Utilization of Cu-nanoparticles as medication agent to reduce atherosclerotic lesions of a bifurcated artery having compliant walls

OBJECTIVE A theoretical analysis is presented to study the bio-nanofluid with copper as medication agent for atherosclerotic bifurcated artery with flexible walls. DESIGN/APPROACH The circulatory framework in human body is comprised of a system of veins that incorporate the bifurcation in this way the impact of copper nanoparticles on parent, at apex and on daughter artery regions (in the wake of being bifurcated) is watched. Streaming of blood along vessel segment is recognized to be newtonian. The consistent idea of the atherosclerotic arterial wall is additionally considered to make relationship with permeability aspects with arterial wall thickness. Copper nanoparticles are utilized to reduce the atherosclertic lesions for bifurcated stenotic artery. FINDINGS The designed equations along with the experimental values of copper nanoparticles and blood are utilized for theoretical investigation. Moreover, hemodynamics impacts are also figure out to examine the flow of blood for atherosclertic artery. Comparison between parent and daughter artery is plotted through velocity profile. To see the theoretical assistance of this copper mediated model in biomedical field, graphical illustration is presented. At the end, noticed that the inclusion of copper nanoparticles enhances the velocity significantly both for parent as well as daughter artery. CONCLUSIONS The circulation of blood is considered to be different from pressure between portions of atherosclerotic and non-atherosclerotic artery. Shear stress is reduces by changing the bifurcation angle for daughter artery while trend is reversed for parent artery. The size of inner circularting bolus decreases by changing compliant parameter for parent artery while shape is changed for daughter artery.

[2]  O. Makinde,et al.  Effects of stenoses on non-Newtonian flow of blood in blood vessels , 2015 .

[3]  S. Nadeem,et al.  Theoretical examination of nanoparticles as a drug carrier with slip effects on the wall of stenosed arteries , 2016 .

[4]  S. Nadeem,et al.  Shape factor and sphericity features examination of Cu and Cu-Al2O3/blood through atherosclerotic artery under the impact of wall characteristic , 2018, Journal of Molecular Liquids.

[5]  D. Schultz,et al.  Modeling of arterial stenosis and its applications to blood diseases. , 2004, Mathematical biosciences.

[6]  T. Salahuddin,et al.  Generalized diffusion effects on Maxwell nanofluid stagnation point flow over a stretchable sheet with slip conditions and chemical reaction , 2019, Journal of the Brazilian Society of Mechanical Sciences and Engineering.

[7]  S. Ijaz,et al.  A Balloon Model Examination with Impulsion of Cu-Nanoparticles as Drug Agent through Stenosed Tapered Elastic Artery , 2017 .

[8]  D. Srinivasacharya,et al.  Computational analysis of magnetic effects on pulsatile flow of couple stress fluid through a bifurcated artery , 2016, Comput. Methods Programs Biomed..

[9]  D. Srinivasacharya,et al.  MHD Effect on the Couple Stress Fluid Flow Through a Bifurcated Artery , 2015 .

[10]  D. F. Young,et al.  Flow characteristics in models of arterial stenoses. I. Steady flow. , 1973, Journal of biomechanics.

[11]  Stephen U. S. Choi Enhancing thermal conductivity of fluids with nano-particles , 1995 .

[12]  S Nadeem,et al.  Numerical simulation of oscillatory oblique stagnation point flow of a magneto micropolar nanofluid , 2019, RSC advances.

[13]  H. Sadaf,et al.  Remarkable Role of Nanoscale Particles and Viscosity Variation in Blood Flow Through Overlapped Atherosclerotic Channel: A Useful Application in Drug Delivery , 2019, Arabian Journal for Science and Engineering.

[14]  Micropolar fluid flow through a stenosed bifurcated artery , 2017 .

[15]  Mohammad Mehdi Rashidi,et al.  An optimal analysis of radiated nanomaterial flow with viscous dissipation and heat source , 2018, Microsystem Technologies.

[16]  T. Hayat,et al.  Mesoscopic investigation for alumina nanofluid heat transfer in permeable medium influenced by Lorentz forces , 2019, Computer Methods in Applied Mechanics and Engineering.

[17]  M. Y. Malik,et al.  Numerical analysis of Carreau fluid flow for generalized Fourier's and Fick's laws , 2019, Applied Numerical Mathematics.

[18]  Noreen Sher Akbar,et al.  Metallic Nanoparticles Analysis for the Peristaltic Flow in an Asymmetric Channel With MHD , 2014, IEEE Transactions on Nanotechnology.

[19]  S. Nadeem,et al.  Investigation of Cu-CuO/blood mediated transportation in stenosed artery with unique features for theoretical outcomes of hemodynamics , 2018 .

[20]  D. Srinivasacharya,et al.  Pulsatile flow of couple stress fluid through a bifurcated artery , 2016, Ain Shams Engineering Journal.

[21]  D. Srinivasacharya,et al.  Mathematical model for blood flow through a bifurcated artery using couple stress fluid. , 2016, Mathematical biosciences.

[22]  D. Srinivasacharya,et al.  Modeling of Blood Flow Through a Bifurcated Artery Using Nanofluid , 2017 .

[23]  Sohail Nadeem,et al.  Investigation of peristaltic flow of Williamson nanofluid in a curved channel with compliant walls , 2014, Applied Nanoscience.

[24]  M. I. Afridi,et al.  Influence of Variable Transport Properties on Nonlinear Radioactive Jeffrey Fluid Flow Over a Disk: Utilization of Generalized Differential Quadrature Method , 2019, Arabian Journal for Science and Engineering.

[25]  M. Y. Malik,et al.  Numerical simulation of electroosmosis regulated peristaltic transport of Bingham nanofluid , 2019, Comput. Methods Programs Biomed..