Luminescence switch-on detection of protein tyrosine kinase-7 using a G-quadruplex-selective probe

A novel luminescent G-quadruplex-selective iridium(iii) complex was employed in a G-quadruplex-based detection assay for PTK7.

[1]  G. G. Stokes.  "J." , 1890, The New Yale Book of Quotations.

[2]  Miss A.O. Penney.  (b) , 1974, The New Yale Book of Quotations.

[3]  J. Szostak,et al.  Selection in vitro of single-stranded DNA molecules that fold into specific ligand-binding structures , 1992, Nature.

[4]  C. Hopkins,et al.  Signal-dependent membrane protein trafficking in the endocytic pathway. , 1993, Annual review of cell biology.

[5]  R. Spritz,et al.  A survey of protein tyrosine kinase mRNAs expressed in normal human melanocytes. , 1993, Oncogene.

[6]  H. Lee,et al.  Characterization of the human full-length PTK7 cDNA encoding a receptor protein tyrosine kinase-like molecule closely related to chick KLG. , 1996, Journal of biochemistry.

[7]  T. Rapoport,et al.  Molecular Mechanism of Membrane Protein Integration into the Endoplasmic Reticulum , 1997, Cell.

[8]  R. Spritz,et al.  Loss of expression of receptor tyrosine kinase family genes PTK7 and SEK in metastatic melanoma , 1997, International journal of cancer.

[9]  C. Sanders,et al.  Misfolding of membrane proteins in health and disease: the lady or the tiger? , 2000, Current opinion in structural biology.

[10]  Kevin Barraclough,et al.  I and i , 2001, BMJ : British Medical Journal.

[11]  Michael A. Choti,et al.  A Phosphatase Associated with Metastasis of Colorectal Cancer , 2001, Science.

[12]  A. Ducrest,et al.  Detection of promoter activity by flow cytometric analysis of GFP reporter expression. , 2002, Nucleic acids research.

[13]  Milan N Stojanovic,et al.  Aptamer-based colorimetric probe for cocaine. , 2002, Journal of the American Chemical Society.

[14]  Jeffery T. Davis.  G-quartets 40 years later: from 5'-GMP to molecular biology and supramolecular chemistry. , 2004, Angewandte Chemie.

[15]  T. Rapoport,et al.  A membrane protein complex mediates retro-translocation from the ER lumen into the cytosol , 2004, Nature.

[16]  Paul M. Schneider,et al.  High-Throughput Analysis of Genome-Wide Receptor Tyrosine Kinase Expression in Human Cancers Identifies Potential Novel Drug Targets , 2004, Clinical Cancer Research.

[17]  E. Ruoslahti,et al.  Metadherin, a cell surface protein in breast tumors that mediates lung metastasis. , 2004, Cancer cell.

[18]  M. Tessier-Lavigne,et al.  PTK7/CCK-4 is a novel regulator of planar cell polarity in vertebrates , 2004, Nature.

[19]  Jihwan Song,et al.  Cloning and characterization of the full-length mouse Ptk7 cDNA encoding a defective receptor protein tyrosine kinase. , 2004, Gene.

[20]  Y. Yatabe,et al.  Prognostic model of pulmonary adenocarcinoma by expression profiling of eight genes as determined by quantitative real-time reverse transcriptase polymerase chain reaction. , 2004, Journal of clinical oncology : official journal of the American Society of Clinical Oncology.

[21]  S Tombelli,et al.  Development of biosensors with aptamers as bio-recognition element: the case of HIV-1 Tat protein. , 2004, Biosensors & bioelectronics.

[22]  Kylie L. Gorringe,et al.  Novel regions of chromosomal amplification at 6p21, 5p13, and 12q14 in gastric cancer identified by array comparative genomic hybridization , 2005, Genes, chromosomes & cancer.

[23]  Wonhwa Cho,et al.  Membrane-protein interactions in cell signaling and membrane trafficking. , 2005, Annual review of biophysics and biomolecular structure.

[24]  Samuel Wagner,et al.  Rationalizing membrane protein overexpression. , 2006, Trends in biotechnology.

[25]  D. Shangguan,et al.  Aptamers evolved from live cells as effective molecular probes for cancer study , 2006, Proceedings of the National Academy of Sciences.

[26]  G. Barton,et al.  Emerging roles of pseudokinases. , 2006, Trends in cell biology.

[27]  Razvan Nutiu,et al.  Solid-phase enzyme activity assay utilizing an entrapped fluorescence-signaling DNA aptamer. , 2006, Angewandte Chemie.

[28]  Ying Li,et al.  Aptamers evolved from cultured cancer cells reveal molecular differences of cancer cells in patient samples. , 2007, Clinical chemistry.

[29]  María Jesús Lobo-Castañón,et al.  Modified-RNA aptamer-based sensor for competitive impedimetric assay of neomycin B. , 2007, Journal of the American Chemical Society.

[30]  Fuyou Li,et al.  Cationic iridium(III) complexes for phosphorescence staining in the cytoplasm of living cells. , 2008, Chemical communications.

[31]  Adrian Wiestner,et al.  Unique Cell Surface Expression of Receptor Tyrosine Kinase ROR1 in Human B-Cell Chronic Lymphocytic Leukemia , 2008, Clinical Cancer Research.

[32]  Weihong Tan,et al.  Cell-specific aptamer probes for membrane protein elucidation in cancer cells. , 2008, Journal of proteome research.

[33]  I. Shnitsar,et al.  PTK7 recruits dsh to regulate neural crest migration , 2008, Development.

[34]  Yi Xiao,et al.  i-Motif quadruplex DNA-based biosensor for distinguishing single- and multiwalled carbon nanotubes. , 2009, Journal of the American Chemical Society.

[35]  Eun Jeong Cho,et al.  Applications of aptamers as sensors. , 2009, Annual review of analytical chemistry.

[36]  Itamar Willner,et al.  Aptamer-DNAzyme hairpins for amplified biosensing. , 2009, Analytical chemistry.

[37]  Chunhai Fan,et al.  Inhibition of the in vitro replication of DNA by an aptamer-protein complex in an autonomous DNA machine. , 2009, Chemistry.

[38]  Juewen Liu,et al.  Functional nucleic acid sensors. , 2009, Chemical reviews.

[39]  Weihong Tan,et al.  Mapping receptor density on live cells by using fluorescence correlation spectroscopy. , 2009, Chemistry.

[40]  J. Kaur,et al.  A modified Western blot protocol for enhanced sensitivity in the detection of a membrane protein. , 2009, Analytical biochemistry.

[41]  F. Puppo,et al.  The cell polarity PTK7 receptor acts as a modulator of the chemotherapeutic response in acute myeloid leukemia and impairs clinical outcome. , 2010, Blood.

[42]  A. Strongin,et al.  The Wnt/Planar Cell Polarity Protein-tyrosine Kinase-7 (PTK7) Is a Highly Efficient Proteolytic Target of Membrane Type-1 Matrix Metalloproteinase , 2010, The Journal of Biological Chemistry.

[43]  X. Qu,et al.  DNA loop sequence as the determinant for chiral supramolecular compound G-quadruplex selectivity. , 2010, Journal of medicinal chemistry.

[44]  C. Fan,et al.  Amplified fluorescent recognition of g-quadruplex folding with a cationic conjugated polymer and DNA intercalator. , 2010, ACS applied materials & interfaces.

[45]  Fuyou Li,et al.  Phosphorescent chemosensors based on heavy-metal complexes. , 2010, Chemical Society reviews.

[46]  X. Qu,et al.  A quadruplex-based, label-free, and real-time fluorescence assay for RNase H activity and inhibition. , 2010, Chemistry.

[47]  Fuyou Li,et al.  Phosphorescence imaging of homocysteine and cysteine in living cells based on a cationic iridium(III) complex. , 2010, Inorganic chemistry.

[48]  Anthony D. Keefe,et al.  Aptamers as therapeutics , 2010, Nature Reviews Drug Discovery.

[49]  Xiaohong Fang,et al.  Aptamers generated from cell-SELEX for molecular medicine: a chemical biology approach. , 2010, Accounts of chemical research.

[50]  G. Wagner,et al.  PlexinA1 interacts with PTK7 and is required for neural crest migration. , 2010, Biochemical and biophysical research communications.

[51]  Jean-Louis Mergny,et al.  How long is too long? Effects of loop size on G-quadruplex stability , 2010, Nucleic acids research.

[52]  Danzhou Yang,et al.  c-MYC promoter G-quadruplex formed at the 5′-end of NHE III1 element: insights into biological relevance and parallel-stranded G-quadruplex stability , 2011, Nucleic acids research.

[53]  Tao Li,et al.  Fluorescent silver nanoclusters in hybridized DNA duplexes for the turn-on detection of Hg2+ ions. , 2011, Chemical communications.

[54]  Kemin Wang,et al.  Activatable aptamer probe for contrast-enhanced in vivo cancer imaging based on cell membrane protein-triggered conformation alteration , 2011, Proceedings of the National Academy of Sciences.

[55]  A. Strongin,et al.  Potential Relation of Aberrant Proteolysis of Human Protein Tyrosine Kinase 7 (PTK7) chuzhoi by Membrane Type 1 Matrix Metalloproteinase (MT1-MMP) to Congenital Defects* , 2011, The Journal of Biological Chemistry.

[56]  X. Qu,et al.  A label-free fluorescent turn-on enzymatic amplification assay for DNA detection using ligand-responsive G-quadruplex formation. , 2011, Chemical communications.

[57]  Chunhui Huang,et al.  A nonemissive iridium(III) complex that specifically lights-up the nuclei of living cells. , 2011, Journal of the American Chemical Society.

[58]  Kim R. Kampen,et al.  Membrane Proteins: The Key Players of a Cancer Cell , 2011, The Journal of Membrane Biology.

[59]  N. Tolwinski,et al.  PTK7/Otk interacts with Wnts and inhibits canonical Wnt signalling , 2011, The EMBO journal.

[60]  F. Puppo,et al.  Protein tyrosine kinase 7 has a conserved role in Wnt/β‐catenin canonical signalling , 2011, EMBO reports.

[61]  Qiang Zhao,et al.  Phosphorescent heavy-metal complexes for bioimaging. , 2011, Chemical Society reviews.

[62]  Xiaogang Qu,et al.  A label-free, quadruplex-based functional molecular beacon (LFG4-MB) for fluorescence turn-on detection of DNA and nuclease. , 2011, Chemistry.

[63]  D. Grimm,et al.  Diagnostic and therapeutic use of membrane proteins in cancer cells. , 2011, Current medicinal chemistry.

[64]  X. Qu,et al.  Silver metallization engineered conformational switch of G-quadruplex for fluorescence turn-on detection of biothiols. , 2012, Chemical communications.

[65]  W. Marsden.  I and J , 2012 .

[66]  J. Mergny,et al.  Tri-G-quadruplex: controlled assembly of a G-quadruplex structure from three G-rich strands. , 2012, Angewandte Chemie.

[67]  X. Qu,et al.  Human telomeric G-quadruplex formation and highly selective fluorescence detection of toxic strontium ions. , 2012, Molecular bioSystems.

[68]  N. Tolwinski,et al.  The many roles of PTK7: a versatile regulator of cell-cell communication. , 2012, Archives of biochemistry and biophysics.

[69]  Kemin Wang,et al.  One-step engineering of silver nanoclusters-aptamer assemblies as luminescent labels to target tumor cells. , 2012, Nanoscale.

[70]  B. Li,et al.  PTK7: a new biomarker for immunophenotypic characterization of maturing T cells and T cell acute lymphoblastic leukemia. , 2012, Leukemia research.

[71]  Wei Feng,et al.  Blue-emissive upconversion nanoparticles for low-power-excited bioimaging in vivo. , 2012, Journal of the American Chemical Society.

[72]  Qian Liu,et al.  A general strategy for biocompatible, high-effective upconversion nanocapsules based on triplet-triplet annihilation. , 2013, Journal of the American Chemical Society.

[73]  W. Tan,et al.  Exploiting the higher specificity of silver amalgamation: selective detection of mercury(II) by forming Ag/Hg amalgam. , 2013, Analytical chemistry.

[74]  Wei Feng,et al.  Luminescent chemodosimeters for bioimaging. , 2013, Chemical reviews.

[75]  Kemin Wang,et al.  Label-free and turn-on aptamer strategy for cancer cells detection based on a DNA-silver nanocluster fluorescence upon recognition-induced hybridization. , 2013, Analytical chemistry.

[76]  Bingling Li,et al.  "Fitting" makes "sensing" simple: label-free detection strategies based on nucleic acid aptamers. , 2013, Accounts of chemical research.

[77]  W. Tan,et al.  Building fluorescent DNA nanodevices on target living cell surfaces. , 2013, Angewandte Chemie.

[78]  V. Filichev,et al.  Molecular engineering of guanine-rich sequences: Z-DNA, DNA triplexes, and G-quadruplexes. , 2013, Chemical Reviews.

[79]  Qian Wang,et al.  Highly sensitive and homogeneous detection of membrane protein on a single living cell by aptamer and nicking enzyme assisted signal amplification based on microfluidic droplets. , 2014, Analytical chemistry.

[80]  Lihua Lu,et al.  Detection of nicking endonuclease activity using a G-quadruplex-selective luminescent switch-on probe , 2014 .

[81]  I. Willner,et al.  From cascaded catalytic nucleic acids to enzyme-DNA nanostructures: controlling reactivity, sensing, logic operations, and assembly of complex structures. , 2014, Chemical reviews.

[82]  Sheng Lin,et al.  Label-free luminescence switch-on detection of hepatitis C virus NS3 helicase activity using a G-quadruplex-selective probe† †Electronic supplementary information (ESI) available: Compound characterisation and supplementary data. See DOI: 10.1039/c4sc03319a Click here for additional data file. , 2014, Chemical science.

[83]  Aaas News,et al.  Book Reviews , 1893, Buffalo Medical and Surgical Journal.