Adult-Onset Autosomal Dominant Leukodystrophy: Linking Nuclear Envelope to Myelin

Adult-onset autosomal dominant leukodystrophy (ADLD) was first described for a large kindred with a progressive and fatal neurological white matter disorder in an American-Irish family ([Eldridge et al., 1984][1]). Subsequently, ADLD has been reported in many other ethnic groups including Japanese,

[1]  E. Benarroch,et al.  Nuclear lamins , 2012, Neurology.

[2]  L. Opitz,et al.  Control of oligodendroglial cell number by the miR-17-92 cluster , 2010, Development.

[3]  P. Flicek,et al.  Molecular maps of the reorganization of genome-nuclear lamina interactions during differentiation. , 2010, Molecular cell.

[4]  E. Gregorio,et al.  A family with autosomal dominant leukodystrophy linked to 5q23.2–q23.3 without lamin B1 mutations , 2010, European journal of neurology.

[5]  K. Nave Oligodendrocytes and the “Micro Brake” of Progenitor Cell Proliferation , 2010, Neuron.

[6]  Michael T. McManus,et al.  Dicer1 and miR-219 Are Required for Normal Oligodendrocyte Differentiation and Myelination , 2010, Neuron.

[7]  Q. Lu,et al.  MicroRNA-Mediated Control of Oligodendrocyte Differentiation , 2010, Neuron.

[8]  H. Worman,et al.  Diseases of the nuclear envelope. , 2010, Cold Spring Harbor perspectives in biology.

[9]  Michael T. McManus,et al.  Dicer ablation in oligodendrocytes provokes neuronal impairment in mice , 2009, Annals of neurology.

[10]  S. Gasser,et al.  The nuclear envelope--a scaffold for silencing? , 2009, Current opinion in genetics & development.

[11]  Ying-Hui Fu,et al.  miR-23 regulation of lamin B1 is crucial for oligodendrocyte development and myelination , 2009, Disease Models & Mechanisms.

[12]  Mauro,et al.  A novel family with Lamin B1 duplication associated with adult-onset leucoencephalopathy , 2009, Journal of Neurology, Neurosurgery, and Psychiatry.

[13]  J. Bouchard,et al.  A novel duplication confirms the involvement of 5q23.2 in autosomal dominant leukodystrophy. , 2008, Archives of neurology.

[14]  L. Notterpek,et al.  Identification of Dynamically Regulated MicroRNA and mRNA Networks in Developing Oligodendrocytes , 2008, The Journal of Neuroscience.

[15]  R. Raininko,et al.  MR Imaging Characteristics and Neuropathology of the Spinal Cord in Adult-Onset Autosomal Dominant Leukodystrophy with Autonomic Symptoms , 2008, American Journal of Neuroradiology.

[16]  L. Wessels,et al.  Domain organization of human chromosomes revealed by mapping of nuclear lamina interactions , 2008, Nature.

[17]  E. Bertolino,et al.  Transcriptional repression mediated by repositioning of genes to the nuclear lamina , 2008, Nature.

[18]  Elizabeth Kerr,et al.  Recruitment to the Nuclear Periphery Can Alter Expression of Genes in Human Cells , 2008, PLoS genetics.

[19]  F. Slack,et al.  Small non-coding RNAs in animal development , 2008, Nature Reviews Molecular Cell Biology.

[20]  C. Sander,et al.  A Mammalian microRNA Expression Atlas Based on Small RNA Library Sequencing , 2007, Cell.

[21]  H. Worman,et al.  "Laminopathies": a wide spectrum of human diseases. , 2007, Experimental cell research.

[22]  R. Foisner,et al.  Lamins and lamin-associated proteins in aging and disease. , 2007, Current opinion in cell biology.

[23]  Chiu Fan Lee,et al.  Defects in lamin B1 expression or processing affect interphase chromosome position and gene expression , 2007, The Journal of cell biology.

[24]  T. Speed,et al.  Functional Genomic Analysis of Oligodendrocyte Differentiation , 2006, The Journal of Neuroscience.

[25]  V. Giedraitis,et al.  Adult‐onset autosomal dominant leukodystrophy with autonomic symptoms restricted to 1.5 Mbp on chromosome 5q23 , 2006, American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics.

[26]  R. Schiffmann,et al.  Lamin B1 duplications cause autosomal dominant leukodystrophy , 2006, Nature Genetics.

[27]  M. Fornerod,et al.  Characterization of the Drosophila melanogaster genome at the nuclear lamina , 2006, Nature Genetics.

[28]  R. Raininko,et al.  MR characteristics and neuropathology in adult-onset autosomal dominant leukodystrophy with autonomic symptoms. , 2006, AJNR. American journal of neuroradiology.

[29]  Ken Inoue PLP1-related inherited dysmyelinating disorders: Pelizaeus-Merzbacher disease and spastic paraplegia type 2 , 2005, Neurogenetics.

[30]  G. Krohne,et al.  The lamin CxxM motif promotes nuclear membrane growth , 2004, Journal of Cell Science.

[31]  C. Grund,et al.  Intranuclear membrane structure formations by CaaX-containing nuclear proteins , 2004, Journal of Cell Science.

[32]  M. Bergo,et al.  Lamin B1 is required for mouse development and nuclear integrity. , 2004, Proceedings of the National Academy of Sciences of the United States of America.

[33]  D. Bartel MicroRNAs Genomics, Biogenesis, Mechanism, and Function , 2004, Cell.

[34]  Oliver Hobert,et al.  A microRNA controlling left/right neuronal asymmetry in Caenorhabditis elegans , 2003, Nature.

[35]  H. Lassmann,et al.  Endoplasmic Reticulum Stress in PLP‐Overexpressing Transgenic Rats: Gray Matter Oligodendrocytes Are More Vulnerable than White Matter Oligodendrocytes , 2002, Journal of neuropathology and experimental neurology.

[36]  A. Koeppen,et al.  Genetic localization of an autosomal dominant leukodystrophy mimicking chronic progressive multiple sclerosis to chromosome 5q31. , 2000, Human molecular genetics.

[37]  G. Vaula,et al.  MRI and CT in an autosomal-dominant, adult-onset leukodystrophy , 1997, Neuroradiology.

[38]  Takurou Kobayashi,et al.  [A Japanese family with probably autosomal dominant adult-onset leukodystrophy]. , 1996, Rinsho shinkeigaku = Clinical neurology.

[39]  H. Osaka,et al.  A duplicated PLP gene causing Pelizaeus-Merzbacher disease detected by comparative multiplex PCR. , 1996, American journal of human genetics.

[40]  H. McFarland,et al.  Clinical and pathological features of an autosomal dominant, adult-onset leukodystrophy simulating chronic progressive multiple sclerosis. , 1994, Archives of neurology.

[41]  N. Patronas,et al.  Computed tomography and magnetic resonance imaging in adult-onset leukodystrophy. , 1988, Archives of neurology.

[42]  C. Bever,et al.  Hereditary adult-onset leukodystrophy simulating chronic progressive multiple sclerosis. , 1984, The New England journal of medicine.

[43]  G. Krohne,et al.  The nuclear lamins. A multigene family of proteins in evolution and differentiation. , 1986, Experimental cell research.