SARS-CoV-2 Infection in a 2-Week-Old Male With Neutropenia

The novel coronavirus, SARS-CoV-2, has caused a global outbreak of coronavirus disease 2019 (COVID19), which began in Wuhan, Hubei Province, China, in December 2019, and it has rapidly spread to involve 170 countries and regions with 304 528 confirmed cases and 12 973 deaths as of March 21, 2020.1 The spectrum of clinical presentation is varied and nonspecific in adults ranging from mild flu-like illness to florid respiratory failure including acute respiratory distress syndrome.2 Recent data out of China have evaluated the epidemiology of children with COVID-19 and found that children of all ages are affected by the virus and tend to have a milder course of disease compared with adults, though there remains subpopulations of pediatric patients at higher risk for significant disease.2-4 Recognition of disease in this patient population remains critical in both management of disease and for quarantine to limit further transmission. This case report focuses on a 2-week-old male infant who presented to the pediatric emergency department with fever and fussiness. Globally, China has published 2 case reports of neonatal COVID-19 infection, and to the best of our knowledge, there has been no published case reports in the United States of COVID-19 in a patient as young as 2 weeks.5