Successful resection of giant abdominal hemophilic pseudotumor

Abstract Giant abdominal hemophilic pseudotumor is exceedingly rare, thus may bring great challenges to the timely and proper diagnosis and treatment of clinicians. The only definitive management is complete removal of the abdominal hemophilic pseudotumor. The objective of this article is to report surgical treatment and follow-up outcomes of three unusual cases with giant abdominal hemophilic pseudotumor. We describe 3 patients with giant hemophilic pseudotumor involving the abdomen who were successfully treated with tumor resection. On presentation to our institution, the patients all had signs of giant cystic lesions in abdomen, and the patients’ most outstanding complaints were aggravated abdominal pain. All of three patients underwent complete excision of abdominal hemophilic pseudotumor. The patients showed adequate pain relief compared with the previous status. Surgical resection is the most effective treatment option for patients with giant abdominal hemophilic pseudotumor who can undergo appropriate surgical treatment. This represents a safe and reasonable approach to sustainably relieve pain and other symptoms with giant hemophilic pseudotumor in the abdomen. Perioperative coagulation factor replacement therapy is also of great significance in reducing the risks and complications.

[1]  Xiaoping Zhou,et al.  Surgical Management of Haemophilic Pseudotumors: Experience in a Developing Country , 2019, Journal of investigative surgery : the official journal of the Academy of Surgical Research.

[2]  X. Weng,et al.  Surgical Treatment for Hemophilic Pseudotumor: Twenty-three Cases with an Average Follow-up of 5 Years , 2017, The Journal of bone and joint surgery. American volume.

[3]  K. Kai,et al.  Nasal hemophilic pseudotumor in a patient with mild hemophilia A and allergic rhinitis , 2017, Pediatrics international : official journal of the Japan Pediatric Society.

[4]  M. Duarte,et al.  Hemophilic pseudotumor – a rare complication , 2016, Revista brasileira de hematologia e hemoterapia.

[5]  H. Kato,et al.  Complete bone regeneration in hemophilic pseudotumor of the mandible , 2016, Pediatrics international : official journal of the Japan Pediatric Society.

[6]  E. Coche,et al.  CT and MRI Aspects of an Abdominal Hemophilic Pseudotumor , 2015, Journal of the Belgian Society of Radiology.

[7]  A. Livingston,et al.  A Pelvic Pseudotumor in a Nonhemophilic Patient: An Unusual Presentation , 2015, Case reports in hematology.

[8]  C. Anderson,et al.  Hemophilic Pseudotumor: An Important Differential Diagnosis of an Intracranial Mass. , 2015, Journal of pediatric hematology/oncology.

[9]  C. Hermans,et al.  Successful emergency resection of a massive intra-abdominal hemophilic pseudotumor. , 2015, World journal of gastrointestinal surgery.

[10]  X. Weng,et al.  Surgical management of hemophilic pseudotumor complicated by destructive osteoarthropathy , 2015, Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis.

[11]  J. Arockiaraj,et al.  Hemophilic pseudotumor of the first lumbar vertebra , 2014, Indian journal of orthopaedics.

[12]  J. López-Gómez,et al.  Management of the hemophilic pseudotumor of the abdomen: A rare pathological entity , 2014, International journal of surgery case reports.

[13]  Qingsheng Xu,et al.  Bilateral Cranial Hemophilic Pseudotumor , 2014, The Journal of craniofacial surgery.

[14]  Radheshyam Purkait,et al.  Nasal hemophilic pseudotumor: Favorable response to radiotherapy , 2013, Indian Pediatrics.

[15]  Chien-Lin Liu,et al.  Pelvic hemophilic pseudotumor presenting as severe sciatic pain in a patient with no history of hemophilic symptoms , 2012, Journal of orthopaedic science : official journal of the Japanese Orthopaedic Association.

[16]  M. Gilbert,et al.  Intraosseous pseudotumor of the distal radius in a patient with hemophilia: case report. , 2012, The Journal of hand surgery.

[17]  D. Baker,et al.  Pseudotumor of hemophilia in the mandible of a patient with hemophilia A. , 2012, Oral surgery, oral medicine, oral pathology and oral radiology.

[18]  Lei Zhang,et al.  Hemophilic Pseudotumor in Chinese Patients: A Retrospective Single-Centered Analysis of 14 Cases , 2011 .

[19]  D. Neogi,et al.  Hemophilic pseudotumor--is there a role of radiotherapy? Literature review and a case report. , 2010, Nepal Medical College journal : NMCJ.

[20]  Francisco Sánchez-Bueno,et al.  Pseudotumor hemofílico intraabdominal: A propósito de un caso , 2010 .

[21]  Deok-Won Lee,et al.  Changes in a hemophilic pseudotumor of the mandible that developed over a 20-year period. , 2009, Journal of oral and maxillofacial surgery : official journal of the American Association of Oral and Maxillofacial Surgeons.

[22]  Y. Kilic,et al.  Iliopsoas hemophilic pseudotumor with bowel fistulization. , 2009, Bratislavske lekarske listy.

[23]  W. Coon,et al.  Management of abdominal hemophilic pseudotumor. , 1981, Surgery.