Effect of lateral static load on immediately restored implants: histologic and radiographic evaluation in dogs.

OBJECTIVES The aim of this study was to evaluate the effect of lateral static load in immediately restored implants in the canine mandible. MATERIAL AND METHODS In 7 mongrel dogs, all premolars and the first molars were extracted bilaterally in the mandible. Two months after the extractions, 6 implants with sandblasted acid-etched surfaces were placed in each animal, 3 on each side. Randomly, two implants per side were immediately restored with an orthodontic expansion device that promoted lateral excessive static load (test group) or load (control) while the third implant of each side, remained submerged (unloaded group). These loaded devices were cleaned daily with chlorhexidine 0.12%, during the 4 months of study, when the animals were sacrificed and biopsies removed for histometric study. Intra-oral periapicals were made using positioners at the beginning and at the end of the study. RESULTS Five implants from test group were lost in 3 dogs. Radiographically, there was a marginal bone loss of 3.68 ± 0.74 mm for the test group, 1.63 ± 0.2 mm for the control group and 0.45 ± 0.5 mm for the unloaded group. Histometrically, the percentage of bone-to-implant contact (BIC%) was 35.52 ± 7.32%, for the test group, 63.16 ± 5.16% for the control group and 42.33 ± 2.14% for the unloaded group. CONCLUSION In conclusion, the excessive lateral static load negatively affected the behavior of peri-implant bone around immediate restored implants.

[1]  A. Pozzi,et al.  Clinical and radiological outcomes of two implants with different prosthetic interfaces and neck configurations: randomized, controlled, split-mouth clinical trial. , 2014, Clinical implant dentistry and related research.

[2]  M. Esposito,et al.  Interventions for replacing missing teeth: different times for loading dental implants. , 2013, The Cochrane database of systematic reviews.

[3]  P. Coelho,et al.  Biomechanical evaluation of internal and external hexagon platform switched implant-abutment connections: An in vitro laboratory and three-dimensional finite element analysis. , 2012, Dental materials : official publication of the Academy of Dental Materials.

[4]  Kotaro Oyama,et al.  Biological adaptation to misfits of immediately loaded fixed prostheses following computer-guided surgery. , 2012, Journal of prosthodontics : official journal of the American College of Prosthodontists.

[5]  M. Cullinan,et al.  Immediate placement or immediate restoration/loading of single implants for molar tooth replacement: a systematic review and meta-analysis. , 2010, The International journal of oral & maxillofacial implants.

[6]  A. Piattelli,et al.  Influence of direct laser fabrication implant topography on type IV bone: a histomorphometric study in humans. , 2009, Journal of biomedical materials research. Part A.

[7]  J. Granjeiro,et al.  Basic research methods and current trends of dental implant surfaces. , 2009, Journal of biomedical materials research. Part B, Applied biomaterials.

[8]  J. Shibli,et al.  Composition of supra- and subgingival biofilm of subjects with healthy and diseased implants. , 2008, Clinical oral implants research.

[9]  M. Quirynen,et al.  Impact of local and systemic factors on the incidence of late oral implant loss. , 2008, Clinical oral implants research.

[10]  J. Lindhe,et al.  Bone reactions to longstanding functional load at implants: an experimental study in dogs. , 2005, Journal of clinical periodontology.

[11]  R. Strocchi,et al.  Collagen fiber orientation near dental implants in human bone: do their organization reflect differences in loading? , 2005, Journal of biomedical materials research. Part B, Applied biomaterials.

[12]  I. Naert,et al.  Biologic response of immediately versus delayed loaded implants supporting ill-fitting prostheses: an animal study. , 2005, Clinical implant dentistry and related research.

[13]  C. Misch,et al.  A positive correlation between occlusal trauma and peri-implant bone loss: literature support. , 2005, Implant dentistry.

[14]  N P Lang,et al.  Does excessive occlusal load affect osseointegration? An experimental study in the dog. , 2004, Clinical oral implants research.

[15]  C. Misch,et al.  The causes of early implant bone loss: myth or science? , 2002, Journal of periodontology.

[16]  Marc Quirynen,et al.  Infectious risks for oral implants: a review of the literature. , 2002, Clinical oral implants research.

[17]  J. Lindhe,et al.  Bone reactions adjacent to titanium implants subjected to static load of different duration. A study in the dog (III). , 2001, Clinical oral implants research.

[18]  D Buser,et al.  Crestal bone changes around titanium implants: a methodologic study comparing linear radiographic with histometric measurements. , 2001, The International journal of oral & maxillofacial implants.

[19]  J. Lindhe,et al.  Bone reactions adjacent to titanium implants with different surface characteristics subjected to static load. A study in the dog (II). , 2001, Clinical oral implants research.

[20]  J. Lindhe,et al.  Bone reactions adjacent to titanium implants subjected to static load. A study in the dog (I). , 2001, Clinical oral implants research.

[21]  E. Brunner,et al.  Nonparametric Analysis of Ordered Categorical Data in Designs with Longitudinal Observations and Small Sample Sizes , 2000 .

[22]  J. Hirsch,et al.  Biological factors contributing to failures of osseointegrated oral implants. (II). Etiopathogenesis. , 1998, European journal of oral sciences.

[23]  Kitetsu Shin,et al.  The influence of controlled occlusal overload on peri-implant tissue. part 4: a histologic study in monkeys. , 1998, The International journal of oral & maxillofacial implants.

[24]  A. Scarano,et al.  High-precision, cost-effective cutting system for producing thin sections of oral tissues containing dental implants. , 1997, Biomaterials.

[25]  F. Isidor,et al.  Histological evaluation of peri-implant bone at implants subjected to occlusal overload or plaque accumulation. , 1997, Clinical oral implants research.

[26]  F. Isidor,et al.  Loss of osseointegration caused by occlusal load of oral implants. A clinical and radiographic study in monkeys. , 1996, Clinical oral implants research.

[27]  I. Naert,et al.  Animal experimental findings on the effect of mechanical load on peri-implant tissue differentiation and adaptation , 2012 .

[28]  F. Burny.  [Mechanical properties of bone tissue]. , 1975, Acta orthopaedica Belgica.