DNA: a model compound for solution studies of macromolecules

Well-defined, monodisperse, homologous series of oligonucleotides and DNA restriction fragments may now be produced and used as models of rigid and semirigid rodlike molecules in solution. Information from optical experiments on these model systems aids in the formulation and testing of theories of macromolecular dynamics in both dilute and concentrated solution.

[1]  R. Pecora,et al.  A dynamic light scattering study of four DNA restriction fragments , 1990 .

[2]  M. Tirado,et al.  Dimensions of short, rodlike macromolecules from translational and rotational diffusion coefficients. Study of the gramicidin dimer , 1984 .

[3]  J. G. Elias,et al.  The dimensions of DNA in solution. , 1981, Journal of molecular biology.

[4]  R. L. Baldwin,et al.  Inhibition of cation‐induced DNA condensation by intercalating dyes , 1983, Biopolymers.

[5]  H. Yamakawa,et al.  Statistical mechanics of helical wormlike chains. I. Differential equations and moments , 1976 .

[6]  José García de la Torre,et al.  Rotational dynamics of rigid, symmetric top macromolecules. Application to circular cylinders , 1980 .

[7]  O. Webster Living Polymerization Methods , 1991, Science.

[8]  S. Diekmann,et al.  Orientation relaxation of DNA restriction fragments and the internal mobility of the double helix. , 1982, Biophysical chemistry.

[9]  M. Szwarc,et al.  POLYMERIZATION INITIATED BY ELECTRON TRANSFER TO MONOMER. A NEW METHOD OF FORMATION OF BLOCK POLYMERS1 , 1956 .

[10]  D. Kondepudi,et al.  Field-induced instabilities in two-component systems: the cell-free glycolytic system. , 1978, Biophysical chemistry.

[11]  B. Zimm,et al.  Theory of DNA condensation: Collapse versus aggregation , 1982, Biopolymers.

[12]  M. Hagenbüchle,et al.  Dynamic light scattering studies on charged rod‐like fd‐virus in dilute aqueous solution , 1990 .

[13]  M. Mandel,et al.  Dynamic light scattering by aqueous solutions of low-molar-mass DNA fragments in the presence of sodium chloride , 1989 .

[14]  R. Lewis,et al.  Transient electric birefringence measurements of the rotational and internal bending modes in monodisperse DNA fragments , 1986 .

[15]  B. Zimm Dynamics of Polymer Molecules in Dilute Solution: Viscoelasticity, Flow Birefringence and Dielectric Loss , 1956 .

[16]  P. Hagerman,et al.  Investigation of the flexibility of DNA using transient electric birefringence , 1981, Biopolymers.

[17]  R. Pecora Spectral Distribution of Light Scattered by Monodisperse Rigid Rods , 1968 .

[18]  K. Schmitz,et al.  Dynamic Light Scattering Studies of Biopolymers: Effects of Charge, Shape, and Flexibility , 1986 .

[19]  T. Yonezawa,et al.  Cationic Polymerization of 1, 2-Dialkoxyethylenes , 1971 .

[20]  W. Urbach,et al.  Mass diffusion measurements in liquid crystals by a novel optical method , 1978 .

[21]  M. Fried,et al.  DNA gelation in concentrated solutions , 1984, Biopolymers.

[22]  Sergio R. Aragon,et al.  Dynamics of wormlike chains , 1985 .

[23]  N. Stellwagen Electric birefringence of restriction enzyme fragments of DNA: Optical factor and electric polarizability as a function of molecular weight , 1981, Biopolymers.

[24]  S. Provencher A constrained regularization method for inverting data represented by linear algebraic or integral equations , 1982 .

[25]  S. Boxer,et al.  Characterization of the overall and internal dynamics of short oligonucleotides by depolarized dynamic light scattering and NMR relaxation measurements. , 1990, Biochemistry.

[26]  R. Pecora,et al.  Spectral Distribution of Light Scattered from Flexible-Coil Macromolecules , 1968 .

[27]  Piazza,et al.  Stretched-exponential relaxation of electric birefringence in polymer solutions. , 1990, Physical review letters.

[28]  M. Mandel,et al.  The ionic strength dependence of the second virial coefficient of low molar mass DNA fragments in aqueous solutions , 1989 .

[29]  Teresa E. Strzelecka,et al.  Solid-state phosphorus-31 NMR studies of DNA liquid crystalline phases. Isotropic to cholesteric transition , 1987 .

[30]  Roger J. Lewis,et al.  Rotational and translational motion of supercoiled plasmids in solution , 1985 .

[31]  R. Lewis,et al.  Brownian dynamics simulations of a three‐subunit and a ten‐subunit worm‐like chain: Comparison of results with trumbell theory and with experimental results from DNA , 1988 .

[32]  José García de la Torre,et al.  Translational friction coefficients of rigid, symmetric top macromolecules. Application to circular cylinders , 1979 .

[33]  Jonathan Widom,et al.  Monomolecular condensation of λ‐DNA induced by cobalt hexammine , 1983 .

[34]  B. Zimm,et al.  Monte Carlo approach to the analysis of the rotational diffusion of wormlike chains , 1981 .

[35]  R. Pecora,et al.  Brownian dynamics simulations of wormlike chains: dynamic light scattering from a 2311 base pair DNA fragment , 1990 .

[36]  T. Härd,et al.  Association of short DNA fragments: Steady state fluorescence polarization study , 1986, Biopolymers.

[37]  Takenao Yoshizaki,et al.  Dynamics of helical worm‐like chains. IV. Dielectric relaxation , 1984 .

[38]  V. Bloomfield,et al.  Ionic strength effects on macroion diffusion and excess light‐scattering intensities of short DNA rods , 1981, Biopolymers.

[39]  R. Pastor,et al.  Frictional models for stochastic simulations of proteins , 1988, Biopolymers.

[40]  J. Hearst,et al.  FRAP and FCS studies of self-diffusion and mutual diffusion in entangled DNA solutions , 1989 .

[41]  J. G. Elias,et al.  Transient electric birefringence study of the persistence length and electrical polarizability of restriction fragments of DNA , 1981 .

[42]  S. Boxer,et al.  Multinuclear NMR studies of DNA hairpins. 1. Structure and dynamics of d(CGCGTTGTTCGCG). , 1989, Biochemistry.

[43]  J. G. Elias,et al.  Transient electric birefringence study of the length and stiffness of short DNA restriction fragments , 1981 .

[44]  Aaas News,et al.  Book Reviews , 1893, Buffalo Medical and Surgical Journal.

[45]  R. Pecora Doppler Shifts in Light Scattering from Pure Liquids and Polymer Solutions , 1964 .

[46]  George D. J. Phillies,et al.  An Introduction to Dynamic Light Scattering by Macromolecules , 1990 .

[47]  B. Zimm,et al.  Light‐scattering study of DNA condensation: Competition between collapse and aggregation , 1982, Biopolymers.

[48]  T. Strzelecka,et al.  Phase transitions of concentrated DNA solutions in low concentrations of 1 : 1 supporting electrolyte , 1990, Biopolymers.

[49]  José García de la Torre,et al.  Comparison of theories for the translational and rotational diffusion coefficients of rod‐like macromolecules. Application to short DNA fragments , 1984 .

[50]  H. Frisch,et al.  Thermodynamics and equilibrium sedimentation analysis of the close approach of DNA molecules and a molecular ordering transition , 1981, Biopolymers.

[51]  B. Zimm,et al.  An elastic hinge model for dynamics of stiff chains. I. Viscoelastic properties , 1984 .

[52]  B. Zimm,et al.  An elastic hinge model for dynamics of stiff chains. II. Transient electro‐optical properties , 1984 .