Pursuing endogenous high-tech innovation in developing countries: A look at regenerative medicine innovation in Brazil, China and India

Few studies in developing countries have examined innovation in an emerging field such as regenerative medicine (RM). Here, we compare case studies of the RM sectors in Brazil, China and India to help understand RM innovation from a systemic perspective. Innovation in developing countries is usually described as a process of reverse engineering carried out by firms, but we argue that this description is not well suited to innovation in an emerging field such as RM. We show here that innovation in new emerging fields can occur in developing countries by diverse processes not yet discussed in the literature. We introduce the main types of actors in RM innovation, look at the interactions between users and producers, and discuss the advantages and challenges of innovating in RM that are faced by the emerging economies. We find that RM innovation in these countries is demand-driven and occurs under conditions unique to countries with lower-resources. We also find that firms play a smaller role in RM innovation at this stage, showing the importance of considering wider innovation actors in the study of novel innovation dynamics.

[1]  Smita Srinivas,et al.  Developing Countries and Innovation: Searching for a New Analytical Approach , 2008 .

[2]  Hao Xin Scandals Shake Chinese Science , 2006, Science.

[3]  Keun Lee,et al.  Technological Regimes, Catching-Up and Leapfrogging: Findings from the Korean Industries , 2001 .

[4]  Douglas K. Martin,et al.  Introduction: promoting global health through biotechnology , 2004, Nature Biotechnology.

[5]  Luc Soete,et al.  Catching up in technology: entry barriers and windows of opportunity , 1988 .

[6]  A. Daar,et al.  Regenerative medicine in Brazil: small but innovative. , 2010, Regenerative medicine.

[7]  Zong-Tae Bae,et al.  Technology development processes: A model for a developing country with a global perspective , 1988 .

[8]  Halla Thorsteinsdóttir,et al.  The Role of the Health System in Health Biotechnology in Developing Countries , 2007, Technol. Anal. Strateg. Manag..

[9]  Jerry M. Guo,et al.  Splicing Out the West? , 2006, Science.

[10]  L. Kim Building technological capability for industrialization: analytical frameworks and Korea's experience , 1999 .

[11]  A. Daar,et al.  Harnessing stem cells for health needs in India. , 2008, Cell stem cell.

[12]  Linsu Kim,et al.  Technology policies and strategies for developing countries: lessons from the Korean experience , 1998 .

[13]  D. Ernst,et al.  Technological capabilities in the context of export-led growth: a conceptual framework , 2003 .

[14]  D. Cyranoski FDA challenges stem-cell clinic , 2010, Nature.

[15]  Douglas K. Martin,et al.  Regenerative Medicine and the Developing World , 2006, PLoS medicine.

[16]  John Bessant,et al.  Approaching the innovation frontier in Korea: the transition phase to leadership , 2004 .

[17]  Lynn K. Mytelka,et al.  Divides and rules: the impact of new wave technologies on learning and innovation in the South† , 2006 .

[18]  H. Thorsteinsdóttir,et al.  Developing biomedical innovation capacity in India , 2011 .

[19]  S. Lemon,et al.  IMPLICATIONS FOR DEVELOPING COUNTRIES , 2004 .

[20]  Jan Vang,et al.  Innovation system research and developing countries , 2009 .

[21]  Dieter Ernst,et al.  Global production networks and the changing geography of innovation systems. Implications for developing countries , 2002 .

[22]  Cultivating regenerative medicine innovation in China. , 2010, Regenerative medicine.

[23]  Susan E. Reid,et al.  Biotechnology and Nanotechnology: Science-based Enabling Technologies as Windows of Opportunity for LDCs? , 2007 .

[24]  James M. Utterback,et al.  A dynamic model of process and product innovation , 1975 .

[25]  Carlota Perez,et al.  Technological change and opportunities for development as a moving target , 1999 .

[26]  B. Lundvall Dynamics of Industry and Innovation: Organizations, Networks and Systems National Innovation Systems -analytical Concept and Development Tool National Innovation Systems -analytical Concept and Development Tool National Innovation Systems -analytical Concept and Development Tool , 2022 .

[27]  S. Mani,et al.  Sectoral systems of innovation and production in developing countries: an introduction , 2009 .

[28]  Abdallah S. Daar,et al.  Regenerative medicine: New opportunities for developing countries , 2006 .

[29]  T. Macdonald Preventing Chronic Diseases: A Vital Investment , 2006 .

[30]  Franco Malerba,et al.  Sectoral systems of innovation and production in developing countries : actors, structure and evolution , 2009 .