Treatment of non‐tuberculous mycobacterial cervicofacial lymphadenitis in children: critical appraisal of the literature

Background:  Surgical excision has historically been the treatment of choice for non‐tuberculous mycobacterial cervicofacial lymphadenitis. Emerging data suggests antibiotic treatment alone could be an attractive alternative to surgery. We questioned (1) what treatment offers best cure rates in children with this condition and (2) the evidence for antibiotic treatment alone.

[1]  W. Assendelft,et al.  Inleiding in evidence-based medicine : klinisch handelen gebaseerd op bewijsmateriaal , 2008 .

[2]  J. Prins,et al.  Surgical excision versus antibiotic treatment for nontuberculous mycobacterial cervicofacial lymphadenitis in children: a multicenter, randomized, controlled trial. , 2007, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

[3]  H. Jafri,et al.  Antibiotic Therapy for Nontuberculous Mycobacterial Cervicofacial Lymphadenitis , 2005, The Laryngoscope.

[4]  A. Loeffler.  Treatment Options for Nontuberculous Mycobacterial Adenitis in Children , 2004, The Pediatric infectious disease journal.

[5]  S. Arend,et al.  Nontuberculous mycobacterial infection in children: a 2-year prospective surveillance study in the Netherlands. , 2004, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

[6]  J. Haddad,et al.  Nontuberculous Mycobacteria‐Induced Parotid Lymphadenitis Successfully Limited With Clarithromycin and Rifabutin , 2004, The Laryngoscope.

[7]  W. Assendelft,et al.  Inleiding in evidence-based medicine , 2003 .

[8]  S. Pransky,et al.  Nontuberculous mycobacterial infections of the head and neck. , 2003, Pediatric clinics of North America.

[9]  E. Wald,et al.  Management of nontuberculous mycobacterial cervical lymphadenitis. , 2003, Archives of otolaryngology--head & neck surgery.

[10]  T. Ottenhoff,et al.  Genetics, cytokines and human infectious disease: lessons from weakly pathogenic mycobacteria and salmonellae , 2002, Nature Genetics.

[11]  P. Jervis,et al.  Management of non-tuberculous mycobacterial peri-sialadenitis in children: the Sheffield otolaryngology experience. , 2001, Clinical otolaryngology and allied sciences.

[12]  B. Currie,et al.  Nontuberculous mycobacterial disease in northern Australia: a case series and review of the literature. , 2000, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

[13]  J. Kimpen,et al.  LYMFADENITIS DOOR NIET-TUBERCULEUZE MYCOBACTERIEN, CHIRURGISCHE OF ANTIBIOTISCHE BEHANDELING ? , 1999 .

[14]  C. Robson,et al.  Lymphadenitis due to nontuberculous mycobacteria in children: presentation and response to therapy. , 1999, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.

[15]  P. Tomà,et al.  Cervical lymphadenitis caused by nontuberculous mycobacteria in immunocompetent children: Clinical and therapeutic experience , 1998, Head & neck.

[16]  D. Nadal,et al.  Treatment of nontuberculous mycobacterial lymphadenitis with clarithromycin plus rifabutin. , 1996, The Journal of pediatrics.

[17]  E. Wolinsky.  Nontuberculous mycobacteria and associated diseases. , 2015, The American review of respiratory disease.