Endogenous glucose production is inhibited by the adipose-derived protein Acrp30.
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L. Rossetti | P. Scherer | A. Berg | S. Obici | T. Combs | Terry P. Combs | Silvana Obici | Terry P. Combs
[1] P. Scherer,et al. The adipocyte-secreted protein Acrp30 enhances hepatic insulin action , 2001, Nature Medicine.
[2] Y. Terauchi,et al. The fat-derived hormone adiponectin reverses insulin resistance associated with both lipoatrophy and obesity , 2001, Nature Medicine.
[3] G. Shulman,et al. Tissue-specific overexpression of lipoprotein lipase causes tissue-specific insulin resistance , 2001, Proceedings of the National Academy of Sciences of the United States of America.
[4] T. Funahashi,et al. Circulating concentrations of the adipocyte protein adiponectin are decreased in parallel with reduced insulin sensitivity during the progression to type 2 diabetes in rhesus monkeys. , 2001, Diabetes.
[5] T. Funahashi,et al. The Journal of Clinical Endocrinology & Metabolism Printed in U.S.A. Copyright © 2001 by The Endocrine Society Hypoadiponectinemia in Obesity and Type 2 Diabetes: Close Association with Insulin Resistance , 2022 .
[6] H. Lodish,et al. Proteolytic cleavage product of 30-kDa adipocyte complement-related protein increases fatty acid oxidation in muscle and causes weight loss in mice. , 2001, Proceedings of the National Academy of Sciences of the United States of America.
[7] M. Lazar,et al. The hormone resistin links obesity to diabetes , 2001, Nature.
[8] R. Bergman,et al. Central Role of the Adipocyte in the Metabolic Syndrome , 2001, Journal of Investigative Medicine.
[9] M. Reitman,et al. Lipoatrophy Revisited , 2000, Trends in Endocrinology & Metabolism.
[10] C. Dina,et al. Genomewide search for type 2 diabetes-susceptibility genes in French whites: evidence for a novel susceptibility locus for early-onset diabetes on chromosome 3q27-qter and independent replication of a type 2-diabetes locus on chromosome 1q21-q24. , 2000, American journal of human genetics.
[11] L. Chao,et al. Adipose tissue is required for the antidiabetic, but not for the hypolipidemic, effect of thiazolidinediones. , 2000, The Journal of clinical investigation.
[12] J. Olefsky,et al. PPARγ and the Treatment of Insulin Resistance , 2000, Trends in Endocrinology & Metabolism.
[13] J. Flier,et al. In vivo administration of leptin activates signal transduction directly in insulin-sensitive tissues: overlapping but distinct pathways from insulin. , 2000, Endocrinology.
[14] S. Kihara,et al. Genomic structure and mutations in adipose-specific gene, adiponectin , 2000, International Journal of Obesity.
[15] T Nakamura,et al. Plasma concentrations of a novel, adipose-specific protein, adiponectin, in type 2 diabetic patients. , 2000, Arteriosclerosis, thrombosis, and vascular biology.
[16] G. Shulman,et al. Surgical implantation of adipose tissue reverses diabetes in lipoatrophic mice. , 2000, The Journal of clinical investigation.
[17] J. Olefsky,et al. PPAR gamma and the treatment of insulin resistance. , 2000, Trends in endocrinology and metabolism: TEM.
[18] R. Hammer,et al. Leptin reverses insulin resistance and diabetes mellitus in mice with congenital lipodystrophy , 1999, Nature.
[19] T Nakamura,et al. Paradoxical decrease of an adipose-specific protein, adiponectin, in obesity. , 1999, Biochemical and biophysical research communications.
[20] D L Rothman,et al. Effects of free fatty acids on glucose transport and IRS-1-associated phosphatidylinositol 3-kinase activity. , 1999, The Journal of clinical investigation.
[21] J. Després,et al. Obesity and Insulin Resistance , 1999 .
[22] N. Barzilai,et al. Intracerebroventricular Leptin Regulates Hepatic but Not Peripheral Glucose Fluxes* , 1998, The Journal of Biological Chemistry.
[23] C. Burant,et al. Troglitazone action is independent of adipose tissue. , 1997, The Journal of clinical investigation.
[24] G. Cooney,et al. Mechanisms of Liver and Muscle Insulin Resistance Induced by Chronic High-Fat Feeding , 1997, Diabetes.
[25] K. Uysal,et al. Protection from obesity-induced insulin resistance in mice lacking TNF-α function , 1997, Nature.
[26] Wei Chen,et al. Peripheral but not hepatic insulin resistance in mice with one disrupted allele of the glucose transporter type 4 (GLUT4) gene. , 1997, The Journal of clinical investigation.
[27] N. Barzilai,et al. Abnormal regulation of HGP by hyperglycemia in mice with a disrupted glucokinase allele. , 1997, American journal of physiology. Endocrinology and metabolism.
[28] D. Morgan,et al. Effects of leptin on insulin sensitivity in normal rats. , 1997, Endocrinology.
[29] Wei Chen,et al. Role of the glucosamine pathway in fat-induced insulin resistance. , 1997, The Journal of clinical investigation.
[30] C. Chu,et al. The Role of Fatty Acids in Mediating the Effects of Peripheral Insulin on Hepatic Glucose Production in the Conscious Dog , 1997, Diabetes.
[31] G. Boden. Role of Fatty Acids in the Pathogenesis of Insulin Resistance and NIDDM , 1997, Diabetes.
[32] O. Trygstad,et al. Generalized lipodystrophy, congenital and acquired (lipoatrophy) , 1996, Acta paediatrica (Oslo, Norway : 1992). Supplement.
[33] B. Spiegelman,et al. AdipoQ Is a Novel Adipose-specific Gene Dysregulated in Obesity (*) , 1996, The Journal of Biological Chemistry.
[34] N. Barzilai,et al. Quantitation of hepatic glucose fluxes and pathways of hepatic glycogen synthesis in conscious mice. , 1995, The American journal of physiology.
[35] Philipp E. Scherer,et al. A Novel Serum Protein Similar to C1q, Produced Exclusively in Adipocytes (*) , 1995, The Journal of Biological Chemistry.
[36] J. Clore,et al. Loss of hepatic autoregulation after carbohydrate overfeeding in normal man. , 1995, The Journal of clinical investigation.
[37] L. Rossetti,et al. Mechanisms of fatty acid-induced inhibition of glucose uptake. , 1994, The Journal of clinical investigation.
[38] N. Barzilai,et al. Mechanism by which hyperglycemia inhibits hepatic glucose production in conscious rats. Implications for the pathophysiology of fasting hyperglycemia in diabetes. , 1993, The Journal of clinical investigation.
[39] L. Rossetti,et al. Relative contribution of glycogen synthesis and glycolysis to insulin-mediated glucose uptake. A dose-response euglycemic clamp study in normal and diabetic rats. , 1990, The Journal of clinical investigation.