Synaptic function is impaired but not eliminated in C. elegans mutants lacking synaptotagmin

[1]  H. Horvitz,et al.  The GABAergic nervous system of Caenorhabditis elegans , 1993, Nature.

[2]  H. Horvitz,et al.  Genes required for GABA function in Caenorhabditis elegans , 1993, Nature.

[3]  T. Schwarz,et al.  Synaptic transmission persists in synaptotagmin mutants of Drosophila , 1993, Cell.

[4]  K. Kaibuchi,et al.  Rabphilin-3A, a putative target protein for smg p25A/rab3A p25 small GTP-binding protein related to synaptotagmin , 1993, Molecular and cellular biology.

[5]  L. Avery,et al.  The genetics of feeding in Caenorhabditis elegans. , 1993, Genetics.

[6]  R. Kelly Storage and release of neurotransmitters , 1993, Cell.

[7]  R. Zucker,et al.  Multiple calcium-dependent processes related to secretion in bovine chromaffin cells , 1993, Neuron.

[8]  R. Scheller,et al.  A role for synaptotagmin (p65) in regulated exocytosis , 1993, Cell.

[9]  R. Scheller,et al.  Syntaxin: a synaptic protein implicated in docking of synaptic vesicles at presynaptic active zones. , 1992, Science.

[10]  T. Südhof,et al.  Neurexins: synaptic cell surface proteins related to the alpha-latrotoxin receptor and laminin. , 1992, Science.

[11]  A. Ogura,et al.  Neurotransmitter Release from Synaptotagmin-Deficient Clonal Variants of PC 12 Cells , 1992, Science.

[12]  T. Südhof,et al.  Synaptotagmin: a calcium sensor on the synaptic vesicle surface. , 1992, Science.

[13]  C. Lévêque,et al.  The synaptic vesicle protein synaptotagmin associates with calcium channels and is a putative Lambert-Eaton myasthenic syndrome antigen. , 1992, Proceedings of the National Academy of Sciences of the United States of America.

[14]  Robert H. Chow,et al.  Delay in vesicle fusion revealed by electrochemical monitoring of single secretory events in adrenal chromaffin cells , 1992, Nature.

[15]  C. Li,et al.  Localization of FMRF amide‐like peptides in Caenorhabditis elegans , 1992, The Journal of comparative neurology.

[16]  H. Horvitz,et al.  Genes necessary for directed axonal elongation or fasciculation in C. elegans , 1992, Neuron.

[17]  R. Scheller,et al.  Synaptic vesicle membrane proteins interact to form a multimeric complex , 1992, The Journal of cell biology.

[18]  V. Ambros,et al.  Efficient gene transfer in C.elegans: extrachromosomal maintenance and integration of transforming sequences. , 1991, The EMBO journal.

[19]  D. Apps,et al.  Glycosylation and transmembrane topography of bovine chromaffin granule p65. , 1991, The Biochemical journal.

[20]  Thomas C. Südhof,et al.  Binding of synaptotagmin to the α-latrotoxin receptor implicates both in synaptic vesicle exocytosis , 1991, Nature.

[21]  T. Südhof,et al.  Synaptotagmin II. A novel differentially distributed form of synaptotagmin. , 1991, The Journal of biological chemistry.

[22]  R. Hosono,et al.  Additional genes which result in an elevation of acetylcholine levels by mutations in Caenorhabditis elegans , 1991, Neuroscience Letters.

[23]  K. Miller,et al.  Differential expression of the p65 gene family , 1991, Neuron.

[24]  D. Hall,et al.  Kinesin-related gene unc-104 is required for axonal transport of synaptic vesicles in C. elegans , 1991, Cell.

[25]  M. Nonet,et al.  Early aspects of Caenorhabditis elegans sex determination and dosage compensation are regulated by a zinc-finger protein , 1991, Nature.

[26]  Thomas C. Südhof,et al.  Proteins of synaptic vesicles involved in exocytosis and membrane recycling , 1991, Neuron.

[27]  A. Otsuka,et al.  The C. elegans unc-104 4 gene encodes a putative kinesin heavy chain-like protein , 1991, Neuron.

[28]  T. Südhof,et al.  Structural and functional conservation of synaptotagmin (p65) in Drosophila and humans. , 1991, The Journal of biological chemistry.

[29]  T. Südhof,et al.  Domain structure of synaptotagmin (p65) , 1991, The Journal of biological chemistry.

[30]  M Linial,et al.  Cellular and molecular biology of the presynaptic nerve terminal. , 1991, Annual review of neuroscience.

[31]  E. M. Adler,et al.  Strategic location of calcium channels at transmitter release sites of frog neuromuscular synapses , 1990, Neuron.

[32]  Gary Ruvkun,et al.  The unc-86 gene product couples cell lineage and cell identity in C. elegans , 1990, Cell.

[33]  W. Almers,et al.  Transmitter release from synapses: Does a preassembled fusion pore initiate exocytosis? , 1990, Neuron.

[34]  T. Südhof,et al.  Phospholipid binding by a synaptic vesicle protein homologous to the regulatory region of protein kinase C , 1990, Nature.

[35]  H. Horvitz,et al.  Effects of starvation and neuroactive drugs on feeding in Caenorhabditis elegans. , 1990, The Journal of experimental zoology.

[36]  Thomas J. White,et al.  PCR protocols: a guide to methods and applications. , 1990 .

[37]  R. Hosono,et al.  Spontaneous Mutations of Trichlorfon Resistance in the Nematode, Caenorhabditis elegans : Genetics , 1989 .

[38]  J. Rand Genetic analysis of the cha-1-unc-17 gene complex in Caenorhabditis. , 1989, Genetics.

[39]  E. Bamberg,et al.  Identification of synaptophysin as a hexameric channel protein of the synaptic vesicle membrane. , 1988, Science.

[40]  A. Coulson,et al.  Genome linking with yeast artificial chromosomes , 1988, Nature.

[41]  Carl D. Johnson,et al.  The acetylcholinesterase genes of C. elegans: Identification of a third gene (ace-3) and mosaic mapping of a synthetic lethal phenotype , 1988, Neuron.

[42]  R. Tsien,et al.  Dominant role of N-type Ca2+ channels in evoked release of norepinephrine from sympathetic neurons. , 1988, Science.

[43]  J. Fleming,et al.  Cholinergic receptor mutants of the nematode Caenorhabditis elegans , 1987, The Journal of neuroscience : the official journal of the Society for Neuroscience.

[44]  B. Saari,et al.  Activation of a transposable element in the germ line but not the soma of Caenorhabditis elegans , 1987, Nature.

[45]  David Hirsh,et al.  A trans-spliced leader sequence on actin mRNA in C. elegans , 1987, Cell.

[46]  S. Henikoff Unidirectional digestion with exonuclease III in DNA sequence analysis. , 1987, Methods in enzymology.

[47]  T. Gibson,et al.  Lorist6, a cosmid vector with BamHI, NotI, ScaI and HindIII cloning sites and altered neomycin phosphotransferase gene expression. , 1987, Gene.

[48]  S. Brenner,et al.  The structure of the nervous system of the nematode Caenorhabditis elegans. , 1986, Philosophical transactions of the Royal Society of London. Series B, Biological sciences.

[49]  J. Culotti,et al.  Axonal guidance mutants of Caenorhabditis elegans identified by filling sensory neurons with fluorescein dyes. , 1985, Developmental biology.

[50]  Rand Jb,et al.  Molecular basis of drug-resistance mutations in C. elegans. , 1985 .

[51]  R. L. Russell,et al.  Choline acetyltransferase-deficient mutants of the nematode Caenorhabditis elegans. , 1984, Genetics.

[52]  J. Devereux,et al.  A comprehensive set of sequence analysis programs for the VAX , 1984, Nucleic Acids Res..

[53]  L. Reichardt,et al.  Identification of a synaptic vesicle-specific membrane protein with a wide distribution in neuronal and neurosecretory tissue , 1981, The Journal of cell biology.

[54]  A. Mazur,et al.  Ca2+-dependent recycling of synaptic vesicles at the frog neuromuscular junction , 1980, The Journal of cell biology.

[55]  J. Lewis,et al.  Levamisole-resitant mutants of the nematode Caenorhabditis elegans appear to lack pharmacological acetylcholine receptors , 1980, Neuroscience.

[56]  H. Horvitz,et al.  Genetic analysis of Caenorhabditis elegans. , 1980 .

[57]  R. K. Herman,et al.  6 – Genetic Analysis of Caenorhabditis elegans , 1980 .

[58]  S. Brenner,et al.  Nondisjunction Mutants of the Nematode CAENORHABDITIS ELEGANS. , 1979, Genetics.

[59]  R. K. Herman Crossover suppressors and balanced recessive lethals in Caenorhabditis elegans. , 1978, Genetics.

[60]  F. Sanger,et al.  DNA sequencing with chain-terminating inhibitors. , 1977, Proceedings of the National Academy of Sciences of the United States of America.

[61]  R. Mccaman,et al.  Radiochemical assay for ACh: modifications for sub‐picomole measurements , 1977, Journal of neurochemistry.

[62]  S. Brenner The genetics of Caenorhabditis elegans. , 1974, Genetics.