Aminoacyl-tRNA synthetases: Current opinion in structural biology 1992, 2:138…-142

Abstract The comparative analysis of structure-function relationships between the two classes of aminoacyl-tRNA synthetase has been made possible by the recent structure determination of the complex of aspartyl-tRNA and aspartyl-tRNA synthetase from yeast, a class-II system. In addition, a refined structure of the Escherichia coli glutaminyl system, a member of the class-I family, has revealed the structural details of anticodon recognition.

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