Prophylactic administration of avotermin for improvement of skin scarring: three double-blind, placebo-controlled, phase I/II studies

[1]  J. Creasey,et al.  The stretched scar: a clinical and histological study. , 1978, British journal of plastic surgery.

[2]  M. Ferguson,et al.  Immunohistochemical localization of growth factors in fetal wound healing. , 1991, Developmental biology.

[3]  D. Foreman,et al.  Control of scarring in adult wounds by neutralising antibody to transforming growth factor β , 1992, The Lancet.

[4]  D. Foreman,et al.  Neutralising antibody to TGF-beta 1,2 reduces cutaneous scarring in adult rodents. , 1994, Journal of cell science.

[5]  D. Foreman,et al.  Neutralisation of TGF-beta 1 and TGF-beta 2 or exogenous addition of TGF-beta 3 to cutaneous rat wounds reduces scarring. , 1995, Journal of cell science.

[6]  M. Horan,et al.  The effects of ageing on cutaneous wound healing in mammals. , 1995, Journal of anatomy.

[7]  M. Horan,et al.  Aging is associated with reduced deposition of specific extracellular matrix components, an upregulation of angiogenesis, and an altered inflammatory response in a murine incisional wound healing model. , 1997, The Journal of investigative dermatology.

[8]  S. O'Kane,et al.  Transforming growth factor βs and wound healing , 1997 .

[9]  M. Horan,et al.  Aging alters the inflammatory and endothelial cell adhesion molecule profiles during human cutaneous wound healing. , 1998, Laboratory investigation; a journal of technical methods and pathology.

[10]  A. Singer,et al.  Cutaneous wound healing. , 1999, The New England journal of medicine.

[11]  A. Bayat,et al.  Genetic susceptibility to keloid disease: Transforming growth factor β receptor gene polymorphisms are not associated with keloid disease , 2004, Experimental dermatology.

[12]  S. O'Kane,et al.  Scar-free healing: from embryonic mechanisms to adult therapeutic intervention. , 2004, Philosophical transactions of the Royal Society of London. Series B, Biological sciences.

[13]  F. Wood,et al.  [International clinical recommendations on scar management]. , 2002, Zentralblatt fur Chirurgie.

[14]  Jeremy S. Bond,et al.  Visual Analogue Scale Scoring and Ranking: A Suitable and Sensitive Method for Assessing Scar Quality? , 2006, Plastic and reconstructive surgery.

[15]  L. Nanney,et al.  Emerging new drugs for scar reduction , 2006, Expert opinion on emerging drugs.

[16]  Jeremy S. Bond,et al.  Scar Redness in Humans: How Long Does It Persist after Incisional and Excisional Wounding? , 2008, Plastic and reconstructive surgery.