Beta-Adrenergic Blocking Drugs in Anaesthesia

Beta-adrenergic blocking drugs have progressively become more widely used since their introduction in the mid-1960's. Their importance to anaesthetists lies in their ability to modify the normal responses to anaesthetic agents and to the stresses encountered during surgery. Anaesthetists are concerned with betablockers in two basic situations. The first situation occurs when a decision has to be made preoperatively whether or not to continue medication during anaesthesia in a patient already taking one of these drugs. The second is during anaesthesia when the initiation of beta-adrenergic blockade may be desirable. A knowledge of the basic pharmacology of these drugs and their interaction with anaesthetic agents will resolve many problems which may arise in a clinical situation.

[1]  D. Scott,et al.  Cardiovascular effects of intravenous lignocaine during nitrous oxide-halothane anaesthesia. , 1971, British Journal of Anaesthesia.

[2]  D. Scott,et al.  Haemodynamic effects of beta-receptor blocking drugs during nitrous oxide-halothane anaesthesia. , 1971, British journal of anaesthesia.

[3]  B. Joffe,et al.  The use and abuse of beta-adrenergic blockade in the surgery of hyperthyroidism. , 1970, South African medical journal = Suid-Afrikaanse tydskrif vir geneeskunde.

[4]  J. Norman,et al.  The effect of cardiac sympathetic blockade on the relationship between cardiac output and carbon dioxide tension in the anaesthetized dog. , 1970, British journal of anaesthesia.

[5]  K. Weis,et al.  On the cardiovascular effect of propranolol during halothane anaesthesia in normovolaemic and hypovolaemic dogs. , 1970, British journal of anaesthesia.

[6]  P. Sharma,et al.  Selective adrenergic beta-receptor blockade in the prevention of adrenaline-evoked ventricular arrhythmias in dogs anaesthetized with halothane in oxygen. , 1969, British journal of anaesthesia.

[7]  J. Fitzgerald.  Perspectives in adrenergic beta‐receptor blockade , 1969, Clinical pharmacology and therapeutics.

[8]  J. W. Cox,et al.  Effects of Beta‐Adrenergic Blockade (Propranolol) on Left Ventricular Hemodynamics and the Electrocardiogram During Exercise‐Induced Angina Pectoris , 1968, Circulation.

[9]  R G Shanks,et al.  Selective blockade of adrenoceptive beta receptors in the heart. , 1968, British journal of pharmacology and chemotherapy.

[10]  H. L. Price,et al.  Control of the Splanchnic Circulation in Man: ROLE OF BETA‐ADRENERGIC RECEPTORS , 1967, Circulation research.

[11]  K. Engelman,et al.  Anesthetic management of pheochromocytoma employing halothane and beta adrenergic blockade. A report of fourteen cases. , 1967, Anesthesiology.

[12]  P. B. Hewitt,et al.  Propranolol in hypotensive anaesthesia , 1967, Anaesthesia.

[13]  B. Prichard,et al.  Use of propranolol in conjunction with alpha receptor blocking drugs in pheochromocytoma. , 1966, The American journal of cardiology.