Loss of breast epithelial marker hCLCA2 promotes epithelial to mesenchymal transition and indicates higher risk of metastasis
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Yang Yu | Miao Sun | Sendurai A Mani | R. Elble | Krishna Rao | Miao Sun | Janel R. McLean | Vijay Walia | Yang Yu | Vijay Walia | Deshou Cao | Brett G. Hollier | Jiming Cheng | Sendurai A. Mani | Krishna Rao | Louis Premkumar | Randolph Elble | B. Hollier | L. Premkumar | Jiming Cheng | D. Cao
[1] C. V. Jongeneel,et al. Establishment of the epithelial-specific transcriptome of normal and malignant human breast cells based on MPSS and array expression data , 2006, Breast Cancer Research.
[2] R. Elble,et al. Enrichment for breast cancer cells with stem/progenitor properties by differential adhesion. , 2010, Stem cells and development.
[3] J. McDougall,et al. Production of spindle cell carcinoma by transduction of H-Ras 61L into immortalized human mammary epithelial cells. , 2003, Cancer letters.
[4] Jason I. Herschkowitz,et al. Phenotypic and molecular characterization of the claudin-low intrinsic subtype of breast cancer , 2010, Breast Cancer Research.
[5] R. Weinberg,et al. Transitions between epithelial and mesenchymal states: acquisition of malignant and stem cell traits , 2009, Nature Reviews Cancer.
[6] H. Sontheimer. An Unexpected Role for Ion Channels in Brain Tumor Metastasis , 2008, Experimental biology and medicine.
[7] F Gambale,et al. Inhibition of Bax channel-forming activity by Bcl-2. , 1997, Science.
[8] F. Bertucci,et al. Gene expression profiling of breast cell lines identifies potential new basal markers , 2006, Oncogene.
[9] J. Foekens,et al. Gene-expression profiles to predict distant metastasis of lymph-node-negative primary breast cancer , 2005, The Lancet.
[10] R. Shirkoohi,et al. siRNA gelsolin knockdown induces epithelial‐mesenchymal transition with a cadherin switch in human mammary epithelial cells , 2006, International journal of cancer.
[11] W. Hahn,et al. Human breast cancer cells generated by oncogenic transformation of primary mammary epithelial cells. , 2001, Genes & development.
[12] C Caldas,et al. Somatic mutations in the p53 gene and prognosis in breast cancer: a meta-analysis , 1999, British Journal of Cancer.
[13] J. Ingle,et al. Abrogation of p53 function leads to metastatic transcriptome networks that typify tumor progression in human breast cancer xenografts. , 2010, International journal of oncology.
[14] T. Machen,et al. Bicarbonate conductance and pH regulatory capability of cystic fibrosis transmembrane conductance regulator. , 1994, Proceedings of the National Academy of Sciences of the United States of America.
[15] J. Pouysségur,et al. Hypoxia signalling in cancer and approaches to enforce tumour regression , 2006, Nature.
[16] W. Hahn,et al. Identification of PP2A complexes and pathways involved in cell transformation. , 2010, Cancer research.
[17] L. Counillon,et al. CFTR modulates programmed cell death by decreasing intracellular pH in Chinese hamster lung fibroblasts. , 2001, American journal of physiology. Cell physiology.
[18] R. Weinberg,et al. Enrichment of a population of mammary gland cells that form mammospheres and have in vivo repopulating activity. , 2007, Cancer research.
[19] M. Sartor,et al. In vitro multipotent differentiation and barrier function of a human mammary epithelium , 2009, Cell and Tissue Research.
[20] V. Rotter,et al. Mutant p53R175H upregulates Twist1 expression and promotes epithelial–mesenchymal transition in immortalized prostate cells , 2011, Cell Death and Differentiation.
[21] P. Porter,et al. Cytogenetic characterization and H-ras associated transformation of immortalized human mammary epithelial cells , 2006, Cancer Cell International.
[22] Kakajan Komurov,et al. Core epithelial-to-mesenchymal transition interactome gene-expression signature is associated with claudin-low and metaplastic breast cancer subtypes , 2010, Proceedings of the National Academy of Sciences.
[23] L. Fliegel,et al. Mitogen-activated Protein Kinase-dependent Activation of the Na+/H+ Exchanger Is Mediated through Phosphorylation of Amino Acids Ser770 and Ser771* , 2007, Journal of Biological Chemistry.
[24] Jason I. Herschkowitz,et al. Rb deletion in mouse mammary progenitors induces luminal-B or basal-like/EMT tumor subtypes depending on p53 status. , 2010, The Journal of clinical investigation.
[25] A. Gruber,et al. The Putative Chloride Channel hCLCA2 Has a Single C-terminal Transmembrane Segment* , 2006, Journal of Biological Chemistry.
[26] M. Tang,et al. KCl cotransporter-3 down-regulates E-cadherin/beta-catenin complex to promote epithelial-mesenchymal transition. , 2007, Cancer research.
[27] K. Kunzelmann. Ion Channels and Cancer , 2005, The Journal of Membrane Biology.
[28] Benjamin M. Bolstad,et al. affy - analysis of Affymetrix GeneChip data at the probe level , 2004, Bioinform..
[29] E. Lander,et al. Loss of E-cadherin promotes metastasis via multiple downstream transcriptional pathways. , 2008, Cancer research.
[30] A. Eastman,et al. Endonuclease activation during apoptosis: the role of cytosolic Ca2+ and pH. , 1992, Biochemical and biophysical research communications.
[31] M. Hamann,et al. Human ClCa1 modulates anionic conduction of calcium-dependent chloride currents , 2009, The Journal of physiology.
[32] J. Thiery,et al. Complex networks orchestrate epithelial–mesenchymal transitions , 2006, Nature Reviews Molecular Cell Biology.
[33] Sumit Kumar,et al. hCLCA2 Is a p53-Inducible Inhibitor of Breast Cancer Cell Proliferation. , 2009, Cancer research.
[34] S. Lowe,et al. Oncogenic ras activates the ARF-p53 pathway to suppress epithelial cell transformation , 2001, Proceedings of the National Academy of Sciences of the United States of America.
[35] Nicholas J. Wang,et al. Characterization of a naturally occurring breast cancer subset enriched in epithelial-to-mesenchymal transition and stem cell characteristics. , 2009, Cancer research.
[36] K. Polyak,et al. Psoriasin expression in mammary epithelial cells in vitro and in vivo. , 2002, Cancer research.
[37] A. Gruber,et al. Tumorigenicity of human breast cancer is associated with loss of the Ca2+-activated chloride channel CLCA2. , 1999, Cancer research.
[38] John P. Moore,et al. A common sequence of calcium and pH signals in the mitogenic stimulation of eukaryotic cells , 1985, Nature.
[39] M. Collins,et al. Intracellular acidification induces apoptosis by stimulating ICE-like protease activity. , 1997, Journal of cell science.
[40] R. Tsien,et al. Na+/H+ exchange and cytoplasmic pH in the action of growth factors in human fibroblasts , 1983, Nature.
[41] C. Heldin,et al. Signaling networks guiding epithelial–mesenchymal transitions during embryogenesis and cancer progression , 2007, Cancer science.
[42] J. Thiery. Epithelial–mesenchymal transitions in tumour progression , 2002, Nature Reviews Cancer.
[43] R. Serrano,et al. Increased pH and tumorigenicity of fibroblasts expressing a yeast proton pump , 1988, Nature.
[44] T. Crook,et al. The p53 pathway in breast cancer , 2002, Breast Cancer Research.
[45] S. Eschrich,et al. The gene expression profiles of primary and metastatic melanoma yields a transition point of tumor progression and metastasis , 2008, BMC Medical Genomics.
[46] J. Locker,et al. Loss of retinal cadherin facilitates mammary tumor progression and metastasis. , 2009, Cancer research.
[47] G. Dontu,et al. In vitro propagation and transcriptional profiling of human mammary stem/progenitor cells. , 2003, Genes & development.
[48] E. Fearon,et al. The SLUG zinc-finger protein represses E-cadherin in breast cancer. , 2002, Cancer research.
[49] K. Sossey-Alaoui,et al. CLCA2 tumour suppressor gene in 1p31 is epigenetically regulated in breast cancer , 2004, Oncogene.
[50] H. Ishwaran,et al. Lung metastasis genes couple breast tumor size and metastatic spread , 2007, Proceedings of the National Academy of Sciences.
[51] Gema Moreno-Bueno,et al. Epithelial-mesenchymal transition in breast cancer relates to the basal-like phenotype. , 2008, Cancer research.
[52] Krishna Rao,et al. Loss of RAB25 expression in breast cancer , 2006, International journal of cancer.
[53] Wenjun Guo,et al. The Epithelial-Mesenchymal Transition Generates Cells with Properties of Stem Cells , 2008, Cell.
[54] Jeffrey M. Rosen,et al. Epithelial-Mesenchymal Transition (EMT) in Tumor-Initiating Cells and Its Clinical Implications in Breast Cancer , 2010, Journal of Mammary Gland Biology and Neoplasia.
[55] Francisco Portillo,et al. The transcription factor Snail controls epithelial–mesenchymal transitions by repressing E-cadherin expression , 2000, Nature Cell Biology.
[56] Archana Dhasarathy,et al. The Transcription Factor Snail Mediates Epithelial to Mesenchymal Transitions by Repression of Estrogen Receptor - , 2007 .