The Value of Magnetocardiography in Patients with and Without Relevant Stenoses of the Coronary Arteries Using an Unshielded System

Background: The diagnostic management of patients with chest pain remains a clinical challenge. Magnetocardiography (MCG) is a noninvasive method for the recording of cardiac electromagnetic signals at multiple sites above the chest cage. Contrary to electrocardiogram (ECG) the magnetic field is unaltered by surrounding tissues. The present study aimed to analyze the diagnostic value of an unshielded four‐channel MCG for the detection of coronary artery disease (CAD) in patients with chest pain.

[1]  M. Simoons,et al.  Estimation of the Probability of Exercise-induced Ischemia by Quantitative ECG Analysis , 1977, Circulation.

[2]  D Stilli,et al.  Body surface potential mapping in ischemic patients with normal resting ECG. , 1986, The Canadian journal of cardiology.

[3]  R. Kloner,et al.  Altered myocardial states. The stunned and hibernating myocardium. , 1989, The American journal of medicine.

[4]  F. Witkowski,et al.  The clinical utility of body surface potential mapping in coronary artery disease. , 1989, The American journal of cardiology.

[5]  F. Witkowski,et al.  Exercise body surface potential mapping in single and multiple coronary artery disease. , 1990, Chest.

[6]  G. Stroink,et al.  Complementary nature of electrocardiographic and magnetocardiographic data in patients with ischemic heart disease. , 1990, Journal of electrocardiology.

[7]  O Kittnar,et al.  Repolarization pattern of body surface potential maps (BSPM) in coronary artery disease. , 1993, Physiological research.

[8]  Guidelines for cardiac exercise testing. ESC Working Group on Exercise Physiology, Physiopathology and Electrocardiography. , 1993, European heart journal.

[9]  B. Zaret,et al.  Nuclear cardiology (1). , 1993, The New England journal of medicine.

[10]  J. Nenonen.  Solving the inverse problem in magnetocardiography , 1994, IEEE Engineering in Medicine and Biology Magazine.

[11]  M. Starling,et al.  Arbutamine echocardiography: efficacy and safety of a new pharmacologic stress agent to induce myocardial ischemia and detect coronary artery disease. The International Arbutamine Study Group. , 1995, Journal of the American College of Cardiology.

[12]  H Schmidt-Kloiber,et al.  [Measuring optical tissue data using pulsed photoacoustic spectroscopy (PPAS)]. , 1997, Biomedizinische Technik. Biomedical engineering.

[13]  W Grechenig,et al.  [Value of ultrasound of the support and locomotor system--with special reference to radiation exposure and cost reduction]. , 1997, Biomedizinische Technik. Biomedical engineering.

[14]  R S MacLeod,et al.  A possible mechanism for electrocardiographically silent changes in cardiac repolarization. , 1998, Journal of electrocardiology.

[15]  S. Lange,et al.  Coronary Artery Disease May Alter the Spatial Dispersion of the QT Interval at Rest , 1999 .

[16]  A. Schmermund,et al.  Potential and pitfalls of electron-beam computed tomography in detecting coronary atherosclerosis , 1999, Basic Research in Cardiology.

[17]  J. Rumberger,et al.  Probabilistic model for prediction of angiographically defined obstructive coronary artery disease using electron beam computed tomography calcium score strata. , 2000, Circulation.

[18]  René M. Botnar,et al.  Coronary magnetic resonance angiography for the detection of coronary stenoses. , 2001, The New England journal of medicine.

[19]  A. Kandori,et al.  Detection of myocardial ischemia by magnetocardiogram using 64-channel SQUID system , 2001 .

[20]  Jukka Nenonen,et al.  Recording locations in multichannel magnetocardiography and body surface potential mapping sensitive for regional exercise-induced myocardial ischemia , 2001, Basic Research in Cardiology.

[21]  J Knuuti,et al.  Current-density estimation of exercise-induced ischemia in patients with multivessel coronary artery disease. , 2001, Journal of electrocardiology.

[22]  H. Koch.  SQUID magnetocardiography: status and perspectives , 2001 .

[23]  M. Schwaiger,et al.  Positionsbericht nuklearkardiologische Diagnostik – Update , 2002, Zeitschrift für Kardiologie.

[24]  Jukka Nenonen,et al.  Features of ST segment and T-wave in exercise-induced myocardial ischemia evaluated with multichannel magnetocardiography , 2002, Annals of medicine.

[25]  Riccardo Fenici,et al.  First 36-Channel Magnetocardiographic Study of CAD Patients in an Unshielded Laboratory for Interventional and Intensive Cardiac Care , 2003, FIMH.

[26]  Birgit Hailer,et al.  Magnetocardiography in coronary artery disease with a new system in an unshielded setting , 2003, Clinical cardiology.

[27]  D. Grönemeyer,et al.  Spatial Distribution of Repolarization Times in Patients with Coronary Artery Disease , 2003, Pacing and clinical electrophysiology : PACE.

[28]  Riccardo Fenici,et al.  First 36-channel System for Clinical Magnetocardiography in Unshielded Hospital Laboratory for Cardiac Electrophysiology. , 2003 .

[29]  Iwao Yamaguchi,et al.  An iso-integral mapping technique using magnetocardiogram, and its possible use for diagnosis of ischemic heart disease , 2000, The International Journal of Cardiac Imaging.

[30]  J. Tardif,et al.  Reliability of mechanical and phased-array designs for serial intravascular ultrasound examinations , 2000, The International Journal of Cardiac Imaging.

[31]  Jukka Nenonen,et al.  Magnetocardiographic and Electrocardiographic Exercise Mapping in Healthy Subjects , 2001, Annals of Biomedical Engineering.

[32]  K. Magnusson,et al.  Mechanical manipulation of polymorphonuclear leukocyte plasma membranes with optical tweezers causes influx of extracellular calcium through membrane channels , 1999, Medical & Biological Engineering & Computing.

[33]  R. Ilmoniemi,et al.  Minimum-norm estimation in a boundary-element torso model , 2006, Medical and Biological Engineering and Computing.