-hydroxyethyl) guanine formation in tissues of rodents. , 1999, Carcinogenesis.

[3]  J. Swenberg,et al.  A gas chromatography/electron capture/negative chemical ionization high-resolution mass spectrometry method for analysis of endogenous and exogenous N7-(2-hydroxyethyl)guanine in rodents and its potential for human biological monitoring. , 1999, Chemical research in toxicology.

[4]  N. Tretyakova,et al.  Molecular dosimetry of N-7 guanine adduct formation in mice and rats exposed to 1,3-butadiene. , 1999, Chemical research in toxicology.

[5]  X. Le,et al.  Inducible repair of thymine glycol detected by an ultrasensitive assay for DNA damage. , 1998, Science.

[6]  N. Tretyakova,et al.  Quantitative analysis of 1,3-butadiene-induced DNA adducts in vivo and in vitro using liquid chromatography electrospray ionization tandem mass spectrometry. , 1998, Journal of mass spectrometry : JMS.

[7]  T. Fennell,et al.  Ethylene oxide dosimetry in the mouse. , 1998, Toxicology and applied pharmacology.

[8]  K. Peltonen,et al.  DNA adducts in mouse testis and lung after inhalation exposure to 1,3-butadiene. , 1998, Mutation research.

[9]  F. Chung,et al.  Effect of glutathione depletion on exocyclic adduct levels in the liver DNA of F344 rats. , 1997, Chemical research in toxicology.

[10]  N. Tretyakova,et al.  Adenine adducts with diepoxybutane: isolation and analysis in exposed calf thymus DNA. , 1997, Chemical research in toxicology.

[11]  H. Bartsch,et al.  High dietary omega-6 polyunsaturated fatty acids drastically increase the formation of etheno-DNA base adducts in white blood cells of female subjects. , 1997, Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology.

[12]  J. Swenberg,et al.  Synthesis, characterization, and in vitro quantitation of N-7-guanine adducts of diepoxybutane. , 1997, Chemical research in toxicology.

[13]  J. A. Bond,et al.  Toxicology and epidemiology of 1,3-butadiene. , 1997, Critical reviews in toxicology.

[14]  N. Tretyakova,et al.  Identification and quantitation of DNA adducts from calf thymus DNA exposed to 3,4-epoxy-1-butene. , 1997, Carcinogenesis.

[15]  H. C. Chen,et al.  Lipid peroxidation as a potential endogenous source for the formation of exocyclic DNA adducts. , 1996, Carcinogenesis.

[16]  J. Swenberg,et al.  DNA adducts: biological markers of exposure and potential applications to risk assessment. , 1996, Mutation research.

[17]  T. Fennell,et al.  In vivo and in vitro kinetics of ethylene oxide metabolism in rats and mice. , 1996, Toxicology and applied pharmacology.

[18]  K. Peltonen,et al.  Preparation, characterization and 32P-postlabeling of butadiene monoepoxide N6-adenine adducts. , 1995, Carcinogenesis.

[19]  J A Swenberg,et al.  Dose-response relationships for carcinogens. , 1995, Toxicology letters.

[20]  H. Bartsch,et al.  1,N6-ethenodeoxyadenosine and 3,N4-ethenodeoxycytine in liver DNA from humans and untreated rodents detected by immunoaffinity/32P-postlabeling. , 1995, Carcinogenesis.

[21]  J. Swenberg,et al.  A comparison of two ultrasensitive methods for measuring 1,N6-etheno-2'-deoxyadenosine and 3,N4-etheno-2'-deoxycytidine in cellular DNA. , 1994, Carcinogenesis.

[22]  T. Skopek,et al.  Mutagenicity of butadiene and its epoxide metabolites: I. Mutagenic potential of 1,2-epoxybutene, 1,2,3,4-diepoxybutane and 3,4-epoxy-1,2-butanediol in cultured human lymphoblasts. , 1994, Carcinogenesis.

[23]  H. Bartsch,et al.  Formation, detection, and role in carcinogenesis of ethenobases in DNA. , 1994, Drug metabolism reviews.

[24]  L. Marnett,et al.  Endogenous DNA adducts: potential and paradox. , 1993, Chemical research in toxicology.

[25]  K. Peltonen,et al.  Biomonitoring of exposure to 1,3-butadiene: detection by high-performance liquid chromatography and 32P-postlabelling of an adenine adduct formed by diepoxybutane. , 1993, IARC scientific publications.

[26]  T. Skopek,et al.  Molecular dosimetry of ethylene oxide: formation and persistence of 7-(2-hydroxyethyl)guanine in DNA following repeated exposures of rats and mice. , 1992, Cancer research.

[27]  H. Bartsch,et al.  Etheno adducts formed in DNA of vinyl chloride-exposed rats are highly persistent in liver. , 1992, Carcinogenesis.

[28]  L. Loeb,et al.  The vinyl chloride DNA derivative N2,3-ethenoguanine produces G----A transitions in Escherichia coli. , 1991, Proceedings of the National Academy of Sciences of the United States of America.

[29]  J. Essigmann,et al.  Site-specific mutagenesis: retrospective and prospective. , 1991, Carcinogenesis.

[30]  F. Chung,et al.  Stereoselective formation of in vitro nucleic acid adducts by 2,3-epoxy-4-hydroxynonanal. , 1991, Cancer research.

[31]  J. Swenberg,et al.  Macromolecular adducts of ethylene oxide: a literature review and a time-course study on the formation of 7-(2-hydroxyethyl)guanine following exposures of rats by inhalation. , 1990, Mutation research.

[32]  J. Swenberg,et al.  Vinyl chloride-induced DNA adducts. II: Formation and persistence of 7-(2'-oxoethyl)guanine and N2,3-ethenoguanine in rat tissue DNA. , 1990, Carcinogenesis.

[33]  J. Swenberg,et al.  Vinyl chloride-induced DNA adducts. I: Quantitative determination of N2,3-ethenoguanine based on electrophore labeling. , 1990, Carcinogenesis.

[34]  H. Bartsch,et al.  Investigations on the relationship between DNA ethenobase adduct levels in several organs of vinyl chloride-exposed rats and cancer susceptibility. , 1990, Biochemical pharmacology.

[35]  R. Albertini,et al.  Concentration‐response curves for ethylene‐oxide‐induced heritable translocations and dominant lethal mutations , 1990, Environmental and molecular mutagenesis.

[36]  L. Rhomberg,et al.  Quantitative estimation of the genetic risk associated with the induction of heritable translocations at low‐dose exposure: Ethylene oxide as an example , 1990, Environmental and molecular mutagenesis.

[37]  H. Bartsch,et al.  Lack of miscoding properties of 7-(2-oxoethyl)guanine, the major vinyl chloride-DNA adduct. , 1985, Cancer research.

[38]  G. Bellucci,et al.  The reaction of 3,4-epoxy-1-butene with deoxyguanosine and DNA in vitro: synthesis and characterization of the main adducts. , 1984, Carcinogenesis.

[39]  E. Miller.  Some current perspectives on chemical carcinogenesis in humans and experimental animals: Presidential Address. , 1978, Cancer research.