Activation of the interferon system by short-interfering RNAs

[1]  Haibin Xia,et al.  siRNA-mediated gene silencing in vitro and in vivo , 2002, Nature Biotechnology.

[2]  G. Hutvagner,et al.  A microRNA in a Multiple-Turnover RNAi Enzyme Complex , 2002, Science.

[3]  R. Andino,et al.  Short interfering RNA confers intracellular antiviral immunity in human cells , 2002, Nature.

[4]  K. Miyake,et al.  Establishment of a monoclonal antibody against human Toll-like receptor 3 that blocks double-stranded RNA-mediated signaling. , 2002, Biochemical and biophysical research communications.

[5]  O. Donzé,et al.  RNA interference in mammalian cells using siRNAs synthesized with T7 RNA polymerase. , 2002, Nucleic acids research.

[6]  G. Hannon RNA interference : RNA , 2002 .

[7]  M. Stevenson,et al.  Modulation of HIV-1 replication by RNA interference , 2002, Nature.

[8]  R. Flavell,et al.  Recognition of double-stranded RNA and activation of NF-κB by Toll-like receptor 3 , 2001, Nature.

[9]  A. Pasquinelli,et al.  A Cellular Function for the RNA-Interference Enzyme Dicer in the Maturation of the let-7 Small Temporal RNA , 2001, Science.

[10]  T. Tuschl,et al.  Duplexes of 21-nucleotide RNAs mediate RNA interference in cultured mammalian cells , 2001, Nature.

[11]  P. Sharp,et al.  RNAi Double-Stranded RNA Directs the ATP-Dependent Cleavage of mRNA at 21 to 23 Nucleotide Intervals , 2000, Cell.

[12]  Nektarios Tavernarakis,et al.  Heritable and inducible genetic interference by double-stranded RNA encoded by transgenes , 2000, Nature Genetics.

[13]  B. Williams,et al.  PKR; a sentinel kinase for cellular stress , 1999, Oncogene.

[14]  B. Williams,et al.  p38 MAP kinase is required for STAT1 serine phosphorylation and transcriptional activation induced by interferons , 1999, The EMBO journal.

[15]  B. Williams,et al.  Interferon action in triply deficient mice reveals the existence of alternative antiviral pathways. , 1999, Virology.

[16]  G. Stark,et al.  How cells respond to interferons. , 1998, Annual review of biochemistry.

[17]  B. Williams,et al.  Signal transduction in the interferon system. , 1998, Seminars in oncology.

[18]  R. Kaufman,et al.  Phosphorylation of Eukaryotic Translation Initiation Factor 2 Mediates Apoptosis in Response to Activation of the Double-stranded RNA-dependent Protein Kinase* , 1998, The Journal of Biological Chemistry.

[19]  R. Silverman,et al.  Interferon action and apoptosis are defective in mice devoid of 2′,5′‐oligoadenylate‐dependent RNase L , 1997, The EMBO journal.

[20]  R. Silverman 2-5A-Dependent RNase L: A Regulated Endoribonuclease in the Interferon System , 1997 .

[21]  A. Aguzzi,et al.  Deficient signaling in mice devoid of double‐stranded RNA‐dependent protein kinase. , 1995, The EMBO journal.

[22]  Aseem Kumar,et al.  Double-stranded RNA-dependent protein kinase activates transcription factor NF-kappa B by phosphorylating I kappa B. , 1994, Proceedings of the National Academy of Sciences of the United States of America.

[23]  G. Stark,et al.  Use of a selectable marker regulated by alpha interferon to obtain mutations in the signaling pathway , 1989, Molecular and cellular biology.

[24]  I. Kerr,et al.  The respective roles of the protein kinase and pppA2' p5' A2' p5 A-activated endonuclease in the inhibition of protein synthesis by double stranded RNA in rabbit reticulocyte lysates. , 1979, Nucleic acids research.