Platelet rich plasma : traitement des tendinopathies chroniques ? Revue de la littérature Platelet rich plasma : treatment of chronic tendinopathies ? Review of literature

Introduction. Some tendinopathies become chronic in spite of an a ppropriate treatment. Further treatment with an inj ection of platelet rich plasma (PRP) can avoid surgical inter vention. Ephemesis. We have made a review of literature concerning the PRP. Its efficacy is due to growth factors containe d in platelets which are from 3 to 50 times more concentrated afte r pr paration than in blood. The use of PRP has goo d results in different medical disciplines and can heal tendons in vitro s udies. However, only one clinical study reports a good efficacy of PRP in the treatment of epicondylitis. Conclusion. PRP is an interesting technique to treat chronic te ndinopathies but there are not enough studies to de termine its real efficacy. Mots clés : platelet-rich plasma ; PRP ; tendinopathies chroniq ues

[1]  G. W. Johnson,et al.  Treatment of lateral epicondylitis. , 1991, The American journal of occupational therapy : official publication of the American Occupational Therapy Association.

[2]  T. Pavelko,et al.  Treatment of Chronic Elbow Tendinosis with Buffered Platelet-Rich Plasma , 2006, The American journal of sports medicine.

[3]  J. Canoso.  The healing power of time: the case of lateral epicondylitis. , 2006, Journal of Rheumatology.

[4]  P. Nurden,et al.  New insights into and novel applications for platelet-rich fibrin therapies. , 2006, Trends in biotechnology.

[5]  S. Lambert,et al.  Ultrasound-guided autologous blood injection for tennis elbow , 2006, Skeletal Radiology.

[6]  T. Zgonis,et al.  Autologous platelet-rich plasma for wound and osseous healing: A review of the literature and commercially available products , 2006, Advances in therapy.

[7]  P. Aspenberg,et al.  How can one platelet injection after tendon injury lead to a stronger tendon after 4 weeks?: Interplay between early regeneration and mechanical stimulation , 2006, Acta orthopaedica.

[8]  B. Boyan,et al.  Platelet-derived growth factor inhibits demineralized bone matrix-induced intramuscular cartilage and bone formation. A study of immunocompromised mice. , 2005, The Journal of bone and joint surgery. American volume.

[9]  P. Nurden,et al.  Autologous preparations rich in growth factors promote proliferation and induce VEGF and HGF production by human tendon cells in culture , 2005, Journal of orthopaedic research : official publication of the Orthopaedic Research Society.

[10]  P. Wehling,et al.  Treatment of muscle injuries by local administration of autologous conditioned serum: a pilot study on sportsmen with muscle strains. , 2004, International journal of sports medicine.

[11]  M. Weiser,et al.  THE HOMEOPATHIC PREPARATION TRAUMEEL® S COMPARED WITH NSAIDS FOR SYMPTOMATIC TREATMENT OF EPICONDYLITIS , 2004 .

[12]  Paquita Nurden,et al.  Autologous platelets as a source of proteins for healing and tissue regeneration , 2003, Thrombosis and Haemostasis.

[13]  J. Karp,et al.  Effect of Platelet Releasate on Bone Cell Migration and Recruitment In Vitro , 2003, The Journal of craniofacial surgery.

[14]  J. Calandruccio,et al.  Autologous blood injections for refractory lateral epicondylitis. , 2003, The Journal of hand surgery.

[15]  G. Murrell,et al.  The Roles of Growth Factors in Tendon and Ligament Healing , 2003, Sports medicine.

[16]  L. Ignarro,et al.  Platelets modulate gastric ulcer healing: Role of endostatin and vascular endothelial growth factor release , 2001, Proceedings of the National Academy of Sciences of the United States of America.

[17]  D. Altchek,et al.  The elbow. , 1997, Clinics in sports medicine.