Mitogen-activated Protein Kinase-activated Protein (MAPKAP) Kinase 2 Deficiency Protects Brain from Ischemic Injury in Mice*
暂无分享,去创建一个
M. Gaestel | P. Young | G. Feuerstein | Xinkang Wang | Hugh Wang | Lin Xu
[1] S. DeKosky,et al. The Type 1 Interleukin-1 Receptor Is Essential for the Efficient Activation of Microglia and the Induction of Multiple Proinflammatory Mediators in Response to Brain Injury , 2002, The Journal of Neuroscience.
[2] O. Werz,et al. Arachidonic Acid Promotes Phosphorylation of 5-Lipoxygenase at Ser-271 by MAPK-activated Protein Kinase 2 (MK2)* , 2002, The Journal of Biological Chemistry.
[3] G. Feuerstein,et al. Differential Regulation of IL-1β and TNF-α RNA Expression by MEK1 Inhibitor after Focal Cerebral Ischemia in Mice , 2001 .
[4] G. Feuerstein,et al. Use of Suppression Subtractive Hybridization for Differential Gene Expression in Stroke: Discovery of CD44 Gene Expression and Localization in Permanent Focal Stroke in Rats , 2001, Stroke.
[5] J. Miller,et al. Transient Focal Cerebral Ischemia , 2001 .
[6] S. Kassis,et al. SB 239063, a second-generation p38 mitogen-activated protein kinase inhibitor, reduces brain injury and neurological deficits in cerebral focal ischemia. , 2001, The Journal of pharmacology and experimental therapeutics.
[7] Jun Chen,et al. Programmed Cell Death in Cerebral Ischemia , 2001, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.
[8] N. Rothwell,et al. Interleukin 1 in the brain: biology, pathology and therapeutic target , 2000, Trends in Neurosciences.
[9] K. Nozaki,et al. Activation of Mitogen-Activated Protein Kinases after Transient Forebrain Ischemia in Gerbil Hippocampus , 2000, The Journal of Neuroscience.
[10] A. Reith,et al. Differential activation of MAPK/ERK and p38/SAPK in neurones and glia following focal cerebral ischaemia in the rat. , 2000, Brain research. Molecular brain research.
[11] G. Feuerstein,et al. Role of immune and inflammatory mediators in CNS injury. , 2000, Drug news & perspectives.
[12] R. Currie,et al. Application of real‐time polymerase chain reaction to quantitate induced expression of interleukin‐1β mRNA in ischemic brain tolerance , 2000 .
[13] G. Feuerstein,et al. Inflammation and Stroke: Putative Role for Cytokines, Adhesion Molecules and iNOS in Brain Response to Ischemia , 2000, Brain pathology.
[14] M. Moskowitz,et al. MEK1 protein kinase inhibition protects against damage resulting from focal cerebral ischemia. , 1999, Proceedings of the National Academy of Sciences of the United States of America.
[15] M. Gaestel,et al. MAPKAP kinase 2 is essential for LPS-induced TNF-α biosynthesis , 1999, Nature Cell Biology.
[16] M. Gaestel,et al. Kotlyarov, A. et al. MAPKAP kinase 2 is essential for LPS-induced TNF-alpha biosynthesis. Nat. Cell Biol. 1, 94-97 , 1999 .
[17] Michael Chopp,et al. A rat model of focal embolic cerebral ischemia , 1997, Brain Research.
[18] P. Cohen,et al. Participation of a stress-activated protein kinase cascade in the activation of tyrosine hydroxylase in chromaffin cells. , 1997, European journal of biochemistry.
[19] Steven A. Carr,et al. Pyridinyl Imidazole Inhibitors of p38 Mitogen-activated Protein Kinase Bind in the ATP Site* , 1997, The Journal of Biological Chemistry.
[20] J. Jongstra,et al. LSP1 Is the Major Substrate for Mitogen-activated Protein Kinase-activated Protein Kinase 2 in Human Neutrophils* , 1997, The Journal of Biological Chemistry.
[21] N. Rothwell,et al. Neuroprotective Effects of Human Recombinant Interleukin-1 Receptor Antagonist in Focal Cerebral Ischaemia in the Rat , 1996, Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism.
[22] Michael E. Greenberg,et al. Opposing Effects of ERK and JNK-p38 MAP Kinases on Apoptosis , 1995, Science.
[23] L. Mahadevan,et al. Parallel signal processing among mammalian MAPKs. , 1995, Trends in biochemical sciences.
[24] Jerry L. Adams,et al. A protein kinase involved in the regulation of inflammatory cytokine biosynthesis , 1994, Nature.
[25] Michel Morange,et al. A novel kinase cascade triggered by stress and heat shock that stimulates MAPKAP kinase-2 and phosphorylation of the small heat shock proteins , 1994, Cell.
[26] K Minematsu,et al. Diffusion‐weighted magnetic resonance imaging , 1992, Neurology.
[27] R. Floyd,et al. Free radical damage to protein and DNA: Mechanisms involved and relevant observations on brain undergoing oxidative stress , 1992, Annals of neurology.
[28] R. Lenkinski,et al. Quantitative comparison of magnetic resonance imaging (MRI) and histologic analyses of focal ischemic damage in the rat , 1991, Brain Research Bulletin.
[29] L. Pitts,et al. Evaluation of 2,3,5-triphenyltetrazolium chloride as a stain for detection and quantification of experimental cerebral infarction in rats. , 1986, Stroke.