Immunogenicity and protective efficacy of recombinant Leptospira immunoglobulin-like protein B (rLigB) in a hamster challenge model.

[1]  Yung-Fu Chang,et al.  Leptospira immunoglobulin-like protein A variable region (LigAvar) incorporated in liposomes and PLGA microspheres produces a robust immune response correlating to protective immunity. , 2009, Vaccine.

[2]  R. Raman,et al.  Calcium Binds to Leptospiral Immunoglobulin-like Protein, LigB, and Modulates Fibronectin Binding* , 2008, Journal of Biological Chemistry.

[3]  Yung-Fu Chang,et al.  The C-terminal variable domain of LigB from Leptospira mediates binding to fibronectin , 2008, Journal of veterinary science.

[4]  T. de Brito,et al.  Lsa21, a novel leptospiral protein binding adhesive matrix molecules and present during human infection , 2008, BMC Microbiology.

[5]  P. Ho,et al.  In LipL32, the Major Leptospiral Lipoprotein, the C Terminus Is the Primary Immunogenic Domain and Mediates Interaction with Collagen IV and Plasma Fibronectin , 2008, Infection and Immunity.

[6]  S. Egan,et al.  LipL32 Is an Extracellular Matrix-Interacting Protein of Leptospira spp. and Pseudoalteromonas tunicata , 2008, Infection and Immunity.

[7]  Yung-Fu Chang,et al.  Evaluation of protective immunity of Leptospira immunoglobulin like protein A (LigA) DNA vaccine against challenge in hamsters. , 2008, Vaccine.

[8]  G. Cerqueira,et al.  Recombinant Mycobacterium bovis BCG expressing the LipL32 antigen of Leptospira interrogans protects hamsters from challenge. , 2007, Vaccine.

[9]  Hongxuan He,et al.  Immunogenicity of the recombinant leptospiral putative outer membrane proteins as vaccine candidates. , 2007, Vaccine.

[10]  M. Suchard,et al.  Leptospira interrogans Endostatin-Like Outer Membrane Proteins Bind Host Fibronectin, Laminin and Regulators of Complement , 2007, PloS one.

[11]  Yung-Fu Chang,et al.  A domain of the Leptospira LigB contributes to high affinity binding of fibronectin. , 2007, Biochemical and biophysical research communications.

[12]  M. Reis,et al.  The terminal portion of leptospiral immunoglobulin-like protein LigA confers protective immunity against lethal infection in the hamster model of leptospirosis. , 2007, Vaccine.

[13]  V. Wiwanitkit Predicted epitopes of Lig A of Leptospira interrogans by bioinformatics method: a clue for further vaccine development. , 2007, Vaccine.

[14]  Melissa M. Kelley,et al.  Physiological Osmotic Induction of Leptospira interrogans Adhesion: LigA and LigB Bind Extracellular Matrix Proteins and Fibrinogen , 2007, Infection and Immunity.

[15]  A. L. Nascimento,et al.  A Newly Identified Leptospiral Adhesin Mediates Attachment to Laminin , 2006, Infection and Immunity.

[16]  Yung-Fu Chang,et al.  Immunoprotection of Recombinant Leptospiral Immunoglobulin-Like Protein A against Leptospira interrogans Serovar Pomona Infection , 2006, Infection and Immunity.

[17]  B. Chatrenet,et al.  Protection against Leptospira interrogans Sensu Lato Challenge by DNA Immunization with the Gene Encoding Hemolysin-Associated Protein 1 , 2005, Infection and Immunity.

[18]  B. Roe,et al.  Expression of leptospiral immunoglobulin-like protein by Leptospira interrogans and evaluation of its diagnostic potential in a kinetic ELISA. , 2004, Journal of medical microbiology.

[19]  D. Haake,et al.  Outer membrane proteins of pathogenic spirochetes. , 2004, FEMS microbiology reviews.

[20]  Haruo Watanabe,et al.  Leptospiral immunoglobulin-like proteins elicit protective immunity. , 2004, Vaccine.

[21]  M. Willig,et al.  Leptospirosis: a zoonotic disease of global importance. , 2003, The Lancet. Infectious diseases.

[22]  C. Gay,et al.  Comparison of three different leptospiral vaccines for induction of a type 1 immune response to Leptospira borgpetersenii serovar Hardjo. , 2003, Vaccine.

[23]  M. Reis,et al.  Pathogenic Leptospira species express surface‐exposed proteins belonging to the bacterial immunoglobulin superfamily , 2003, Molecular microbiology.

[24]  M. Reis,et al.  Rapid Translocation of Polarized MDCK Cell Monolayers by Leptospira interrogans, an Invasive but Nonintracellular Pathogen , 2002, Infection and Immunity.

[25]  J. Timoney,et al.  Cloning and Molecular Characterization of an Immunogenic LigA Protein of Leptospira interrogans , 2002, Infection and Immunity.

[26]  M. Reis,et al.  Urban epidemic of severe leptospirosis in Brazil , 1999, The Lancet.

[27]  G. Trinchieri,et al.  Interleukin-12 primes human CD4 and CD8 T cell clones for high production of both interferon-gamma and interleukin-10 , 1996, The Journal of experimental medicine.

[28]  Barbara J. Smith,et al.  Prevalence and Serovars of Leptospira Involved in Equine Abortions in Central Kentucky during the 1990 Foaling Season , 1992, Journal of veterinary diagnostic investigation : official publication of the American Association of Veterinary Laboratory Diagnosticians, Inc.

[29]  J. Yu,et al.  A genetic locus of enteropathogenic Escherichia coli necessary for the production of attaching and effacing lesions on tissue culture cells. , 1990, Proceedings of the National Academy of Sciences of the United States of America.

[30]  S. Falkow,et al.  Identification of invasin: A protein that allows enteric bacteria to penetrate cultured mammalian cells , 1987, Cell.