Targeted removal of macrophage-secreted interleukin-1 receptor antagonist protects against lethal Candida albicans sepsis.
暂无分享,去创建一个
R. Bruggmann | C. Gabay | J. Galván | J. Baumgartner | H. Probst | S. Freigang | V. Genitsch | C. Cardozo | Sabrina Walthert | Sabine Muth | Geert van Geest | Hang Thi Thuy Gander-Bui | Joëlle Schläfli | Cristina Graham Martinez | Mona Grans | S. Muth | Johanna Baumgartner
[1] Robert L. Goldstone,et al. Microbe capture by splenic macrophages triggers sepsis via T cell-death-dependent neutrophil lifespan shortening , 2022, Nature Communications.
[2] L. Broderick,et al. IL-1 and autoinflammatory disease: biology, pathogenesis and therapeutic targeting , 2022, Nature Reviews Rheumatology.
[3] K. Roemer,et al. Autoantibodies against interleukin-1 receptor antagonist in multisystem inflammatory syndrome in children: a multicentre, retrospective, cohort study , 2022, The Lancet Rheumatology.
[4] M. Netea,et al. Effect of anakinra on mortality in patients with COVID-19: a systematic review and patient-level meta-analysis , 2021, The Lancet Rheumatology.
[5] W. Schaffner,et al. The landscape of candidemia during the COVID-19 pandemic. , 2021, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.
[6] J. Stone,et al. Neutralizing Anti-Interleukin-1 Receptor-Antagonist Autoantibodies Induce Inflammatory and Fibrotic Mediators in IgG4-Related Disease. , 2021, The Journal of allergy and clinical immunology.
[7] I. Mellman,et al. IL-1 and IL-1ra are key regulators of the inflammatory response to RNA vaccines , 2022, Nature Immunology.
[8] R. Medzhitov,et al. Tissue Homeostasis and Inflammation. , 2021, Annual review of immunology.
[9] James S Griffiths,et al. Role for IL-1 Family Cytokines in Fungal Infections , 2021, Frontiers in Microbiology.
[10] A. Puel. Human inborn errors of immunity underlying superficial or invasive candidiasis , 2020, Human Genetics.
[11] C. Gabay,et al. Intracellular IL-1 Receptor Antagonist Isoform 1 Released from Keratinocytes upon Cell Death Acts as an Inhibitor for the Alarmin IL-1α , 2020, The Journal of Immunology.
[12] L. Chatenoud,et al. Chronic Disseminated Candidiasis During Hematological Maligancies: An Immune Reconstitution Inflammatory Syndrome with Expansion of Pathogen-Specific TH1 T Cells. , 2019, The Journal of infectious diseases.
[13] S. Matalon,et al. IL-1RA regulates immunopathogenesis during fungal-associated allergic airway inflammation. , 2019, JCI insight.
[14] K. Schroder,et al. Inflammasome signaling and regulation of interleukin-1 family cytokines , 2019, The Journal of experimental medicine.
[15] N. Mukaida,et al. Type I interferon-driven susceptibility to Mycobacterium tuberculosis is mediated by interleukin-1 receptor antagonist IL-1Ra , 2019, Nature Microbiology.
[16] C. Garlanda,et al. Interleukin-1 and Related Cytokines in the Regulation of Inflammation and Immunity. , 2019, Immunity.
[17] D. Kontoyiannis,et al. Invasive fungal disease and cytomegalovirus infection: is there an association? , 2018, Current opinion in infectious diseases.
[18] L. Chatenoud,et al. Understanding Pathogenesis and Care Challenges of Immune Reconstitution Inflammatory Syndrome in Fungal Infections , 2018, Journal of fungi.
[19] M. Lionakis,et al. The Role of Neutrophils in Host Defense Against Invasive Fungal Infections , 2018, Current Clinical Microbiology Reports.
[20] B. Kullberg,et al. Invasive Candidiasis. , 2019, The New England journal of medicine.
[21] M. Lionakis,et al. Host Control of Fungal Infections: Lessons from Basic Studies and Human Cohorts. , 2018, Annual review of immunology.
[22] N. Reich,et al. Pathogenic Effects of IFIT2 and Interferon-β during Fatal Systemic Candida albicans Infection , 2018, mBio.
[23] M. Donath,et al. β Cell-Specific Deletion of the IL-1 Receptor Antagonist Impairs β Cell Proliferation and Insulin Secretion. , 2018, Cell reports.
[24] C. Ardavı́n,et al. Inflammatory Ly6Chigh Monocytes Protect against Candidiasis through IL‐15‐Driven NK Cell/Neutrophil Activation , 2017, Immunity.
[25] M. Netea,et al. The immunopathology of sepsis and potential therapeutic targets , 2017, Nature Reviews Immunology.
[26] A. Warnatsch,et al. Reactive Oxygen Species Localization Programs Inflammation to Clear Microbes of Different Size , 2017, Immunity.
[27] G. Núñez,et al. Mechanism and Regulation of NLRP3 Inflammasome Activation. , 2016, Trends in biochemical sciences.
[28] Xiaodi Wu,et al. Mafb lineage tracing to distinguish macrophages from other immune lineages reveals dual identity of Langerhans cells , 2016, The Journal of experimental medicine.
[29] V. Dixit,et al. Inflammasomes: mechanism of assembly, regulation and signalling , 2016, Nature Reviews Immunology.
[30] K. Mayer-Barber,et al. Clash of the Cytokine Titans: counter-regulation of interleukin-1 and type I interferon-mediated inflammatory responses , 2016, Cellular & Molecular Immunology.
[31] Mathias Müller,et al. Type I Interferon Signaling Prevents IL-1β-Driven Lethal Systemic Hyperinflammation during Invasive Bacterial Infection of Soft Tissue. , 2016, Cell host & microbe.
[32] R. Bellomo,et al. The Third International Consensus Definitions for Sepsis and Septic Shock (Sepsis-3). , 2016, JAMA.
[33] Richard L. Amdur,et al. Interleukin-1 Receptor Blockade Is Associated With Reduced Mortality in Sepsis Patients With Features of Macrophage Activation Syndrome: Reanalysis of a Prior Phase III Trial* , 2016, Critical care medicine.
[34] C. Gabay,et al. The interleukin (IL)-1 cytokine family--Balance between agonists and antagonists in inflammatory diseases. , 2015, Cytokine.
[35] L. Joosten,et al. Immune defence against Candida fungal infections , 2015, Nature Reviews Immunology.
[36] A. Sher,et al. Type I interferons in infectious disease , 2015, Nature Reviews Immunology.
[37] B. Barker,et al. IL-1α Signaling Is Critical for Leukocyte Recruitment after Pulmonary Aspergillus fumigatus Challenge , 2015, PLoS pathogens.
[38] A. Sher,et al. Host-directed therapy of tuberculosis based on interleukin-1 and type I interferon crosstalk , 2014, Nature.
[39] J. Ruland,et al. Interferon-β production via Dectin-1-Syk-IRF5 signaling in dendritic cells is crucial for immunity to C. albicans. , 2013, Immunity.
[40] E. Latz,et al. Activation and regulation of the inflammasomes , 2013, Nature Reviews Immunology.
[41] Alexander Hoischen,et al. Functional genomics identifies type I interferon pathway as central for host defense against Candida albicans , 2013, Nature Communications.
[42] David W. Denning,et al. Hidden Killers: Human Fungal Infections , 2012, Science Translational Medicine.
[43] K. Kuchler,et al. Type I Interferons Promote Fatal Immunopathology by Regulating Inflammatory Monocytes and Neutrophils during Candida Infections , 2012, PLoS pathogens.
[44] S. Gringhuis,et al. Dectin-1 is an extracellular pathogen sensor for the induction and processing of IL-1β via a noncanonical caspase-8 inflammasome , 2012, Nature Immunology.
[45] Alessandro Costa,et al. Recognition of yeast nucleic acids triggers a host‐protective type I interferon response , 2011, European journal of immunology.
[46] Gordon D. Brown. Innate antifungal immunity: the key role of phagocytes. , 2011, Annual review of immunology.
[47] Pedro Romero,et al. Type I interferon inhibits interleukin-1 production and inflammasome activation. , 2011, Immunity.
[48] C. Gabay,et al. Distinct Roles of Hepatocyte- and Myeloid Cell-Derived IL-1 Receptor Antagonist during Endotoxemia and Sterile Inflammation in Mice , 2010, The Journal of Immunology.
[49] S. Akira,et al. Dectin-2 recognition of alpha-mannans and induction of Th17 cell differentiation is essential for host defense against Candida albicans. , 2010, Immunity.
[50] C. Gabay,et al. Enhanced Th1 and Th17 responses and arthritis severity in mice with a deficiency of myeloid cell-specific interleukin-1 receptor antagonist. , 2010, Arthritis and rheumatism.
[51] P. Gregersen,et al. An autoinflammatory disease with deficiency of the interleukin-1-receptor antagonist. , 2009, The New England journal of medicine.
[52] J. Tschopp,et al. Syk kinase signalling couples to the Nlrp3 inflammasome for anti-fungal host defence , 2009, Nature.
[53] C. Dinarello,et al. Immunological and inflammatory functions of the interleukin-1 family. , 2009, Annual review of immunology.
[54] B. Reizis,et al. Notch–RBP-J signaling controls the homeostasis of CD8− dendritic cells in the spleen , 2007, The Journal of experimental medicine.
[55] J. Ruland,et al. Card9 controls a non-TLR signalling pathway for innate anti-fungal immunity , 2006, Nature.
[56] M. Netea,et al. Endogenous Interleukin (IL)–1α and IL-1β Are Crucial for Host Defense against Disseminated Candidiasis , 2006 .
[57] R. Wenzel,et al. Nosocomial bloodstream infections in US hospitals: analysis of 24,179 cases from a prospective nationwide surveillance study. , 2004, Clinical infectious diseases : an official publication of the Infectious Diseases Society of America.
[58] A. Mantovani,et al. The Contribution of the Toll-Like/IL-1 Receptor Superfamily to Innate and Adaptive Immunity to Fungal Pathogens In Vivo1 , 2004, The Journal of Immunology.
[59] Shankar Srinivas,et al. Cre reporter strains produced by targeted insertion of EYFP and ECFP into the ROSA26 locus , 2001, BMC Developmental Biology.
[60] W. Reith,et al. Conditional gene targeting in macrophages and granulocytes using LysMcre mice , 1999, Transgenic Research.
[61] M. Dorf,et al. Isolation of Mouse Neutrophils , 1997, Current protocols in immunology.
[62] K. Matsushima,et al. Preparation of specific antibodies against murine IL‐1ra and the establishment of IL‐1ra as an endogenous regulator of bacteria‐induced fulminant hepatitis in mice , 1995, Journal of leukocyte biology.
[63] M Aguet,et al. Functional role of type I and type II interferons in antiviral defense. , 1994, Science.
[64] B. Kullberg,et al. Role of granulocytes in increased host resistance to Candida albicans induced by recombinant interleukin-1 , 1990, Infection and immunity.
[65] N. Rooijen,et al. Macrophage Subset Repopulation in the Spleen: Differential Kinetics After Liposome‐Mediated Elimination , 1989, Journal of leukocyte biology.
[66] C. Dinarello,et al. Protection of neutropenic mice from lethal Candida albicans infection by recombinant interleukin 1 , 1988, European journal of immunology.
[67] B. Kullberg,et al. Invasive Candidiasis. , 2015, The New England journal of medicine.
[68] L. Romani. Immunity to fungal infections , 2011, Nature Reviews Immunology.
[69] C. Gabay,et al. Interleukin-1 receptor antagonist: role in biology. , 1998, Annual review of immunology.