Elimination of receptor binding by influenza hemagglutinin improves vaccine-induced immunity

[1]  Karlynn E. Neu,et al.  Preexisting immunity shapes distinct antibody landscapes after influenza virus infection and vaccination in humans , 2020, Science Translational Medicine.

[2]  D. Christensen,et al.  Vaccine Adjuvants Differentially Affect Kinetics of Antibody and Germinal Center Responses , 2020, Frontiers in Immunology.

[3]  R. Field,et al.  The SARS-COV-2 Spike Protein Binds Sialic Acids and Enables Rapid Detection in a Lateral Flow Point of Care Diagnostic Device , 2020, ACS central science.

[4]  S. Pillet,et al.  Prime-pull vaccination with a plant-derived virus-like particle influenza vaccine elicits a broad immune response and protects aged mice from death and frailty after challenge , 2019, Immunity & Ageing.

[5]  G. Rimmelzwaan,et al.  Influenza virus-specific CD4+ and CD8+ T cell-mediated immunity induced by infection and vaccination. , 2019, Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology.

[6]  Ji-Yun Kim,et al.  Dual Recognition of Sialic Acid and αGal Epitopes by the VP8* Domains of the Bovine Rotavirus G6P[5] WC3 and of Its Mono-reassortant G4P[5] RotaTeq Vaccine Strains , 2019, Journal of Virology.

[7]  B. Guy,et al.  Immunogenicity and safety of a quadrivalent plant-derived virus like particle influenza vaccine candidate—Two randomized Phase II clinical trials in 18 to 49 and ≥50 years old adults , 2019, PloS one.

[8]  I. Rouiller,et al.  Plant-derived virus-like particle vaccines drive cross-presentation of influenza A hemagglutinin peptides by human monocyte-derived macrophages , 2019, npj Vaccines.

[9]  Kelvin P Lee,et al.  Survival of Long-Lived Plasma Cells (LLPC): Piecing Together the Puzzle , 2019, Front. Immunol..

[10]  John M. Lindner,et al.  Antigen Extraction and B Cell Activation Enable Identification of Rare Membrane Antigen Specific Human B Cells , 2019, Front. Immunol..

[11]  F. Krammer The human antibody response to influenza A virus infection and vaccination , 2019, Nature Reviews Immunology.

[12]  J. Yewdell,et al.  Subdominance and poor intrinsic immunogenicity limit humoral immunity targeting influenza HA stem , 2019, The Journal of clinical investigation.

[13]  P. Kim,et al.  Protect, modify, deprotect (PMD): A strategy for creating vaccines to elicit antibodies targeting a specific epitope , 2018, Proceedings of the National Academy of Sciences.

[14]  G. Gibson,et al.  Factors of the bone marrow microniche that support human plasma cell survival and immunoglobulin secretion , 2018, Nature Communications.

[15]  Sarah Cobey,et al.  Immune History and Influenza Vaccine Effectiveness , 2018, Vaccines.

[16]  I. Rouiller,et al.  Morphological characterization of a plant-made virus-like particle vaccine bearing influenza virus hemagglutinins by electron microscopy. , 2018, Vaccine.

[17]  S. Tangye,et al.  Circulating TFH cells, serological memory, and tissue compartmentalization shape human influenza-specific B cell immunity , 2018, Science Translational Medicine.

[18]  S. Pillet,et al.  The establishment of surrogates and correlates of protection: Useful tools for the licensure of effective influenza vaccines? , 2018, Human vaccines & immunotherapeutics.

[19]  E. Kondrashkina,et al.  Determinant of receptor-preference switch in influenza hemagglutinin. , 2018, Virology.

[20]  S. Pillet,et al.  A Single Intramuscular Dose of a Plant-Made Virus-Like Particle Vaccine Elicits a Balanced Humoral and Cellular Response and Protects Young and Aged Mice from Influenza H1N1 Virus Challenge despite a Modest/Absent Humoral Response , 2017, Clinical and Vaccine Immunology.

[21]  Cheng-Ying Wu,et al.  Plant-made virus-like particle vaccines bearing the hemagglutinin of either seasonal (H1) or avian (H5) influenza have distinct patterns of interaction with human immune cells in vitro. , 2017, Vaccine.

[22]  K. Schughart,et al.  Mutations during the Adaptation of H9N2 Avian Influenza Virus to the Respiratory Epithelium of Pigs Enhance Sialic Acid Binding Activity and Virulence in Mice , 2017, Journal of Virology.

[23]  A. Granados,et al.  Influenza and rhinovirus viral load and disease severity in upper respiratory tract infections. , 2017, Journal of clinical virology : the official publication of the Pan American Society for Clinical Virology.

[24]  S. Carr,et al.  Reconstituted B cell receptor signaling reveals carbohydrate-dependent mode of activation , 2016, Scientific Reports.

[25]  D. Kohda,et al.  Trisaccharide containing α2,3-linked sialic acid is a receptor for mumps virus , 2016, Proceedings of the National Academy of Sciences of the United States of America.

[26]  Nicholas S. Kelley,et al.  Variable influenza vaccine effectiveness by subtype: a systematic review and meta-analysis of test-negative design studies. , 2016, The Lancet. Infectious diseases.

[27]  B. Yassine-Diab,et al.  A plant-derived quadrivalent virus like particle influenza vaccine induces cross-reactive antibody and T cell response in healthy adults. , 2016, Clinical immunology.

[28]  M. Gruber,et al.  An overview of the regulation of influenza vaccines in the United States , 2016, Influenza and other respiratory viruses.

[29]  G. Boivin,et al.  Standardization of Hemagglutination Inhibition Assay for Influenza Serology Allows for High Reproducibility between Laboratories , 2016, Clinical and Vaccine Immunology.

[30]  Zhan-Qiu Yang,et al.  The cytokine storm of severe influenza and development of immunomodulatory therapy , 2015, Cellular and Molecular Immunology.

[31]  M. Shlomchik,et al.  A Temporal Switch in the Germinal Center Determines Differential Output of Memory B and Plasma Cells. , 2014, Immunity.

[32]  C. Verschoor,et al.  Microneutralization Assay Titres Correlate with Protection against Seasonal Influenza H1N1 and H3N2 in Children , 2015, PloS one.

[33]  L. Vézina,et al.  Generation and characterization of a trackable plant‐made influenza H5 virus‐like particle (VLP) containing enhanced green fluorescent protein (eGFP) , 2015, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[34]  B. Yassine-Diab,et al.  Influenza virus-like particle vaccines made in Nicotiana benthamiana elicit durable, poly-functional and cross-reactive T cell responses to influenza HA antigens. , 2014, Clinical immunology.

[35]  Z. Fang,et al.  Human memory T cells from the bone marrow are resting and maintain long-lasting systemic memory , 2014, Proceedings of the National Academy of Sciences.

[36]  T. Mosmann,et al.  Cytokine Diversity in the Th1-Dominated Human Anti-Influenza Response Caused by Variable Cytokine Expression by Th1 Cells, and a Minor Population of Uncommitted IL-2+IFNγ- Thpp Cells , 2014, PloS one.

[37]  Gregory M. Frank,et al.  Flow Cytometry Reveals that H5N1 Vaccination Elicits Cross-Reactive Stem-Directed Antibodies from Multiple Ig Heavy-Chain Lineages , 2014, Journal of Virology.

[38]  E. Kondrashkina,et al.  The roles of hemagglutinin Phe-95 in receptor binding and pathogenicity of influenza B virus. , 2014, Virology.

[39]  H. Holzhausen,et al.  Sialylation and Muscle Performance: Sialic Acid Is a Marker of Muscle Ageing , 2013, PloS one.

[40]  M. Prevost,et al.  Productive Infection of Human Skeletal Muscle Cells by Pandemic and Seasonal Influenza A(H1N1) Viruses , 2013, PloS one.

[41]  Hulin Wu,et al.  Increase in IFNγ−IL-2+ Cells in Recent Human CD4 T Cell Responses to 2009 Pandemic H1N1 Influenza , 2013, PloS one.

[42]  T. Strutt,et al.  Memory CD4+ T cells protect against influenza through multiple synergizing mechanisms. , 2012, The Journal of clinical investigation.

[43]  S. Walmsley,et al.  High-Level Immunogenicity Is Achieved Vaccine With Adjuvanted Pandemic H1N12009 and Improved With Booster Dosing in a Randomized Trial of HIV-Infected Adults , 2012, HIV clinical trials.

[44]  Joe D. Cohen,et al.  Protective Immunity Induced with the RTS,S/AS Vaccine Is Associated with IL-2 and TNF-α Producing Effector and Central Memory CD4+ T Cells , 2011, PloS one.

[45]  Kui-biao Li,et al.  Antibody Dynamics of 2009 Influenza A (H1N1) Virus in Infected Patients and Vaccinated People in China , 2011, PloS one.

[46]  M. Tate,et al.  Correlation between sialic acid expression and infection of murine macrophages by different strains of influenza virus. , 2011, Microbes and infection.

[47]  E. Koay,et al.  Comparison of Pandemic (H1N1) 2009 and Seasonal Influenza Viral Loads, Singapore , 2011, Emerging infectious diseases.

[48]  Y. Zhuo,et al.  Emerging Role of α2,6-Sialic Acid as a Negative Regulator of Galectin Binding and Function* , 2010, The Journal of Biological Chemistry.

[49]  L. Vézina,et al.  The production of hemagglutinin-based virus-like particles in plants: a rapid, efficient and safe response to pandemic influenza. , 2010, Plant biotechnology journal.

[50]  René Ecochard,et al.  Relationship between haemagglutination-inhibiting antibody titres and clinical protection against influenza: development and application of a bayesian random-effects model , 2010, BMC medical research methodology.

[51]  Andreas Radbruch,et al.  Professional memory CD4+ T lymphocytes preferentially reside and rest in the bone marrow. , 2009, Immunity.

[52]  Anna Deplazes,et al.  Piecing together a puzzle , 2009, EMBO reports.

[53]  Brian J Ward,et al.  Influenza virus-like particles produced by transient expression in Nicotiana benthamiana induce a protective immune response against a lethal viral challenge in mice. , 2008, Plant biotechnology journal.

[54]  K. Edwards,et al.  Antibody Responses After Inactivated Influenza Vaccine in Young Children , 2008, The Pediatric infectious disease journal.

[55]  B. Lambrecht,et al.  IL-2 Producing Memory CD4+ T Lymphocytes Are Closely Associated with the Generation of IgG-Secreting Plasma Cells1 , 2008, The Journal of Immunology.

[56]  A. Varki Sialic acids in human health and disease. , 2008, Trends in molecular medicine.

[57]  J. Skehel,et al.  Infectivity Studies of Influenza Virus Hemagglutinin Receptor Binding Site Mutants in Mice , 2008, Journal of Virology.

[58]  C. Bridges,et al.  Immunogenicity and reactogenicity of 1 versus 2 doses of trivalent inactivated influenza vaccine in vaccine-naive 5-8-year-old children. , 2006, The Journal of infectious diseases.

[59]  R. Rappuoli Faculty Opinions recommendation of Protein vaccines induce uncommitted IL-2-secreting human and mouse CD4 T cells, whereas infections induce more IFN-gamma-secreting cells. , 2006 .

[60]  A. Osterhaus,et al.  Haemagglutination-inhibiting antibody to influenza virus. , 2003, Developments in biologicals.

[61]  Xiaolin Zhang,et al.  EFFECTIVENESS , 1977, Prospects for Constitutionalism in Post-Communist Countries.

[62]  J. Skehel,et al.  Receptor binding and membrane fusion in virus entry: the influenza hemagglutinin. , 2000, Annual review of biochemistry.

[63]  J. Skehel,et al.  Studies of the binding properties of influenza hemagglutinin receptor-site mutants. , 1998, Virology.

[64]  R B Couch,et al.  Immunity to influenza in man. , 1983, Annual review of microbiology.

[65]  M. A. Hamilton,et al.  Trimmed Spearman-Karber Method for Estimating Median Lethal Concentrations in Toxicity Bioassays , 1977 .

[66]  R. Bergman A Two-edged Sword , 1975, The Lancet.

[67]  A. S. Beare,et al.  The role of serum haemagglutination-inhibiting antibody in protection against challenge infection with influenza A2 and B viruses , 1972, Epidemiology and Infection.

[68]  W. Stanley THE PREPARATION AND PROPERTIES OF INFLUENZA VIRUS VACCINES CONCENTRATED AND PURIFIED BY DIFFERENTIAL CENTRIFUGATION , 1945, The Journal of experimental medicine.

[69]  T. Francis,et al.  Protective Effect of Vaccination Against Induced Influenza A.∗ , 1944, The Journal of clinical investigation.