t 4 Workshop Report * State-ofthe-Art of 3 D Cultures ( Organs-ona-Chip ) in Safety Testing and Pathophysiology

Natalie Alépée 1, Anthony Bahinski 2, Mardas Daneshian , Bart De Wever , Ellen Fritsche 5, Alan Goldberg 6, Jan Hansmann 7, Thomas Hartung 3,6, John Haycock 8, Helena T. Hogberg 6, Lisa Hoelting 9, Jens M. Kelm 10, Suzanne Kadereit 9, Emily McVey 11, Robert Landsiedel 12, Marcel Leist 3,9, Marc Lübberstedt 13, Fozia Noor 14, Christian Pellevoisin 1, Dirk Petersohn 15, Uwe Pfannenbecker 16, Kerstin Reisinger 15, Tzutzuy Ramirez 12, Barbara Rothen-Rutishauser 17, Monika Schäfer-Korting 18, Katrin Zeilinger 13 and Marie-Gabriele Zurich 19,20 l’Oréal R&I, Aulnay, France; Wyss Institute for Biologically Inspired engineering, Harvard University, Boston, USA; Center for Alternatives to Animal testing – europe (CAAt-europe), University of Konstanz, Konstanz, Germany; the Alexandra Association, Monaco; leibniz Research Institute for environmental Medicine, Duesseldorf, Germany; Center for Alternatives to Animal testing (CAAt), Johns Hopkins University, Bloomberg School of Public Health, Baltimore, USA; Department of tissue engineering and Regenerative Medicine, University Hospital Wuerzburg, Wuerzburg, Germany; Department of Materials Science of Engineering, University of Sheffield, Sheffield, UK; Doerenkamp-Zbinden Chair of in vitro toxicology and Biomedicine, University of Konstanz, Konstanz, Germany; InSphero AG, Schlieren, Switzerland; Board for the Authorization of Plant Protection Products and Biocides, Wageningen, the Netherlands; BASF Se, experimental toxicology and ecology, ludwigshafen, Germany; Bioreactor Group, Berlin-Brandenburg Center for Regenerative therapies (BCRt), Charité Campus Virchow-Klinikum, Berlin, Germany; Biochemical engineering, Saarland University, Saarbruecken, Germany; Henkel AG & Co KGaA, Duesseldorf, Germany; Beiersdorf AG, Hamburg, Germany; Adolphe Merkle Institute, University of Fribourg, Switzerland; Institute for Pharmacy (Pharmacology and toxicology), Freie Universität Berlin, Berlin, Germany; Department of Physiology, Faculty of Biology and Medicine, University of lausanne, lausanne, Switzerland; Swiss Center for Applied Human toxicology (SCAHt), University of lausanne, lausanne, Switzerland

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