Mitochondrial diabetes is associated with insulin resistance in subcutaneous adipose tissue but not with increased liver fat content
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T. Lehtimäki | P. Iozzo | N. Mononen | K. Majamaa | P. Nuutila | R. Borra | L. Guiducci | K. Virtanen | V. Lepomäki | M. Lindroos
[1] H. Lamb,et al. Liver Fat Content in Type 2 Diabetes: Relationship With Hepatic Perfusion and Substrate Metabolism , 2010, Diabetes.
[2] S. Dimauro,et al. A novel POLG gene mutation in 4 children with Alpers-like hepatocerebral syndromes. , 2010, Archives of neurology.
[3] Ping-Chih Ho,et al. A negative regulatory pathway of GLUT4 trafficking in adipocyte: new function of RIP140 in the cytoplasm via AS160 , 2009, Cell metabolism.
[4] H. Gin,et al. The clinical variability of maternally inherited diabetes and deafness is associated with the degree of heteroplasmy in blood leukocytes. , 2009, The Journal of clinical endocrinology and metabolism.
[5] P. Iozzo,et al. m.3243A>G Mutation in Mitochondrial DNA Leads to Decreased Insulin Sensitivity in Skeletal Muscle and to Progressive β-Cell Dysfunction , 2009, Diabetes.
[6] Leif Groop,et al. Impaired Mitochondrial Function and Insulin Resistance of Skeletal Muscle in Mitochondrial Diabetes , 2009, Diabetes Care.
[7] T. Lehtimäki,et al. Effects of weight loss on visceral and abdominal subcutaneous adipose tissue blood-flow and insulin-mediated glucose uptake in healthy obese subjects , 2009, Annals of medicine.
[8] M. Czech,et al. Paradoxical Effect of Mitochondrial Respiratory Chain Impairment on Insulin Signaling and Glucose Transport in Adipose Cells* , 2008, Journal of Biological Chemistry.
[9] P. Iozzo,et al. Inverse association between liver fat content and hepatic glucose uptake in patients with type 2 diabetes mellitus. , 2008, Metabolism: clinical and experimental.
[10] B. S. Mohammed,et al. Liver, muscle, and adipose tissue insulin action is directly related to intrahepatic triglyceride content in obese subjects. , 2008, Gastroenterology.
[11] Leena Peltonen,et al. Global Transcript Profiles of Fat in Monozygotic Twins Discordant for BMI: Pathways behind Acquired Obesity , 2008, PLoS medicine.
[12] A. Kotronen,et al. Fatty Liver: A Novel Component of the Metabolic Syndrome , 2007, Arteriosclerosis, thrombosis, and vascular biology.
[13] P. Bénit,et al. Targeted Deletion of AIF Decreases Mitochondrial Oxidative Phosphorylation and Protects from Obesity and Diabetes , 2007, Cell.
[14] P. Iozzo,et al. Quantification of liver glucose metabolism by positron emission tomography: validation study in pigs. , 2007, Gastroenterology.
[15] M. Schwartz,et al. Muscle phenotype and mutation load in 51 persons with the 3243A>G mitochondrial DNA mutation. , 2006, Archives of neurology.
[16] H. Westerblad,et al. Respiratory chain dysfunction in skeletal muscle does not cause insulin resistance. , 2006, Biochemical and biophysical research communications.
[17] Kohjiro Ueki,et al. Adiponectin and adiponectin receptors in insulin resistance, diabetes, and the metabolic syndrome. , 2006, The Journal of clinical investigation.
[18] P. Iozzo,et al. 18F-FDG assessment of glucose disposal and production rates during fasting and insulin stimulation: a validation study. , 2006, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.
[19] P. Scifo,et al. Reduced intrahepatic fat content is associated with increased whole-body lipid oxidation in patients with type 1 diabetes , 2005, Diabetologia.
[20] K. Kotani,et al. Adipose-specific overexpression of GLUT4 reverses insulin resistance and diabetes in mice lacking GLUT4 selectively in muscle. , 2005, American journal of physiology. Endocrinology and metabolism.
[21] R. Huupponen,et al. Increased fat mass compensates for insulin resistance in abdominal obesity and type 2 diabetes: a positron-emitting tomography study. , 2005, Diabetes.
[22] S. Grundy,et al. Magnetic resonance spectroscopy to measure hepatic triglyceride content: prevalence of hepatic steatosis in the general population. , 2005, American journal of physiology. Endocrinology and metabolism.
[23] E. Ravussin,et al. Failure of fat cell proliferation, mitochondrial function and fat oxidation results in ectopic fat storage, insulin resistance and type II diabetes mellitus , 2004, International Journal of Obesity.
[24] G. Nijpels,et al. Mitochondrial diabetes: molecular mechanisms and clinical presentation. , 2004, Diabetes.
[25] M. Danna,et al. Insulin resistance, intramyocellular lipid content, and plasma adiponectin in patients with type 1 diabetes. , 2003, American journal of physiology. Endocrinology and metabolism.
[26] P. Iozzo,et al. Effects of metformin and rosiglitazone monotherapy on insulin-mediated hepatic glucose uptake and their relation to visceral fat in type 2 diabetes. , 2003, Diabetes care.
[27] P. Iozzo,et al. Insulin-mediated hepatic glucose uptake is impaired in type 2 diabetes: evidence for a relationship with glycemic control. , 2003, The Journal of clinical endocrinology and metabolism.
[28] Juhani Knuuti,et al. Insulin stimulates liver glucose uptake in humans: an 18F-FDG PET Study. , 2003, Journal of nuclear medicine : official publication, Society of Nuclear Medicine.
[29] John Wilding,et al. Obesity and Diabetes , 2010, Experimental and Clinical Endocrinology & Diabetes.
[30] T. Funahashi,et al. Circulating concentration of adiponectin and its expression in subcutaneous adipose tissue in patients with highly active antiretroviral therapy-associated lipodystrophy. , 2003, The Journal of clinical endocrinology and metabolism.
[31] R. Huupponen,et al. Human adipose tissue glucose uptake determined using [18F]-fluoro-deoxy-glucose ([18F]FDG) and PET in combination with microdialysis , 2001, Diabetologia.
[32] P. Reiss,et al. Lipodystrophy in HIV-1-positive patients is associated with insulin resistance in multiple metabolic pathways , 2001, AIDS.
[33] P. Arner,et al. Rates of skeletal muscle and adipose tissue glycerol release in nonobese and obese subjects. , 2000, Diabetes.
[34] K. Majamaa,et al. Epidemiology of A3243G, the mutation for mitochondrial encephalomyopathy, lactic acidosis, and strokelike episodes: prevalence of the mutation in an adult population. , 1998, American journal of human genetics.
[35] R M Peshock,et al. Prediction of total subcutaneous abdominal, intraperitoneal, and retroperitoneal adipose tissue masses in men by a single axial magnetic resonance imaging slice. , 1997, The American journal of clinical nutrition.
[36] S. Kalhan,et al. Hepatic insulin action in adolescents with insulin-dependent diabetes mellitus: relationship with long-term glycemic control. , 1993, Metabolism: clinical and experimental.
[37] R. Sokol,et al. Liver involvement in Alpers disease. , 1991, The Journal of pediatrics.