Altered lipid composition and enzyme activities of plasma membranes from Trypanosoma (Schizotrypanum) cruzi epimastigotes grown in the presence of sterol biosynthesis inhibitors.

[1]  J. Urbina,et al.  Antiproliferative Effects of △24(25) Sterol Methyl Transferase Inhibitors on Trypanosoma (Schizotrypanum) cruzi: In vitro and in vivo Studies , 1996 .

[2]  E. Oldfield,et al.  Molecular order and dynamics of phosphatidylcholine bilayer membranes in the presence of cholesterol, ergosterol and lanosterol: a comparative study using 2H-, 13C- and 31P-NMR spectroscopy. , 1995, Biochimica et biophysica acta.

[3]  J. Urbina,et al.  Modification of the sterol composition of Trypanosoma (Schizotrypanum) cruzi epimastigotes by delta 24(25)-sterol methyl transferase inhibitors and their combinations with ketoconazole. , 1995, Molecular and biochemical parasitology.

[4]  Q. -. Li,et al.  Comparison of the effects of cholesterol and oxysterols on phospholipid bilayer microheterogeneity: a study of fluorescence lifetime distributions. , 1994, Archives of biochemistry and biophysics.

[5]  G. Ourisson,et al.  Interactions of oxysterols with a lipid membrane model : solid-state 2H-NMR studies , 1994 .

[6]  P. Marichal,et al.  Effects of itraconazole on cytochrome P-450-dependent sterol 14 alpha-demethylation and reduction of 3-ketosteroids in Cryptococcus neoformans , 1993, Antimicrobial Agents and Chemotherapy.

[7]  F. Gil,et al.  Inhibition of phosphatidylcholine biosynthesis and cell proliferation in Trypanosoma cruzi by ajoene, an antiplatelet compound isolated from garlic. , 1993, Biochemical pharmacology.

[8]  W. de Souza,et al.  Mevinolin (lovastatin) potentiates the antiproliferative effects of ketoconazole and terbinafine against Trypanosoma (Schizotrypanum) cruzi: in vitro and in vivo studies , 1993, Antimicrobial Agents and Chemotherapy.

[9]  W. D. Nes,et al.  The structural requirements of sterols for membrane function in Saccharomyces cerevisiae. , 1993, Archives of biochemistry and biophysics.

[10]  E. Mercer Inhibitors of sterol biosynthesis and their applications. , 1993, Progress in lipid research.

[11]  N. Georgopapadakou,et al.  Emerging Targets in Antibacterial and Antifungal Chemotherapy , 2012, Springer US.

[12]  A. Endo,et al.  The discovery and development of HMG-CoA reductase inhibitors. , 1992, Journal of lipid research.

[13]  N. Ryder,et al.  Biochemical Aspects of Ergosterol Biosynthesis Inhibition , 1992 .

[14]  N. Ryder,et al.  Allylamine antifungal drugs. , 1992, Current topics in medical mycology.

[15]  S. Schreier,et al.  Cholesterol modulation of lipid-protein interactions in liver microsomal membrane: a spin label study. , 1991, Biochemistry.

[16]  S. Kelly,et al.  Molecular genetic studies on the mode of action of azole antifungal agents. , 1991, Biochemical Society transactions.

[17]  W. de Souza,et al.  Ultrastructural alterations induced by ICI 195,739, a bis-triazole derivative with strong antiproliferative action against Trypanosoma (Schizotrypanum) cruzi , 1991, Antimicrobial Agents and Chemotherapy.

[18]  J. Urbina,et al.  Antiproliferative effects and mechanism of action of ICI 195,739, a novel bis-triazole derivative, on epimastigotes and amastigotes of Trypanosoma (Schizotrypanum) cruzi , 1991, Antimicrobial Agents and Chemotherapy.

[19]  W. de Souza,et al.  Ultrastructural alterations induced by two ergosterol biosynthesis inhibitors, ketoconazole and terbinafine, on epimastigotes and amastigotes of Trypanosoma (Schizotrypanum) cruzi , 1990, Antimicrobial Agents and Chemotherapy.

[20]  M. Zundel,et al.  Sterol effects on phospholipid biosynthesis in the yeast strain GL7. , 1990, Journal of lipid research.

[21]  N. Ryder Squalene Epoxidase — Enzymology and Inhibition , 1990 .

[22]  H. Bossche Importance and Role of Sterols in Fungal Membranes , 1990 .

[23]  D. Beach,et al.  The activity of ketoconazole and other azoles against Trypanosoma cruzi: biochemistry and chemotherapeutic action in vitro. , 1989, Molecular and biochemical parasitology.

[24]  H. Geerts,et al.  Mode of Action Studies: Basis for the Search of New Antifungal Drugs , 1988, Annals of the New York Academy of Sciences.

[25]  D. Zilberstein,et al.  Identification of a surface membrane proton-translocating ATPase in promastigotes of the parasitic protozoan Leishmania donovani. , 1988, The Biochemical journal.

[26]  J. Urbina,et al.  Antiproliferative synergism of the allylamine SF 86-327 and ketoconazole on epimastigotes and amastigotes of Trypanosoma (Schizotrypanum) cruzi , 1988, Antimicrobial Agents and Chemotherapy.

[27]  L. Avilan,et al.  Alteration of lipid order profile and permeability of plasma membranes from Trypanosoma cruzi epimastigotes grown in the presence of ketoconazole. , 1988, Molecular and biochemical parasitology.

[28]  N. Ryder Mode of action of allylamines , 1988 .

[29]  D. Berg,et al.  Sterol biosynthesis inhibitors. Pharmaceutical and agrochemical aspects. , 1988 .

[30]  H. Lyr Modern Selective Fungicides , 1987 .

[31]  N. Georgopapadakou,et al.  Effect of antifungal agents on lipid biosynthesis and membrane integrity in Candida albicans , 1987, Antimicrobial Agents and Chemotherapy.

[32]  H. Lyr,et al.  Modern selective fungicides : properties, applications, mechanisms of action , 1987 .

[33]  E. Parish,et al.  Control of fungal sterol C-24 transalkylation: importance to developmental regulation. , 1986, Biochemical and biophysical research communications.

[34]  P. Cullis,et al.  Lipid polymorphism and the roles of lipids in membranes. , 1986, Chemistry and physics of lipids.

[35]  L. W. Parks,et al.  Multiple functions for sterols in Saccharomyces cerevisiae. , 1985, Biochimica et biophysica acta.

[36]  L. W. Parks,et al.  Influence of sterol structure on yeast plasma membrane properties. , 1985, Biochimica et biophysica acta.

[37]  S. Gruner,et al.  Lipid polymorphism: the molecular basis of nonbilayer phases. , 1985, Annual review of biophysics and biophysical chemistry.

[38]  H. van den Bossche,et al.  Hypothesis on the molecular basis of the antifungal activity of N-substituted imidazoles and triazoles. , 1983, Biochemical Society transactions.

[39]  B. de Kruijff,et al.  Correlation between molecular shape and hexagonal HII phase promoting ability of sterols , 1982, FEBS letters.

[40]  K. Bloch,et al.  Sterol structure and membrane function. , 1981, Current topics in cellular regulation.

[41]  C. F. Fox,et al.  Biochemistry of cell walls and membranes , 1975 .

[42]  M. B. de Sastre,et al.  Demonstration of a Mg2+‐activated adenosine triphosphatase in Trypanosoma cruzi , 1973, FEBS letters.

[43]  Sonck Ce Chemotherapy of fungal infections , 1970 .

[44]  M. Cuzner,et al.  Quantitative thin layer chromatography of lipids. , 1967, Journal of chromatography.

[45]  B. Ames,et al.  The role of polyamines in the neutralization of bacteriophage deoxyribonucleic acid. , 1960, The Journal of biological chemistry.