Future Perspectives: Therapeutic Targeting of Notch Signalling May Become a Strategy in Patients Receiving Stem Cell Transplantation for Hematologic Malignancies
暂无分享,去创建一个
Håkon Reikvam | Øystein Bruserud | Ø. Bruserud | H. Reikvam | E. Ersvaer | K. Hatfield | Elisabeth Ersvaer | Kimberley J. Hatfield
[1] Raymond E. Moellering,et al. Direct inhibition of the NOTCH transcription factor complex , 2010, Nature.
[2] Rajendran Sanalkumar,et al. Non-canonical activation of Notch signaling/target genes in vertebrates , 2010, Cellular and Molecular Life Sciences.
[3] I. Screpanti,et al. Notch signaling and diseases: an evolutionary journey from a simple beginning to complex outcomes. , 2008, Biochimica et biophysica acta.
[4] H. Macdonald,et al. Notch signaling in the immune system. , 2010, Immunity.
[5] U. Suter,et al. Jagged1-dependent Notch signaling is dispensable for hematopoietic stem cell self-renewal and differentiation. , 2005, Blood.
[6] S. Choi,et al. Acute graft-versus-host disease: new treatment strategies , 2009, Current opinion in hematology.
[7] M. Elowitz,et al. Cis Interactions between Notch and Delta Generate Mutually Exclusive Signaling States , 2010, Nature.
[8] N. Nara,et al. Expression of Notchl and Jaggedl Proteins in Acute Myeloid Leukemia Cells , 2001 .
[9] A. Sengupta,et al. Deregulation and cross talk among Sonic hedgehog, Wnt, Hox and Notch signaling in chronic myeloid leukemia progression , 2007, Leukemia.
[10] R. Moon,et al. Glycogen synthase kinase-3 is an in vivo regulator of hematopoietic stem cell repopulation , 2006, Nature Medicine.
[11] Brendan H. Lee,et al. Dimorphic effects of Notch signaling in bone homeostasis , 2008, Nature Medicine.
[12] Franco Locatelli,et al. Cotransplantation of ex vivo expanded mesenchymal stem cells accelerates lymphocyte recovery and may reduce the risk of graft failure in haploidentical hematopoietic stem-cell transplantation. , 2007, Blood.
[13] F. Staal,et al. Wnt signaling in hematopoiesis: Crucial factors for self‐renewal, proliferation, and cell fate decisions , 2010, Journal of cellular biochemistry.
[14] H. Niwa,et al. Wnt Signaling Regulates Hemopoiesis Through Stromal Cells1 , 2001, The Journal of Immunology.
[15] C. Osipo,et al. Notch versus the proteasome: what is the target of γ-secretase inhibitor-I? , 2009, Breast Cancer Research.
[16] C. Viscoli,et al. Bacterial infection prevention after hematopoietic cell transplantation , 2009, Bone Marrow Transplantation.
[17] M. Shimada,et al. Notch2 Signaling Is Required for Potent Antitumor Immunity In Vivo , 2010, The Journal of Immunology.
[18] J. Wagner,et al. Successful immune reconstitution decreases leukemic relapse and improves survival in recipients of unrelated cord blood transplantation. , 2006, Biology of blood and marrow transplantation : journal of the American Society for Blood and Marrow Transplantation.
[19] R. Alloway,et al. Proteasome inhibition for antibody-mediated rejection , 2009, Current opinion in organ transplantation.
[20] J. Aster,et al. Canonical notch signaling is dispensable for the maintenance of adult hematopoietic stem cells. , 2005, Cell stem cell.
[21] M. Bhatia,et al. Novel roles for Notch, Wnt and Hedgehog in hematopoesis derived from human pluripotent stem cells. , 2010, The International journal of developmental biology.
[22] A. Ferrando,et al. CUTLL1, a novel human T-cell lymphoma cell line with t(7;9) rearrangement, aberrant NOTCH1 activation and high sensitivity to γ-secretase inhibitors , 2006, Leukemia.
[23] B. Sandmaier,et al. Transmission and expansion of HOXB4-induced leukemia in two immunosuppressed dogs: implications for a new canine leukemia model. , 2009, Experimental hematology.
[24] N. Gray,et al. FLT3 inhibition and mechanisms of drug resistance in mutant FLT3-positive AML. , 2009, Drug resistance updates : reviews and commentaries in antimicrobial and anticancer chemotherapy.
[25] L. Calvi,et al. Notch signaling and the bone marrow hematopoietic stem cell niche. , 2010, Bone.
[26] N. Nara,et al. Expression of Notch1 and Jagged1 proteins in acute myeloid leukemia cells. , 2001, Leukemia & lymphoma.
[27] M. Dettke,et al. Notch2 is involved in the overexpression of CD23 in B-cell chronic lymphocytic leukemia. , 2002, Blood.
[28] A. Capobianco,et al. Perturbation of Ikaros isoform selection by MLV integration is a cooperative event in Notch(IC)-induced T cell leukemogenesis. , 2003, Cancer cell.
[29] J. Aster,et al. Separation of Notch1 Promoted Lineage Commitment and Expansion/Transformation in Developing T Cells , 2001, The Journal of experimental medicine.
[30] S. Sone,et al. Notch2 integrates signaling by the transcription factors RBP-J and CREB1 to promote T cell cytotoxicity , 2008, Nature Immunology.
[31] Sruthi K. Swaminathan,et al. Cortical neural precursors inhibit their own differentiation via N-cadherin maintenance of beta-catenin signaling. , 2010, Developmental cell.
[32] M. Turner,et al. Thymic development beyond β-selection requires phosphatidylinositol 3-kinase activation by CXCR4 , 2010, The Journal of experimental medicine.
[33] Y. Wang,et al. Expression analysis of Notch-related molecules in peripheral blood T helper cells of patients with rheumatoid arthritis , 2010, Scandinavian journal of rheumatology.
[34] A. Tyndall,et al. Autoimmunity following haematopoietic stem-cell transplantation. , 2007, Best practice & research. Clinical haematology.
[35] S. Ansell,et al. Early lymphocyte recovery predicts superior survival after autologous hematopoietic stem cell transplantation in multiple myeloma or non-Hodgkin lymphoma. , 2001, Blood.
[36] Ø. Bruserud,et al. Targeted therapy in acute myeloid leukaemia: current status and future directions. , 2009, Expert opinion on investigational drugs.
[37] Leslie L Robison,et al. Acute lymphoblastic leukaemia , 2018, Radiopaedia.org.
[38] Tatsuya Kobayashi,et al. Notch signaling maintains bone marrow mesenchymal progenitors by suppressing osteoblast differentiation , 2008, Nature Medicine.
[39] A. Tyndall,et al. Chronic GVHD as an autoimmune disease. , 2008, Best practice & research. Clinical haematology.
[40] J. Aster,et al. c-Myc is an important direct target of Notch1 in T-cell acute lymphoblastic leukemia/lymphoma. , 2006, Genes & development.
[41] Ø. Bruserud,et al. Biological treatment in acute myelogenous leukaemia: how should T-cell targeting immunotherapy be combined with intensive chemotherapy? , 2001, Expert opinion on biological therapy.
[42] R. Alloway,et al. Proteasome inhibition reduces donor-specific antibody levels. , 2009, Transplantation proceedings.
[43] N. Schmitz,et al. Autografting of highly purified peripheral blood progenitor cells following myeloablative therapy in patients with lymphoma: a prospective study of the long-term effects on tumor eradication, reconstitution of hematopoiesis and immune recovery , 1999, Bone Marrow Transplantation.
[44] C. Rooney,et al. Induction of Antigen-Specific Regulatory T Cells following Overexpression of a Notch Ligand by Human B Lymphocytes , 2003, Journal of Virology.
[45] S. Fricker,et al. CXCR4 in clinical hematology. , 2010, Current topics in microbiology and immunology.
[46] Ø. Bruserud,et al. Early pre-engraftment, functional, in vitro responsiveness of T lymphocytes in allotransplanted, acute leukemia patients: proliferation and release of a broad profile of cytokines, possibly predictive of graft-versus-host disease. , 2010, European cytokine network.
[47] J. Vose,et al. Rapid immunologic reconstitution following transplantation with mobilized peripheral blood stem cells as compared to bone marrow , 1997, Bone Marrow Transplantation.
[48] J. Sklar,et al. TAN-1, the human homolog of the Drosophila Notch gene, is broken by chromosomal translocations in T lymphoblastic neoplasms , 1991, Cell.
[49] N. Copeland,et al. Molecular genetic characterization of six recessive viable alleles of the mouse agouti locus. , 1995, Genetics.
[50] J. Storek. Immunological reconstitution after hematopoietic cell transplantation - its relation to the contents of the graft. , 2008, Expert Opinion on Biological Therapy.
[51] D. Prockop,et al. Minimal criteria for defining multipotent mesenchymal stromal cells. The International Society for Cellular Therapy position statement. , 2006, Cytotherapy.
[52] Hua Han,et al. Notch signaling maintains proliferation and survival of the HL60 human promyelocytic leukemia cell line and promotes the phosphorylation of the Rb protein , 2010, Molecular and Cellular Biochemistry.
[53] Ø. Bruserud,et al. The chemokine system in experimental and clinical hematology. , 2010, Current topics in microbiology and immunology.
[54] R. Flavell,et al. The different faces of Notch in T-helper-cell differentiation , 2009, Nature Reviews Immunology.
[55] M. Bhatia,et al. The Notch Ligand Jagged-1 Represents a Novel Growth Factor of Human Hematopoietic Stem Cells , 2000, The Journal of experimental medicine.
[56] Complexity of CEBPA Dysregulation in Human Acute Myeloid Leukemia , 2009, Clinical Cancer Research.
[57] O. Ringdén,et al. Immunomodulation by mesenchymal stem cells and clinical experience , 2007, Journal of internal medicine.
[58] T. Golde,et al. Inhibitors of γ-secretase block in vivo and in vitro T helper type 1 polarization by preventing Notch upregulation of Tbx21 , 2005, Nature Immunology.
[59] Yi Tang,et al. TGFbeta/BMP inhibits the bone marrow transformation capability of Hoxa9 by repressing its DNA-binding ability. , 2006, The EMBO journal.
[60] I. Screpanti,et al. Constitutively activated Notch signaling is involved in survival and apoptosis resistance of B-CLL cells. , 2009, Blood.
[61] M. Imamura,et al. Mesenchymal stem cells for treatment and prevention of graft-versus-host disease after allogeneic hematopoietic cell transplantation. , 2009, Current stem cell research & therapy.
[62] E. Montserrat,et al. Kinetics of recovery of dendritic cell subsets after reduced-intensity conditioning allogeneic stem cell transplantation and clinical outcome , 2007, Haematologica.
[63] Mark J. Murphy,et al. c-Myc controls the balance between hematopoietic stem cell self-renewal and differentiation. , 2004, Genes & development.
[64] H. Einsele,et al. Viral disease prevention after hematopoietic cell transplantation , 2009, Bone Marrow Transplantation.
[65] R. Verhaak,et al. Prognostically useful gene-expression profiles in acute myeloid leukemia. , 2004, The New England journal of medicine.
[66] Ping Ji,et al. Translocation Products in Acute Myeloid Leukemia Activate the Wnt Signaling Pathway in Hematopoietic Cells , 2004, Molecular and Cellular Biology.
[67] H. Dombret,et al. NOTCH1/FBXW7 mutation identifies a large subgroup with favorable outcome in adult T-cell acute lymphoblastic leukemia (T-ALL): a Group for Research on Adult Acute Lymphoblastic Leukemia (GRAALL) study. , 2009, Blood.
[68] Andrew P. Weng,et al. Activating Mutations of NOTCH1 in Human T Cell Acute Lymphoblastic Leukemia , 2004, Science.
[69] J. Falkenburg,et al. Mesenchymal stem cells promote engraftment of human umbilical cord blood-derived CD34(+) cells in NOD/SCID mice. , 2002, Experimental hematology.
[70] P. Kivisäkk,et al. Jagged1 and Delta1 Differentially Regulate the Outcome of Experimental Autoimmune Encephalomyelitis1 , 2007, The Journal of Immunology.
[71] A. F. Campese,et al. Expression of Activated Notch3 in Transgenic Mice Enhances Generation of T Regulatory Cells and Protects against Experimental Autoimmune Diabetes1 , 2003, The Journal of Immunology.
[72] K. Ross,et al. Characterization of Notch1 Antibodies That Inhibit Signaling of Both Normal and Mutated Notch1 Receptors , 2010, PloS one.
[73] N. Manley,et al. Delta-like 4 is the essential, nonredundant ligand for Notch1 during thymic T cell lineage commitment , 2008, The Journal of experimental medicine.
[74] E. Srour,et al. Impact of interactions of cellular components of the bone marrow microenvironment on hematopoietic stem and progenitor cell function. , 2010, Blood.
[75] D. Tuck,et al. Downstream targets of HOXB4 in a cell line model of primitive hematopoietic progenitor cells. , 2010, Blood.
[76] S. Markovic,et al. Timely reconstitution of immune competence affects clinical outcome following autologous stem cell transplantation , 2004, Clinical and Experimental Medicine.
[77] F. Gao,et al. Notch signaling: a novel regulating differentiation mechanism of human umbilical cord blood-derived mesenchymal stem cells into insulin-producing cells in vitro. , 2010, Chinese medical journal.
[78] I. Maillard,et al. Notch signaling in the hematopoietic system , 2009, Expert opinion on biological therapy.
[79] Göran Karlsson,et al. Signaling pathways governing stem-cell fate. , 2008, Blood.
[80] M. Muckenthaler,et al. Activating NOTCH1 mutations predict favorable early treatment response and long-term outcome in childhood precursor T-cell lymphoblastic leukemia. , 2006, Blood.
[81] Ø. Bruserud,et al. The proteasome inhibitors bortezomib and PR‐171 have antiproliferative and proapoptotic effects on primary human acute myeloid leukaemia cells , 2007, British journal of haematology.
[82] Keisuke Ito,et al. Tie2/Angiopoietin-1 Signaling Regulates Hematopoietic Stem Cell Quiescence in the Bone Marrow Niche , 2004, Cell.
[83] Y. Kanda,et al. Binding of Delta1, Jagged1, and Jagged2 to Notch2 Rapidly Induces Cleavage, Nuclear Translocation, and Hyperphosphorylation of Notch2 , 2000, Molecular and Cellular Biology.
[84] Ø. Bruserud,et al. Nuclear factor-kappaB signaling: a contributor in leukemogenesis and a target for pharmacological intervention in human acute myelogenous leukemia. , 2009, Critical reviews in oncogenesis.
[85] C. Martínez,et al. Immune reconstitution after allogeneic stem cell transplantation with reduced-intensity conditioning regimens , 2007, Leukemia.
[86] Ø. Bruserud,et al. Acute myelogenous leukemia blasts as accessory cells during T lymphocyte activation: possible implications for future therapeutic strategies , 1999, Leukemia.
[87] Zev Rosenwaks,et al. Engraftment and reconstitution of hematopoiesis is dependent on VEGFR2-mediated regeneration of sinusoidal endothelial cells. , 2009, Cell stem cell.
[88] J. Wingard,et al. Fungal infection prevention after hematopoietic cell transplantation , 2009, Bone Marrow Transplantation.
[89] T. Hampton,et al. A carboxy-terminal deletion mutant of Notch1 accelerates lymphoid oncogenesis in E2A-PBX1 transgenic mice , 2000 .
[90] T. Palaga,et al. Defects in Notch1 upregulation upon activation of T Cells from patients with systemic lupus erythematosus are related to lupus disease activity , 2008, Lupus.
[91] Ø. Bruserud,et al. Subclassification of patients with acute myelogenous leukemia based on chemokine responsiveness and constitutive chemokine release by their leukemic cells. , 2007, Haematologica.
[92] S. White,et al. RNAi-mediated chromatin silencing in fission yeast. , 2008, Current topics in microbiology and immunology.
[93] S. Rutz,et al. Cutting Edge: Plasmacytoid Dendritic Cells Induce IL-10 Production in T Cells via the Delta-Like-4/Notch Axis , 2009, The Journal of Immunology.
[94] L. Cosmi,et al. Toll‐Like Receptors 3 and 4 Are Expressed by Human Bone Marrow‐Derived Mesenchymal Stem Cells and Can Inhibit Their T‐Cell Modulatory Activity by Impairing Notch Signaling , 2008, Stem cells.
[95] Jingru Zhang,et al. Aberrant expression of Notch signaling molecules in patients with immune thrombocytopenic purpura , 2010, Annals of Hematology.
[96] N. Copeland,et al. Itch genetically interacts with Notch1 in a mouse autoimmune disease model. , 2006, Human molecular genetics.
[97] C. McGlade,et al. Mammalian Numb Proteins Promote Notch1 Receptor Ubiquitination and Degradation of the Notch1 Intracellular Domain* , 2003, Journal of Biological Chemistry.
[98] Ian A. White,et al. Endothelial cells are essential for the self-renewal and repopulation of Notch-dependent hematopoietic stem cells. , 2010, Cell stem cell.
[99] N. Nara,et al. Diverse effects of the Notch ligands Jagged1 and Delta1 on the growth and differentiation of primary acute myeloblastic leukemia cells. , 2005, Experimental hematology.
[100] T. Fry,et al. Immune reconstitution following hematopoietic progenitor cell transplantation: challenges for the future , 2005, Bone Marrow Transplantation.
[101] D. Scadden,et al. Osteoblastic cells regulate the haematopoietic stem cell niche , 2003, Nature.
[102] K. Selmaj,et al. Notch3 Inhibition in Myelin-Reactive T Cells Down-Regulates Protein Kinase Cθ and Attenuates Experimental Autoimmune Encephalomyelitis1 , 2008, The Journal of Immunology.
[103] S. Kunkel,et al. Regulation of T Cell Activation by Notch Ligand, DLL4, Promotes IL-17 Production and Rorc Activation , 2009, Journal of Immunology.
[104] M. Caligiuri,et al. Activating mutations in NOTCH1 in acute myeloid leukemia and lineage switch leukemias , 2006, Leukemia.
[105] T. Golde,et al. Notch1 and TGFbeta1 cooperatively regulate Foxp3 expression and the maintenance of peripheral regulatory T cells. , 2008, Blood.
[106] I. Weissman,et al. A role for Wnt signalling in self-renewal of haematopoietic stem cells , 2003, Nature.
[107] G. Neale,et al. Hemgn is a direct transcriptional target of HOXB4 and induces expansion of murine myeloid progenitor cells. , 2010, Blood.
[108] J. Aster,et al. Modulation of Notch Signaling by Antibodies Specific for the Extracellular Negative Regulatory Region of NOTCH3* , 2008, Journal of Biological Chemistry.
[109] S. Rafii,et al. The bone marrow vascular niche: home of HSC differentiation and mobilization. , 2005, Physiology.
[110] L. Chatenoud,et al. Jagged2-expressing hematopoietic progenitors promote regulatory T cell expansion in the periphery through notch signaling. , 2006, Immunity.
[111] D. Rowe,et al. Hematopoiesis is severely altered in mice with an induced osteoblast deficiency. , 2004, Blood.
[112] H. Hirai,et al. Physical interaction of Delta1, Jagged1, and Jagged2 with Notch1 and Notch3 receptors. , 2000, Biochemical and biophysical research communications.
[113] A. Cuneo,et al. Dendritic cell recovery after allogeneic stem‐cell transplantation in acute leukemia: correlations with clinical and transplant characteristics , 2004, European journal of haematology.
[114] Pu Zhang,et al. Distinct gene expression profiles of acute myeloid/T-lymphoid leukemia with silenced CEBPA and mutations in NOTCH1. , 2007, Blood.
[115] H. Mayani,et al. Clinical relevance of NK, NKT, and dendritic cell dose in patients receiving G-CSF-mobilized peripheral blood allogeneic stem cell transplantation , 2006, Annals of Hematology.
[116] J. Aster,et al. A phase I clinical trial of the notch inhibitor MK-0752 in patients with T-cell acute lymphoblastic leukemia/lymphoma (T-ALL) and other leukemias. , 2006, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.
[117] Haiyang Huang,et al. Identification of the haematopoietic stem cell niche and control of the niche size , 2003, Nature.
[118] T. Hampton,et al. A carboxy-terminal deletion mutant of Notch1 accelerates lymphoid oncogenesis in E2A-PBX1 transgenic mice. , 2000, Blood.
[119] Shahin Rafii,et al. Instructive role of the vascular niche in promoting tumour growth and tissue repair by angiocrine factors , 2010, Nature Reviews Cancer.
[120] I. Bernstein,et al. Jagged2 acts as a Delta-like Notch ligand during early hematopoietic cell fate decisions. , 2011, Blood.
[121] M. Gering,et al. Hey2 acts upstream of Notch in hematopoietic stem cell specification in zebrafish embryos. , 2010, Blood.
[122] T. Golde,et al. Targeting Notch to Target Cancer Stem Cells , 2010, Clinical Cancer Research.
[123] Jin-Hwang Liu,et al. Down-regulation of Notch-1 expression decreases PU.1-mediated myeloid differentiation signaling in acute myeloid leukemia. , 1992, International journal of oncology.
[124] M. Zasloff,et al. The nervous system and innate immunity: the neuropeptide connection. , 2005, Nature immunology.
[125] Thijs J. Hagenbeek,et al. Therapeutic antibody targeting of individual Notch receptors , 2010, Nature.
[126] M. Kyba,et al. ER71 acts downstream of BMP, Notch, and Wnt signaling in blood and vessel progenitor specification. , 2008, Cell stem cell.
[127] Michael F Clarke,et al. DLL4 blockade inhibits tumor growth and reduces tumor-initiating cell frequency. , 2009, Cell stem cell.
[128] L. Zon,et al. Genetic Interaction of PGE2 and Wnt Signaling Regulates Developmental Specification of Stem Cells and Regeneration , 2009, Cell.
[129] A. Galy,et al. Recovery of lymphocyte and dendritic cell subsets after autologous CD34+ cell transplantation , 2000, Bone Marrow Transplantation.
[130] Tannishtha Reya,et al. Integration of Notch and Wnt signaling in hematopoietic stem cell maintenance , 2005, Nature Immunology.
[131] J. L. de la Pompa,et al. RBPjκ-dependent Notch function regulates Gata2 and is essential for the formation of intra-embryonic hematopoietic cells , 2005 .
[132] Claire Schwab,et al. Acute lymphoblastic leukaemia. , 2011, Methods in molecular biology.
[133] C. Begley,et al. NOTCH1 pathway activation is an early hallmark of SCL T leukemogenesis. , 2007, Blood.
[134] Ø. Bruserud,et al. Targeting the angiopoietin (Ang)/Tie-2 pathway in the crosstalk between acute myeloid leukaemia and endothelial cells: studies of Tie-2 blocking antibodies, exogenous Ang-2 and inhibition of constitutive agonistic Ang-1 release , 2010, Expert opinion on investigational drugs.
[135] P. Amrolia,et al. Overexpression of the Notch ligand, Jagged-1, induces alloantigen-specific human regulatory T cells. , 2003, Blood.
[136] K. Irvine,et al. Glycosylation regulates Notch signalling , 2003, Nature Reviews Molecular Cell Biology.
[137] Richard A Flavell,et al. Instruction of Distinct CD4 T Helper Cell Fates by Different Notch Ligands on Antigen-Presenting Cells , 2004, Cell.
[138] J. Passweg,et al. Reconstitution of the immune system after hematopoietic stem cell transplantation in humans , 2008, Seminars in Immunopathology.
[139] B. Osborne,et al. Notch-1 Regulates NF-κB Activity in Hemopoietic Progenitor Cells1 , 2001, The Journal of Immunology.
[140] N. Lee,et al. Rapid helper T-cell recovery above 200 × 106/l at 3 months correlates to successful transplant outcomes after allogeneic stem cell transplantation , 2006, Bone Marrow Transplantation.
[141] L. Fu,et al. NOTCH1 mutations are rare in acute myeloid leukemia , 2006, Leukemia & lymphoma.
[142] P. Genever,et al. Regulation of mesenchymal stem cell activity by endothelial cells. , 2011, Stem cells and development.
[143] T. Golde,et al. Notch Regulates Cytolytic Effector Function in CD8+ T Cells1 , 2009, Journal of Immunology.
[144] P. Secchiero,et al. Nutlin-3 up-regulates the expression of Notch1 in both myeloid and lymphoid leukemic cells, as part of a negative feedback antiapoptotic mechanism. , 2009, Blood.
[145] N. Manley,et al. Delta-like 4 is the essential, nonredundant ligand for Notch1 during thymic T cell lineage commitment , 2008 .
[146] J. Lamb,et al. Serrate1-induced notch signalling regulates the decision between immunity and tolerance made by peripheral CD4(+) T cells. , 2000, International immunology.
[147] Colleen Delaney,et al. Notch-mediated expansion of human cord blood progenitor cells capable of rapid myeloid reconstitution , 2010, Nature Medicine.
[148] S. Morrison,et al. Supplemental Experimental Procedures , 2022 .