Metabolome analysis by capillary electrophoresis-mass spectrometry.

Capillary electrophoresis (CE)-mass spectrometry (MS), as an analytical platform, has made significant contributions in advancing metabolomics research, if still limited up to this time. This review, covering reports published between 1998 and 2006, describes how CE-MS has been used thus far in this field, with the majority of the works dealing with targeted metabolite analyses and only a small fraction using it in the comprehensive context. It also discusses how some of the key features of CE-MS were exploited in selected metabolomic applications.

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[91]  Kothandaraman Narasimhan,et al.  Metabolomics and its role in understanding cellular responses in plants , 2005, Plant Cell Reports.

[92]  Masaru Tomita,et al.  Simultaneous determination of the main metabolites in rice leaves using capillary electrophoresis mass spectrometry and capillary electrophoresis diode array detection. , 2004, The Plant journal : for cell and molecular biology.

[93]  Zheng Yang,et al.  Online hyphenated liquid chromatography-nuclear magnetic resonance spectroscopy-mass spectrometry for drug metabolite and nature product analysis. , 2006, Journal of pharmaceutical and biomedical analysis.

[94]  Jianjun Li,et al.  Application of capillary electrophoresis‐ electrospray‐mass spectrometry to the separation and characterization of isomeric lipopolysaccharides of Neisseria meningitidis , 2004, Electrophoresis.

[95]  Walter A. Korfmacher,et al.  High-performance liquid chromatography-atmospheric pressure photoionization/tandem mass spectrometric analysis for small molecules in plasma. , 2003, Analytical chemistry.

[96]  P. Schmitt‐Kopplin,et al.  Evaluation of glycoalkaloids in tubers of genetically modified virus Y-resistant potato plants (var. Désirée) by non-aqueous capillary electrophoresis coupled with electrospray ionization mass spectrometry (NACE–ESI–MS) , 2003, Analytical and bioanalytical chemistry.

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[100]  M. Moini,et al.  Analysis of underivatized amino acids and their D/L-enantiomers by sheathless capillary electrophoresis/electrospray ionization mass spectrometry. , 2003, Analytical chemistry.

[101]  T. Soga,et al.  Amino acid analysis by capillary electrophoresis electrospray ionization mass spectrometry. , 2000, Analytical chemistry.

[102]  Milton L. Lee,et al.  Determination of serotonin and its precursors in human plasma by capillary electrophoresis-electrospray ionization-time-of-flight mass spectrometry. , 2004, Journal of chromatography. B, Analytical technologies in the biomedical and life sciences.

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[104]  Masaru Tomita,et al.  Qualitative and quantitative analysis of amino acids by capillary electrophoresis‐electrospray ionization‐tandem mass spectrometry , 2004, Electrophoresis.

[105]  A. Segura‐Carretero,et al.  Analysis of hop acids and their oxidized derivatives and iso-alpha-acids in beer by capillary electrophoresis-electrospray ionization mass spectrometry. , 2006, Journal of Agricultural and Food Chemistry.