Brain tumor detection and localization in magnetic resonance imaging

A tumor also known as neoplasm is a growth in the abnormal tissue which can be differentiated from the surrounding tissue by its structure. A tumor may lead to cancer, which is a major leading cause of death and responsible for around 13% of all deaths world-wide. Cancer incidence rate is growing at an alarming rate in the world. Great knowledge and experience on radiology are required for accurate tumor detection in medical imaging. Automation of tumor detection is required because there might be a shortage of skilled radiologists at a time of great need. We propose an automatic brain tumor detection and localization framework that can detect and localize brain tumor in magnetic resonance imaging. The proposed brain tumor detection and localization framework comprises five steps: image acquisition, pre-processing, edge detection, modified histogram clustering and morphological operations. After morphological operations, tumors appear as pure white color on pure black backgrounds. We used 50 neuroimages to optimize our system and 100 out-of-sample neuroimages to test our system. The proposed tumor detection and localization system was found to be able to accurately detect and localize brain tumor in magnetic resonance imaging. The preliminary results demonstrate how a simple machine learning classifier with a set of simple image-based features can result in high classification accuracy. The preliminary results also demonstrate the efficacy and efficiency of our five-step brain tumor detection and localization approach and motivate us to extend this framework to detect and localize a variety of other types of tumors in other types of medical imagery.

[1]  Ronald M. Summers,et al.  Automatic detection of endobronchial lesions using virtual bronchoscopy: comparison of two methods , 1998, Medical Imaging.

[2]  J. Barnholtz-Sloan,et al.  CBTRUS statistical report: primary brain and central nervous system tumors diagnosed in the United States in 2007-2011. , 2012, Neuro-oncology.

[3]  Michael F. McNitt-Gray,et al.  Application of image analysis techniques to distinguish benign from malignant solitary pulmonary nodules imaged on CT , 1998, Medical Imaging.

[4]  T. Logeswari,et al.  An improved implementation of brain tumor detection using segmentation based on soft computing , 2010 .

[5]  P Croisille,et al.  Pulmonary nodules: improved detection with vascular segmentation and extraction with spiral CT. Work in progress. , 1995, Radiology.

[6]  Dina M. Aboul Dahab,et al.  Automated Brain Tumor Detection and Identification Using Image Processing and Probabilistic Neural Network Techniques , 2012 .

[7]  Noboru Niki,et al.  Classification of pulmonary nodules in thin-section CT images based on shape characterization , 1997, Proceedings of International Conference on Image Processing.

[8]  Ardeshir Goshtasby,et al.  On the Canny edge detector , 2001, Pattern Recognit..

[9]  Robin N. Strickland Image-Processing Techniques for Tumor Detection , 2007 .

[10]  Noboru Niki,et al.  Computer aided diagnosis system for lung cancer based on helical CT images , 1997, Medical Imaging.

[11]  Jin Akiyama,et al.  Computational Geometry, Graphs and Applications , 2011, Lecture Notes in Computer Science.

[12]  Tinku Acharya,et al.  Image Processing: Principles and Applications , 2005, J. Electronic Imaging.

[13]  Zaw Zaw Htike,et al.  Classification of Eukaryotic Splice-junction Genetic Sequences Using Averaged One-dependence Estimators with Subsumption Resolution , 2013 .

[14]  Shoon Lei Win,et al.  Recognition of Promoters in DNA Sequences Using Weightily Averaged One-dependence Estimators , 2013 .

[15]  D. Cavouras,et al.  Image analysis methods for solitary pulmonary nodule characterization by computed tomography. , 1992, European journal of radiology.

[16]  Anam Mustaqeem,et al.  An Efficient Brain Tumor Detection Algorithm Using Watershed & Thresholding Based Segmentation , 2012 .

[17]  Mark Beale,et al.  Neural Network Toolbox™ User's Guide , 2015 .

[18]  C. Kruchko,et al.  CBTRUS statistical report: primary brain and central nervous system tumors diagnosed in the United States in 2005-2009. , 2012, Neuro-oncology.

[19]  Noboru Niki,et al.  Three-dimensional analysis of lung areas using thin slice CT images , 1996, Medical Imaging.

[20]  F. Frances Yao,et al.  Computational Geometry , 1991, Handbook of Theoretical Computer Science, Volume A: Algorithms and Complexity.

[21]  Zaw Zaw Htike,et al.  A Monocular View-Invariant Fall Detection System for the Elderly in Assisted Home Environments , 2011, 2011 Seventh International Conference on Intelligent Environments.

[22]  M. Giger,et al.  Computerized Detection of Pulmonary Nodules in Computed Tomography Images , 1994, Investigative radiology.