Oxidized Cellulose for Epithelialization of Neovagina in Vaginal Agenesis

Abstract Objective: The study objective was to evaluate use of oxidized regenerated cellulose (Surgicel®) for epithelialization of neovagina in vaginal agenesis. Design: A prospective, longitudinal study (Canadian Task Force classification II-2) was conducted at a tertiary care center. Method: Ten (10) women (ages: 17–25 years) with vaginal agenesis, undergoing surgical construction of vagina over a period of 2 years, were included in the study. The surgical technique involved creation of a neovagina by modified Sheares technique, followed by use of a foam mold covered with a condom and further wrapped in oxidized cellulose to aid epithelialization. The main outcome measures evaluated were effectiveness and complications (if any) with the use of oxidized cellulose for epithelialization of neovagina. Results: There were no intraoperative complications. Adequate vaginal length (7–10 cm) was achieved in all cases on foam mold removal. On follow-up at 6 months, all vaginas were well epithelialized. One (1) pa...