Synthesis of the first sulfur-35-labeled hERG radioligand.

[1]  W. Chai,et al.  Non-imidazole heterocyclic histamine H3 receptor antagonists. , 2003, Bioorganic & medicinal chemistry letters.

[2]  F. Ponti,et al.  QT-interval prolongation by non-cardiac drugs: lessons to be learned from recent experience , 2000, European Journal of Clinical Pharmacology.

[3]  L. V. D. van der Ploeg,et al.  Development of a high specific activity sulfur-35-labeled sulfonamide radioligand that allowed the identification of a new growth hormone secretagogue receptor. , 1996, Journal of medicinal chemistry.

[4]  G. Robertson,et al.  HERG, a human inward rectifier in the voltage-gated potassium channel family. , 1995, Science.

[5]  D. Cai,et al.  Asymmetric Synthesis of MK-0499 , 1995 .

[6]  M. Sanguinetti,et al.  A mechanistic link between an inherited and an acquird cardiac arrthytmia: HERG encodes the IKr potassium channel , 1995, Cell.

[7]  M. Sanguinetti,et al.  Cardiac electrophysiologic and antiarrhythmic actions of two long-acting spirobenzopyran piperidine class III agents, L-702,958 and L-706,000 [MK-499]. , 1994, The Journal of pharmacology and experimental therapeutics.

[8]  J. Warmke,et al.  A family of potassium channel genes related to eag in Drosophila and mammals. , 1994, Proceedings of the National Academy of Sciences of the United States of America.

[9]  M. Sanguinetti,et al.  Two components of cardiac delayed rectifier K+ current. Differential sensitivity to block by class III antiarrhythmic agents , 1990, The Journal of general physiology.

[10]  Hao Wang,et al.  Functional and pharmacological properties of canine ERG potassium channels. , 2003, American journal of physiology. Heart and circulatory physiology.

[11]  O. Pongs,et al.  Screening lead compounds for QT interval prolongation. , 2001, Drug discovery today.

[12]  C. January,et al.  Properties of HERG channels stably expressed in HEK 293 cells studied at physiological temperature. , 1998, Biophysical journal.

[13]  S. Weinreb,et al.  β-Trimethylsilylethanesulfonyl chloride (SES-Cl): A new reagent for protection of amines , 1986 .