Neuronal carbonic anhydrase VII provides GABAergic excitatory drive to exacerbate febrile seizures

[1]  K. Kaila,et al.  Carbonic anhydrases and brain pH in the control of neuronal excitability. , 2014, Sub-cellular biochemistry.

[2]  W. Sly,et al.  NMDA Receptor-Dependent Afterdepolarizations Are Curtailed by Carbonic Anhydrase 14: Regulation of a Short-Term Postsynaptic Potentiation , 2012, The Journal of Neuroscience.

[3]  Hye-Young Heo,et al.  Detecting activity-evoked pH changes in human brain , 2012, Proceedings of the National Academy of Sciences.

[4]  R. McKenna,et al.  Lactate flux in astrocytes is enhanced by a non‐catalytic action of carbonic anhydrase II , 2012, The Journal of physiology.

[5]  C. Supuran,et al.  Carbonic anhydrase VII is S-glutathionylated without loss of catalytic activity and affinity for sulfonamide inhibitors. , 2012, Bioorganic & medicinal chemistry letters.

[6]  K. Kaila,et al.  Respiratory alkalosis in children with febrile seizures , 2011, Epilepsia.

[7]  J. Kleinman,et al.  Spatiotemporal transcriptome of the human brain , 2011, Nature.

[8]  A. Roepstorff,et al.  Enhancing effects of acetazolamide on neuronal activity correlate with enhanced visual processing ability in humans , 2011, Neuropharmacology.

[9]  C. Bruehl,et al.  Synaptic Glutamate Release Is Modulated by the Na+-Driven Cl−/HCO3− Exchanger Slc4a8 , 2011, The Journal of Neuroscience.

[10]  Sampsa Vanhatalo,et al.  Five percent CO2 is a potent, fast‐acting inhalation anticonvulsant , 2011, Epilepsia.

[11]  C. Reid,et al.  Temperature elevation increases GABAA‐mediated cortical inhibition in a mouse model of genetic epilepsy , 2011, Epilepsia.

[12]  K. Kaila,et al.  Spontaneous Network Events Driven by Depolarizing GABA Action in Neonatal Hippocampal Slices are Not Attributable to Deficient Mitochondrial Energy Metabolism , 2010, The Journal of Neuroscience.

[13]  R. Dingledine,et al.  Glutamate Receptor Ion Channels: Structure, Regulation, and Function , 2010, Pharmacological Reviews.

[14]  Holger Lerche,et al.  Axon initial segment dysfunction in a mouse model of genetic epilepsy with febrile seizures plus. , 2010, The Journal of clinical investigation.

[15]  W. Sly,et al.  Analysis of a shortened form of human carbonic anhydrase VII expressed in vitro compared to the full-length enzyme. , 2010, Biochimie.

[16]  Tero Viitanen,et al.  The K+–Cl− cotransporter KCC2 promotes GABAergic excitation in the mature rat hippocampus , 2010, The Journal of physiology.

[17]  Péter Enyedi,et al.  Molecular Background of Leak K (cid:1) Currents: Two-Pore Domain Potassium Channels , 2010 .

[18]  W. Boron Evaluating the role of carbonic anhydrases in the transport of HCO3--related species. , 2010, Biochimica et biophysica acta.

[19]  Sergio Grinstein,et al.  Sensors and regulators of intracellular pH , 2010, Nature Reviews Molecular Cell Biology.

[20]  K. Kaila,et al.  Neurobiological and physiological mechanisms of fever-related epileptiform syndromes , 2009, Brain and Development.

[21]  B. Spruijt,et al.  Characterization of febrile seizures and febrile seizure susceptibility in mouse inbred strains , 2008, Genes, brain, and behavior.

[22]  K. Kaila,et al.  Pronounced increase in breathing rate in the “hair dryer model” of experimental febrile seizures , 2008, Epilepsia.

[23]  C. Supuran,et al.  Investigations of the esterase, phosphatase, and sulfatase activities of the cytosolic mammalian carbonic anhydrase isoforms I, II, and XIII with 4-nitrophenyl esters as substrates. , 2008, Bioorganic & medicinal chemistry letters.

[24]  Claudiu T. Supuran,et al.  Carbonic anhydrases: novel therapeutic applications for inhibitors and activators , 2008, Nature Reviews Drug Discovery.

[25]  Juha Voipio,et al.  Mice with targeted Slc4a10 gene disruption have small brain ventricles and show reduced neuronal excitability , 2008, Proceedings of the National Academy of Sciences.

[26]  Lars Fugger,et al.  Control of hypothalamic orexin neurons by acid and CO2 , 2007, Proceedings of the National Academy of Sciences.

[27]  J. Deitmer,et al.  Carbonic anhydrase II increases the activity of the human electrogenic Na+/HCO3- cotransporter. , 2007, The Journal of biological chemistry.

[28]  C. Supuran,et al.  Carbonic anhydrase inhibitors as anticonvulsant agents. , 2007, Current topics in medicinal chemistry.

[29]  Tomoki Fukai,et al.  Distinct types of ionic modulation of GABA actions in pyramidal cells and interneurons during electrical induction of hippocampal seizure‐like network activity , 2007, The European journal of neuroscience.

[30]  Mark Farrant,et al.  The cellular, molecular and ionic basis of GABA(A) receptor signalling. , 2007, Progress in brain research.

[31]  T. Baram,et al.  CHAPTER 26 – Complex Febrile Seizures—An Experimental Model in Immature Rodents , 2006 .

[32]  K. Mackie,et al.  Experimental febrile seizures are precipitated by a hyperthermia-induced respiratory alkalosis , 2006, Nature Medicine.

[33]  T. Seidenbecher,et al.  Mice with a Targeted Disruption of the Cl−/HCO3− Exchanger AE3 Display a Reduced Seizure Threshold , 2006, Molecular and Cellular Biology.

[34]  Alastair M. Hosie,et al.  Proton modulation of recombinant GABAA receptors: influence of GABA concentration and the β subunit TM2–TM3 domain , 2005, The Journal of physiology.

[35]  T. Baram,et al.  Interleukin‐1β contributes to the generation of experimental febrile seizures , 2005, Annals of neurology.

[36]  I. Silver,et al.  Energy metabolism in mammalian brain during development , 2004, Progress in Neurobiology.

[37]  J. Palva,et al.  Carbonic Anhydrase Isoform VII Acts as a Molecular Switch in the Development of Synchronous Gamma-Frequency Firing of Hippocampal CA1 Pyramidal Cells , 2004, The Journal of Neuroscience.

[38]  U. Heinemann,et al.  Lowering of extracellular pH suppresses low-Mg2+-induces seizures in combined entorhinal cortex-hippocampal slices , 1994, Experimental Brain Research.

[39]  J. Voipio,et al.  Interstitial PCO2 and pH in rat hippocampal slices measured by means of a novel fast CO2/H+-sensitive microelectrode based on a PVC-gelled membrane , 1993, Pflügers Archiv.

[40]  C. Pfeffer,et al.  Loss of K‐Cl co‐transporter KCC3 causes deafness, neurodegeneration and reduced seizure threshold , 2003, The EMBO journal.

[41]  M. Chesler Regulation and modulation of pH in the brain. , 2003, Physiological reviews.

[42]  G. Richerson,et al.  Quantification of the response of rat medullary raphe neurones to independent changes in pHo and PCO2 , 2002, The Journal of physiology.

[43]  C. Stafstrom The Incidence and Prevalence of Febrile Seizures , 2002 .

[44]  R. Appleton,et al.  Drug management for acute tonic-clonic convulsions including convulsive status epilepticus in children. , 2002, The Cochrane database of systematic reviews.

[45]  R Ottman,et al.  Identification of epilepsy genes in human and mouse. , 2001, Annual review of genetics.

[46]  Alun D. Hughes,et al.  In vivo evidence for KCa channel opening properties of acetazolamide in the human vasculature , 2001, British journal of pharmacology.

[47]  I. Soltesz,et al.  Prolonged febrile seizures in the immature rat model enhance hippocampal excitability long term , 2000, Annals of neurology.

[48]  G. Gros,et al.  Carbon dioxide transport and carbonic anhydrase in blood and muscle. , 2000, Physiological reviews.

[49]  H. Pape,et al.  Modulation of the hyperpolarization‐activated cation current of rat thalamic relay neurones by intracellular pH , 1999, The Journal of physiology.

[50]  I. Choonara,et al.  Respiratory depression in children receiving diazepam for acute seizures: a prospective study , 1999, Developmental medicine and child neurology.

[51]  D. Silverman,et al.  The catalytic properties of murine carbonic anhydrase VII. , 1998, Biochemistry.

[52]  P. Lehenkari,et al.  Carbonic anhydrase II plays a major role in osteoclast differentiation and bone resorption by effecting the steady state intracellular pH and Ca2+. , 1998, Experimental cell research.

[53]  R. Tasker Emergency treatment of acute seizures and status epilepticus , 1998, Archives of disease in childhood.

[54]  Bruce R. Ransom,et al.  pH and brain function , 1998 .

[55]  J. Voipio,et al.  Long-Lasting GABA-Mediated Depolarization Evoked by High-Frequency Stimulation in Pyramidal Neurons of Rat Hippocampal Slice Is Attributable to a Network-Driven, Bicarbonate-Dependent K+ Transient , 1997, The Journal of Neuroscience.

[56]  B. Birnir,et al.  Hippocampal GABAAchannel conductance increased by diazepam , 1997, Nature.

[57]  D. Silverman,et al.  Catalytic Properties of Murine Carbonic Anhydrase IV* , 1997, The Journal of Biological Chemistry.

[58]  K. Ballanyi,et al.  GABA- and glycine-mediated fall of intracellular pH in rat medullary neurons in situ. , 1997, Journal of neurophysiology.

[59]  M. Lazdunski,et al.  A proton-gated cation channel involved in acid-sensing , 1997, Nature.

[60]  K. Kaila,et al.  Proton Modulation of Functionally Distinct GABAA Receptors in Acutely Isolated Pyramidal Neurons of Rat Hippocampus , 1996, Neuropharmacology.

[61]  Anne T. Berg,et al.  Complex Febrile Seizures , 1996, Epilepsia.

[62]  K. Staley,et al.  Ionic mechanisms of neuronal excitation by inhibitory GABAA receptors , 1995, Science.

[63]  T. Gloveli,et al.  Properties of low Mg2+ induced epileptiform activity in rat hippocampal and entorhinal cortex slices during adolescence. , 1995, Brain research. Developmental brain research.

[64]  Peter H. Barry,et al.  JPCalc, a software package for calculating liquid junction potential corrections in patch-clamp, intracellular, epithelial and bilayer measurements and for correcting junction potential measurements , 1994, Journal of Neuroscience Methods.

[65]  Kl Smith,et al.  Localized excitatory synaptic interactions mediate the sustained depolarization of electrographic seizures in developing hippocampus , 1993, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[66]  J. Voipio,et al.  Intracellular carbonic anhydrase activity and its role in GABA-induced acidosis in isolated rat hippocampal pyramidal neurones. , 1993, Acta physiologica Scandinavica.

[67]  S. Venkataraman,et al.  Diazepam and intubation in emergency treatment of seizures in children. , 1991, Annals of emergency medicine.

[68]  J. Voipio,et al.  Effect of gamma-aminobutyric acid on intracellular pH in the crayfish stretch-receptor neurone. , 1991, The Journal of experimental biology.

[69]  T J Sejnowski,et al.  When is an inhibitory synapse effective? , 1990, Proceedings of the National Academy of Sciences of the United States of America.

[70]  J. Voipio,et al.  Mechanism of action of GABA on intracellular pH and on surface pH in crayfish muscle fibres. , 1990, The Journal of physiology.

[71]  F. Miralles,et al.  Effects of diltiazem on hyperthermia induced seizures in the rat pup. , 1990, General pharmacology.

[72]  J. Voipio,et al.  Influence of GABA‐gated bicarbonate conductance on potential, current and intracellular chloride in crayfish muscle fibres. , 1989, The Journal of physiology.

[73]  R. Erickson,et al.  N-ethyl-N-nitrosourea-induced null mutation at the mouse Car-2 locus: an animal model for human carbonic anhydrase II deficiency syndrome. , 1988, Proceedings of the National Academy of Sciences of the United States of America.

[74]  J. Voipio,et al.  Postsynaptic fall in intracellular pH induced by GABA-activated bicarbonate conductance , 1987, Nature.

[75]  B. Hille,et al.  Ionic channels of excitable membranes , 2001 .

[76]  D. Hirtz,et al.  The natural history of febrile seizures. , 1983, Annual review of medicine.

[77]  R. Nicoll,et al.  Pharmacological evidence for two kinds of GABA receptors on rat hippocampal pyramidal cells studied in vitro , 1982, The Journal of physiology.

[78]  D C Spray,et al.  Gap junctional conductance is a simple and sensitive function of intracellular pH. , 1981, Science.

[79]  O. K. Langley,et al.  Immunochemical and immunohistochemical study of carbonic anhydrase II in adult rat cerebellum: A marker for oligodendrocytes , 1980, Neuroscience.

[80]  A. Savitzky,et al.  Smoothing and Differentiation of Data by Simplified Least Squares Procedures. , 1964 .