Neuro-Behcet's Disease Mimicking a Cerebral Tumor

We report a rare case of neuro-Beh et's disease (NBD) presenting as an inflam- matory pseudotumor in the brain. A 52-yr-old woman was evaluated for subacute dizziness and headache. Brain magnetic resonance (MR) imaging showed a right cerebellar mass, which disappeared 2 weeks later. After a year, recurrent muco- cutaneous manifestations of Beh et's disease were observed. Immunosuppres- sant and steroid maintenance treatment were started. She experienced two more neurologic attacks and brain MR imaging revealed an enhancing mass in the right temporal lobe. The second attack showed a good response to steroid pulse ther- apy, but the third attack did not respond to steroid and her neurologic signs sug- gested an impending transtentorial hernia. The right temporal lobectomy was per- formed for the purpose of life-saving. The pathologic finding of the mass was a chronic inflammatory vasculitis, compatible with NBD.

[1]  M. Neudorfer,et al.  Behçet's disease presenting as a cerebral tumour , 2004, Neuroradiology.

[2]  À. Rovira,et al.  Behcet's syndrome masquerading as tumor , 2004, Neuroradiology.

[3]  G. Akman-Demir,et al.  Clinical patterns of neurological involvement in Behçet's disease: evaluation of 200 patients. The Neuro-Behçet Study Group. , 1999, Brain : a journal of neurology.

[4]  O. Çoban,et al.  Masked assessment of MRI findings: is it possible to differentiate neuro-Behçet's disease from other central nervous system , 1999, Neuroradiology.

[5]  Kim Jh,et al.  Neuro-Behcet diseases showing pseudotumoral presentation. , 1998 .

[6]  L. Calabrese,et al.  Neurologic manifestations of systemic vasculitides. , 1994, Seminars in neurology.

[7]  D. Miller,et al.  MAGNETIC-RESONANCE-IMAGING OF THE CENTRAL-NERVOUS-SYSTEM IN BEHCETS-DISEASE , 1993 .

[8]  M. Vidailhet,et al.  MRI in 31 patients with Behçet's disease and neurological involvement: prospective study with clinical correlation. , 1993, Journal of neurology, neurosurgery, and psychiatry.

[9]  J. Degos,et al.  Pseudotumoral neuro-Behçet's disease. , 1993, Surgical neurology.

[10]  Y. Kuroda,et al.  [An immunopathological study during steroid-responsive and steroid-nonresponsive stages on a patient with neuro-Behçet's disease]. , 1993, Rinsho shinkeigaku = Clinical neurology.

[11]  D. Miller,et al.  Magnetic resonance imaging of the central nervous system in Behçet's disease. , 1993, European neurology.

[12]  M. Z. al Kawi,et al.  MRI findings in neuro‐Behcet's disease , 1991, Neurology.

[13]  G. Plant,et al.  Behcet's disease with slowly enlarging midbrain mass on MRI , 1989, Neurology.

[14]  V. Iragui,et al.  Behcet syndrome presenting as cerebrovascular disease. , 1986, Journal of neurology, neurosurgery, and psychiatry.

[15]  K. Tani,et al.  Pathologically defined neuro-, vasculo-, entero-Behçet's disease. , 1985, The Journal of rheumatology.