Biallelic expression of all four IGF-II promoters and its association with increased methylation of H19 gene in human brain

[1]  A. Hoffman,et al.  Alterations in the Promoter-specific Imprinting of the Insulin-like Growth Factor-II Gene in Wilms Tumor (*) , 1996, The Journal of Biological Chemistry.

[2]  G. Riou,et al.  High incidence of loss of heterozygosity and abnormal imprinting of H19 and IGF2 genes in invasive cervical carcinomas. Uncoupling of H19 and IGF2 expression and biallelic hypomethylation of H19. , 1996, Oncogene.

[3]  S. Zhan,et al.  Loss of imprinting of IGF2 in Ewing's sarcoma. , 1995, Oncogene.

[4]  W. Isaacs,et al.  Regional loss of imprinting of the insulin-like growth factor II gene occurs in human prostate tissues. , 1995, Clinical cancer research : an official journal of the American Association for Cancer Research.

[5]  S. Hirschfeld,et al.  Concordant Loss of Imprinting of the Human Insulin-like Growth Factor II Gene Promoters in Cancer (*) , 1995, Journal of Biological Chemistry.

[6]  A. Reeve,et al.  Altered specificity of IGF2 promoter imprinting during fetal development and onset of Wilms tumour. , 1995, Oncogene.

[7]  T. Ekström,et al.  Expression, promoter usage and parental imprinting status of insulin-like growth factor II (IGF2) in human hepatoblastoma: uncoupling of IGF2 and H19 imprinting. , 1995, Oncogene.

[8]  D. Hanahan,et al.  Deregulation of both imprinted and expressed alleles of the insulin–like growth factor 2 gene during β–cell tumorigenesis , 1995, Nature Genetics.

[9]  S. Tilghman,et al.  Disruption of imprinting caused by deletion of the H19 gene region in mice , 1995, Nature.

[10]  A. Hoffman,et al.  Differential biallelic activation of three insulin-like growth factor II promoters in the mouse central nervous system. , 1995, Molecular endocrinology.

[11]  A. Hoffman,et al.  Insulin-like growth factor II in uterine smooth-muscle tumors: maintenance of genomic imprinting in leiomyomata and loss of imprinting in leiomyosarcomata. , 1995, The Journal of clinical endocrinology and metabolism.

[12]  A. Feinberg,et al.  Loss of imprinting in hepatoblastoma. , 1995, Cancer research.

[13]  A. Reeve,et al.  Epigenetic changes encompassing the IGF2/H19 locus associated with relaxation of IGF2 imprinting and silencing of H19 in Wilms tumor. , 1995, Proceedings of the National Academy of Sciences of the United States of America.

[14]  T. Ekström,et al.  Promoter-specific IGF2 imprinting status and its plasticity during human liver development. , 1995, Development.

[15]  A. Hoffman,et al.  Promoter-specific imprinting of the human insulin-like growth factor-II gene , 1994, Nature.

[16]  M. Cosma,et al.  Parental imprinting of rat insulin-like growth factor II gene promoters is coordinately regulated. , 1994, The Journal of biological chemistry.

[17]  G. Basso,et al.  Mono- and bi-allelic expression of insulin-like growth factor II gene in human muscle tumors. , 1994, Human molecular genetics.

[18]  W. Gerald,et al.  Epigenetic lesions at the H19 locus in Wilms' tumour patients , 1994, Nature Genetics.

[19]  A. Feinberg,et al.  Loss of imprinting of IGF2 is linked to reduced expression and abnormal methylation of H19 in Wilms' tumour , 1994, Nature Genetics.

[20]  S. Zhan,et al.  Activation of an imprinted allele of the insulin-like growth factor II gene implicated in rhabdomyosarcoma. , 1994, The Journal of clinical investigation.

[21]  D. Hanahan,et al.  A second signal supplied by insulin-like growth factor II in oncogene-induced tumorigenesis , 1994, Nature.

[22]  Stella M. Davies Developmental regulation of genomic imprinting of the IGF2 gene in human liver. , 1994, Cancer research.

[23]  R. Ueda,et al.  Altered imprinting in lung cancer , 1994, Nature Genetics.

[24]  T. Ekström,et al.  Overlapping patterns of IGF2 and H19 expression during human development: biallelic IGF2 expression correlates with a lack of H19 expression. , 1994, Development.

[25]  M. Eccles,et al.  Constitutional relaxation of insulin–like growth factor II gene imprinting associated with Wilms' tumour and gigantism , 1993, Nature Genetics.

[26]  Benjamin Tycko,et al.  Tumour-suppressor activity of H19 RNA , 1993, Nature.

[27]  R. Weksberg,et al.  Disruption of insulin–like growth factor 2 imprinting in Beckwith–Wiedemann syndrome , 1993, Nature genetics.

[28]  B. Tycko,et al.  Imprinting of human H19: allele-specific CpG methylation, loss of the active allele in Wilms tumor, and potential for somatic allele switching. , 1993, American journal of human genetics.

[29]  A. Feinberg,et al.  Relaxation of imprinted genes in human cancer , 1993, Nature.

[30]  M. Eccles,et al.  Relaxation of insulin-like growth factor II gene imprinting implicated in Wilms' tumour , 1993, Nature.

[31]  F. V. Schaik,et al.  Initial characterization of the four promoters of the human insulin-like growth factor II gene , 1991, Molecular and Cellular Endocrinology.

[32]  C. Junien,et al.  Uniparental paternal disomy in a genetic cancer-predisposing syndrome , 1991, Nature.

[33]  M. Surani,et al.  Embryological and molecular investigations of parental imprinting on mouse chromosome 7 , 1991, Nature.

[34]  M. Pembrey,et al.  Uniparental paternal disomy in Angelman's syndrome , 1991, The Lancet.

[35]  A. Efstratiadis,et al.  Parental imprinting of the mouse insulin-like growth factor II gene , 1991, Cell.

[36]  S. Steinberg,et al.  Insulin-like growth factor II-mediated proliferation of human neuroblastoma. , 1991, The Journal of clinical investigation.

[37]  E. Kohn,et al.  Insulin-like growth factor II acts as an autocrine growth and motility factor in human rhabdomyosarcoma tumors. , 1990, Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research.

[38]  A. Efstratiadis,et al.  A growth-deficiency phenotype in heterozygous mice carrying an insulin-like growth factor II gene disrupted by targeting , 1990, Nature.

[39]  J. Hall,et al.  Genomic imprinting: review and relevance to human diseases. , 1990, American journal of human genetics.

[40]  E. Dees,et al.  The product of the H19 gene may function as an RNA , 1990, Molecular and cellular biology.

[41]  J. Knoll,et al.  Genetic imprinting suggested by maternal heterodisomy in non-deletion Prader-Willi syndrome , 1989, Nature.

[42]  M. Israel,et al.  Autonomous growth of a human neuroblastoma cell line is mediated by insulin-like growth factor II. , 1989, The Journal of clinical investigation.

[43]  R. A. van der Kammen,et al.  The human insulin‐like growth factor II gene contains two development‐specific promoters , 1987, FEBS letters.

[44]  J. Irminger,et al.  Insulin-like growth factor II in human adrenal pheochromocytomas and Wilms tumors: expression at the mRNA and protein level. , 1987, Proceedings of the National Academy of Sciences of the United States of America.

[45]  M. Eccles,et al.  Expression of insulin-like growth factor-II transcripts in Wilms' tumour , 1985, Nature.

[46]  A. Feinberg,et al.  Erratum: Loss of imprinting of IGF2 is linked to reduced expression and abnormal methylation of H19 in Wilms' tumour , 1994, Nature Genetics.