REGIONAL DIFFERENCES IN THE EPIDEMIOLOGY OF INVASIVE PNEUMOCOCCAL DISEASE IN TODDLERS IN GERMANY

In a population-based study, regional differences in incidence, serotype distribution and resistance rates in invasive pneumococcal disease in 1-2-year-old children were related to different day care attendance rates. Day-care attendance appears to be a relevant risk factor in some German states and should be considered for inclusion in the recommendations for pneumococcal vaccination of children at risk.

[1]  R. Platt,et al.  Community-level predictors of pneumococcal carriage and resistance in young children. , 2004, American journal of epidemiology.

[2]  R. Platt,et al.  Antibiotic-resistant Streptococcus pneumoniae in the heptavalent pneumococcal conjugate vaccine era: predictors of carriage in a multicommunity sample. , 2003, Pediatrics.

[3]  R. von Kries,et al.  Prediction of the potential benefit of different pneumococcal conjugate vaccines on invasive pneumococcal disease in German children , 2002, The Pediatric infectious disease journal.

[4]  J. Md,et al.  Influence of day care attendance on the use of systemic antibiotics in 0- to 2-year-old children. , 2001, Pediatrics.

[5]  C. Deangelis,et al.  Streptococcus pneumoniae carriage in children attending 59 Canadian child care centers. Toronto Child Care Centre Study Group. , 1999, Archives of pediatrics & adolescent medicine.

[6]  P. Nafstad,et al.  Day Care Centers and Respiratory Health , 1999, Pediatrics.

[7]  L. Harrison,et al.  Risk factors for invasive pneumococcal disease in children: a population-based case-control study in North America. , 1999, Pediatrics.

[8]  G. Stefánsdóttir,et al.  Do antimicrobials increase the carriage rate of penicillin resistant pneumococci in children? Cross sectional prevalence study , 1996, BMJ.

[9]  B. Gessner,et al.  Risk factors for invasive disease caused by Streptococcus pneumoniae among Alaska native children younger than two years of age. , 1995, The Pediatric infectious disease journal.

[10]  T. Cherian,et al.  A cluster of invasive pneumococcal disease in young children in child care. , 1994, JAMA.