The effect of guanidinylation of PEGylated poly(2-aminoethyl methacrylate) on the systemic delivery of siRNA.

[1]  C. Liu,et al.  An amphiphilic dendrimer for effective delivery of small interfering RNA and gene silencing in vitro and in vivo. , 2012, Angewandte Chemie.

[2]  P. Sun,et al.  An inhalable β₂-adrenoceptor ligand-directed guanidinylated chitosan carrier for targeted delivery of siRNA to lung. , 2012, Journal of controlled release : official journal of the Controlled Release Society.

[3]  Zicai Liang,et al.  Binary and ternary complexes based on polycaprolactone-graft-poly (N, N-dimethylaminoethyl methacrylate) for targeted siRNA delivery. , 2012, Biomaterials.

[4]  Jun Wang,et al.  Targeted Delivery of PLK1-siRNA by ScFv Suppresses Her2+ Breast Cancer Growth and Metastasis , 2012, Science Translational Medicine.

[5]  F. Liu,et al.  Systemic delivery of siRNA via LCP nanoparticle efficiently inhibits lung metastasis. , 2012, Molecular therapy : the journal of the American Society of Gene Therapy.

[6]  Sabrina Pricl,et al.  Efficient delivery of sticky siRNA and potent gene silencing in a prostate cancer model using a generation 5 triethanolamine-core PAMAM dendrimer. , 2012, Molecular pharmaceutics.

[7]  Chun Wang,et al.  Poly(2-aminoethyl methacrylate) with well-defined chain length for DNA vaccine delivery to dendritic cells. , 2011, Biomacromolecules.

[8]  Zicai Liang,et al.  Structural contributions of blocked or grafted poly(2-dimethylaminoethyl methacrylate) on PEGylated polycaprolactone nanoparticles in siRNA delivery. , 2011, Biomaterials.

[9]  Wei Wang,et al.  A laminar flow electroporation system for efficient DNA and siRNA delivery. , 2011, Analytical chemistry.

[10]  M. Rols,et al.  Direct visualization at the single-cell level of siRNA electrotransfer into cancer cells , 2011, Proceedings of the National Academy of Sciences.

[11]  Zhihong Li,et al.  A parylene-based flexible electroporation chip applicable for in vivo gene and siRNA delivery , 2011, 2011 16th International Solid-State Sensors, Actuators and Microsystems Conference.

[12]  Xing-jie Liang,et al.  Ternary complexes of amphiphilic polycaprolactone-graft-poly (N,N-dimethylaminoethyl methacrylate), DNA and polyglutamic acid-graft-poly(ethylene glycol) for gene delivery. , 2011, Biomaterials.

[13]  Wolfgang Kreyling,et al.  Polyethylenimines for RNAi-mediated gene targeting in vivo and siRNA delivery to the lung. , 2011, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

[14]  Gunther Hartmann,et al.  SiRNA delivery with exosome nanoparticles , 2011, Nature Biotechnology.

[15]  Wei Wang,et al.  An efficient and high-throughput electroporation microchip applicable for siRNA delivery. , 2011, Lab on a chip.

[16]  A. Maruyama,et al.  Grafting of poly(ethylene glycol) to poly-lysine augments its lifetime in blood circulation and accumulation in tumors without loss of the ability to associate with siRNA. , 2011, Journal of controlled release : official journal of the Controlled Release Society.

[17]  Paul C. Wang,et al.  Amphiphilic and biodegradable methoxy polyethylene glycol-block-(polycaprolactone-graft-poly(2-(dimethylamino)ethyl methacrylate)) as an effective gene carrier. , 2011, Biomaterials.

[18]  Zicai Liang,et al.  Comprehensive analysis of sequence-specific stability of siRNA. , 2010, FASEB journal : official publication of the Federation of American Societies for Experimental Biology.

[19]  Didier Merlin,et al.  Orally delivered thioketal nanoparticles loaded with TNF-α-siRNA target inflammation and inhibit gene expression in the intestines. , 2010, Nature materials.

[20]  Qiao Jiang,et al.  Enhanced gene delivery and siRNA silencing by gold nanoparticles coated with charge-reversal polyelectrolyte. , 2010, ACS nano.

[21]  Priti Kumar,et al.  Targeted delivery of siRNA to macrophages for anti-inflammatory treatment. , 2010, Molecular therapy : the journal of the American Society of Gene Therapy.

[22]  Mauro Ferrari,et al.  Sustained small interfering RNA delivery by mesoporous silicon particles. , 2010, Cancer research.

[23]  Chun Wang,et al.  Well-defined block copolymers for gene delivery to dendritic cells: probing the effect of polycation chain-length. , 2010, Journal of controlled release : official journal of the Controlled Release Society.

[24]  T. Park,et al.  Co-delivery of siRNA and paclitaxel into cancer cells by biodegradable cationic micelles based on PDMAEMA-PCL-PDMAEMA triblock copolymers. , 2010, Biomaterials.

[25]  Robert Langer,et al.  Knocking down barriers: advances in siRNA delivery , 2009, Nature Reviews Drug Discovery.

[26]  Jinwoo Cheon,et al.  All-in-one target-cell-specific magnetic nanoparticles for simultaneous molecular imaging and siRNA delivery. , 2009, Angewandte Chemie.

[27]  Michael S. Goldberg,et al.  Development of lipidoid-siRNA formulations for systemic delivery to the liver. , 2009, Molecular therapy : the journal of the American Society of Gene Therapy.

[28]  A. Eguchi,et al.  Efficient siRNA Delivery into Primary Cells by Peptide Transduction-dsRNA Binding Domain (PTD-DRBD) Fusion Protein , 2009, Nature Biotechnology.

[29]  C. Cho,et al.  Guanidinylated poly(allyl amine) as a gene carrier , 2009 .

[30]  W. Mark Saltzman,et al.  Intravaginal gene silencing using biodegradable polymer nanoparticles densely loaded with small-interfering RNA , 2009, Nature materials.

[31]  A. Judge,et al.  Confirming the RNAi-mediated mechanism of action of siRNA-based cancer therapeutics in mice. , 2009, The Journal of clinical investigation.

[32]  J. Kjems,et al.  Chitosan/siRNA Nanoparticle-mediated TNF-α Knockdown in Peritoneal Macrophages for Anti-inflammatory Treatment in a Murine Arthritis Model. , 2009, Molecular therapy : the journal of the American Society of Gene Therapy.

[33]  John J Rossi,et al.  Novel dual inhibitory function aptamer-siRNA delivery system for HIV-1 therapy. , 2008, Molecular therapy : the journal of the American Society of Gene Therapy.

[34]  Shuming Nie,et al.  Proton-sponge coated quantum dots for siRNA delivery and intracellular imaging. , 2008, Journal of the American Chemical Society.

[35]  R. Chandra,et al.  Guanidinium-grafted polyethylenimine: an efficient transfecting agent for mammalian cells. , 2008, European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V.

[36]  William H. Heath,et al.  Charged Polymers via Controlled Radical Polymerization and their Implications for Gene Delivery , 2007 .

[37]  Judy Lieberman,et al.  Interfering with disease: a progress report on siRNA-based therapeutics , 2007, Nature Reviews Drug Discovery.

[38]  J Teissié,et al.  In vivo gene silencing in solid tumors by targeted electrically mediated siRNA delivery , 2007, Gene Therapy.

[39]  K. Yao,et al.  Guanidinylated allylamine-N-isopropylacrylamide copolymer nonviral transgene vectors. , 2007, International journal of pharmaceutics.

[40]  Yuan Zhang,et al.  Delivery of Telomerase Reverse Transcriptase Small Interfering RNA in Complex with Positively Charged Single-Walled Carbon Nanotubes Suppresses Tumor Growth , 2006, Clinical Cancer Research.

[41]  Matthias John,et al.  RNAi-mediated gene silencing in non-human primates , 2006, Nature.

[42]  A. Ullrich,et al.  Targeting polo-like kinase 1 for cancer therapy , 2006, Nature Reviews Cancer.

[43]  W. DeGrado,et al.  Amphiphilic polymethacrylate derivatives as antimicrobial agents. , 2005, Journal of the American Chemical Society.

[44]  C. van Nostrum,et al.  Poly(3-guanidinopropyl methacrylate): a novel cationic polymer for gene delivery. , 2004, Bioconjugate chemistry.

[45]  Erich A. Nigg,et al.  Polo-like kinases and the orchestration of cell division , 2004, Nature Reviews Molecular Cell Biology.

[46]  C. Cepko,et al.  Electroporation and RNA interference in the rodent retina in vivo and in vitro , 2003, Proceedings of the National Academy of Sciences of the United States of America.

[47]  Judy Lieberman,et al.  RNA interference targeting Fas protects mice from fulminant hepatitis , 2003, Nature Medicine.

[48]  C. Packard,et al.  Comparison of apolipoprotein B metabolism in familial defective apolipoprotein B and heterogeneous familial hypercholesterolemia. , 2002, Atherosclerosis.

[49]  J. Lehn,et al.  Progress in gene delivery by cationic lipids: guanidinium-cholesterol-based systems as an example. , 2002, Current drug targets.

[50]  K. Pattabiraman,et al.  The design, synthesis, and evaluation of molecules that enable or enhance cellular uptake: peptoid molecular transporters. , 2000, Proceedings of the National Academy of Sciences of the United States of America.

[51]  H. Maeda,et al.  Tumor vascular permeability and the EPR effect in macromolecular therapeutics: a review. , 2000, Journal of controlled release : official journal of the Controlled Release Society.

[52]  J. Wolff,et al.  High levels of foreign gene expression in hepatocytes after tail vein injections of naked plasmid DNA. , 1999, Human gene therapy.

[53]  K. Jankova,et al.  Synthesis of Amphiphilic PS-b-PEG-b-PS by Atom Transfer Radical Polymerization , 1998 .

[54]  M. Relling,et al.  Clinical Pharmacokinetics of Paclitaxel , 1994, Clinical pharmacokinetics.

[55]  R. Sashidhar,et al.  Quantitation of epsilon-amino group using amino acids as reference standards by trinitrobenzene sulfonic acid. A simple spectrophotometric method for the estimation of hapten to carrier protein ratio. , 1994, Journal of immunological methods.