Porous shape memory polymers: Design and applications

Porous shape memory polymers (SMPs) exhibit geometric and volumetric shape change when actuated by an external stimulus and can be fabricated as foams, scaffolds, meshes, and other polymeric substrates that possess porous three-dimensional macrostructures. These materials have applications in multiple industries such as textiles, biomedical devices, tissue engineering, and aerospace. This review article examines recent developments in porous SMPs, with a focus on fabrication methods, methods of characterization, modes of actuation, and applications. © 2016 Wiley Periodicals, Inc. J. Polym. Sci., Part B: Polym. Phys. 2016, 54, 1300–1318

[1]  H. Meng,et al.  A review of stimuli-responsive shape memory polymer composites , 2013 .

[2]  S. Frerich.  Biopolymer foaming with supercritical CO2—Thermodynamics, foaming behaviour and mechanical characteristics , 2015 .

[3]  N. R. Abdullah,et al.  Determination of Shape Fixity and Shape Recovery Rate of Carbon Nanotube-filled Shape Memory Polymer Nanocomposites , 2012 .

[4]  D. Maitland,et al.  Ultra Low Density and Highly Crosslinked Biocompatible Shape Memory Polyurethane Foams. , 2011, Journal of polymer science. Part B, Polymer physics.

[5]  Qihui Zhou,et al.  Electrospun biomimetic fibrous scaffold from shape memory polymer of PDLLA-co-TMC for bone tissue engineering. , 2014, ACS applied materials & interfaces.

[6]  J. Ortega,et al.  Virtual Treatment of Basilar Aneurysms Using Shape Memory Polymer Foam , 2012, Annals of Biomedical Engineering.

[7]  Byung Kyu Kim,et al.  Study on the Shape Memory Polyamides. Synthesis and Thermomechanical Properties of Polycaprolactone-Polyamide Block Copolymer , 2000 .

[8]  K. J. Lissant,et al.  A study of medium and high internal phase ratio water/polymer emulsions , 1973 .

[9]  W. Huang,et al.  Stimulus-responsive shape memory materials: A review , 2012 .

[10]  A. Lendlein,et al.  Pore-Size Distribution Controls Shape-Memory Properties on the Macro- and Microscale of Polymeric Foams , 2013 .

[11]  S. M. Hasan,et al.  Design and biocompatibility of endovascular aneurysm filling devices. , 2015, Journal of biomedical materials research. Part A.

[12]  L. Yahia,et al.  Shape memory polymer foams for cerebral aneurysm reparation: effects of plasma sterilization on physical properties and cytocompatibility. , 2009, Acta biomaterialia.

[13]  J. Ivens,et al.  Shape recovery in a thermoset shape memory polymer and its fabric-reinforced composites , 2011 .

[14]  Tao Xu,et al.  Durability of shape memory polymer based syntactic foam under accelerated hydrolytic ageing , 2011 .

[15]  Ward Small,et al.  A Shape Memory Polymer Dialysis Needle Adapter for the Reduction of Hemodynamic Stress Within Arteriovenous Grafts , 2006, IEEE Transactions on Biomedical Engineering.

[16]  V. Schmitt,et al.  Tailored Silica Macrocellular Foams: Combining Limited Coalescence‐Based Pickering Emulsion and Sol–Gel Process , 2012 .

[17]  Jon J. Raasch,et al.  Characterization of polyurethane shape memory polymer processed by material extrusion additive manufacturing , 2015 .

[18]  Heng Zhang,et al.  A novel type of shape memory polymer blend and the shape memory mechanism , 2009 .

[19]  Matthew W. Miller,et al.  Opacification of Shape Memory Polymer Foam Designed for Treatment of Intracranial Aneurysms , 2011, Annals of Biomedical Engineering.

[20]  C. R. Nair,et al.  Progress in shape memory epoxy resins , 2013 .

[21]  David J Mooney,et al.  Injectable preformed scaffolds with shape-memory properties , 2012, Proceedings of the National Academy of Sciences.

[22]  B. Keller,et al.  Effects of Isophorone Diisocyanate on the Thermal and Mechanical Properties of Shape-Memory Polyurethane Foams. , 2014, Macromolecular chemistry and physics.

[23]  A. Mikos,et al.  Electrospinning of polymeric nanofibers for tissue engineering applications: a review. , 2006, Tissue engineering.

[24]  N. Annabi,et al.  Fabrication of poly-DL-lactide/polyethylene glycol scaffolds using the gas foaming technique. , 2012, Acta biomaterialia.

[25]  A. Lendlein,et al.  Shape-memory polymers as a technology platform for biomedical applications , 2010, Expert review of medical devices.

[26]  B. Legendre,et al.  Degradation of segmented poly(etherurethane) Tecoflex® induced by electron beam irradiation: Characterization and evaluation , 2001 .

[27]  Jan Feijen,et al.  Porous polymeric structures for tissue engineering prepared by a coagulation, compression moulding and salt leaching technique. , 2003, Biomaterials.

[28]  M. Maugey,et al.  Shape and Temperature Memory of Nanocomposites with Broadened Glass Transition , 2007, Science.

[29]  Jianbin Luo,et al.  Investigation of the film formation mechanism of oil-in-water (O/W) emulsions , 2011 .

[30]  D. McDowell,et al.  Deformation of epoxy shape memory polymer foam. Part I: Experiments and macroscale constitutive modeling , 2010 .

[31]  Xiaofan Luo,et al.  Design strategies for shape memory polymers , 2013 .

[32]  I. Rao,et al.  Constitutive modeling of the mechanics associated with triple shape memory polymers , 2015 .

[33]  Marc Behl,et al.  Triple-shape polymers , 2010 .

[34]  M. Shafaa,et al.  Characterization, and antibacterial properties of novel silver releasing nanocomposite scaffolds fabricated by the gas foaming/salt-leaching technique , 2012 .

[35]  Changyu Shen,et al.  Fabrication and characterization of injection molded poly (ε-caprolactone) and poly (ε-caprolactone)/hydroxyapatite scaffolds for tissue engineering. , 2012, Materials science & engineering. C, Materials for biological applications.

[36]  Farah Ejaz Ahmed,et al.  A review on electrospinning for membrane fabrication: Challenges and applications , 2015 .

[37]  M. Antonietti,et al.  Porous polymers and resins for biotechnological and biomedical applications. , 2002, Journal of biotechnology.

[38]  Keri M Petersen,et al.  A bioactive "self-fitting" shape memory polymer scaffold with potential to treat cranio-maxillo facial bone defects. , 2014, Acta biomaterialia.

[39]  Sung Ho Lee,et al.  Shape memory effects of molded flexible polyurethane foam , 2007 .

[40]  Arnaud Saint-Jalmes,et al.  The science of foaming. , 2015, Advances in colloid and interface science.

[41]  A. Lendlein,et al.  Multifunctional Shape‐Memory Polymers , 2010, Advanced materials.

[42]  Guangming Zhu,et al.  Shape-memory effects of radiation crosslinked poly(ϵ-caprolactone) , 2003 .

[43]  Jonathan S. Colton,et al.  Nucleation of microcellular foam: Theory and practice , 1987 .

[44]  Hani E. Naguib,et al.  Design and characterization of biocompatible shape memory polymer (SMP) blend foams with a dynamic porous structure , 2015 .

[45]  T. Park,et al.  Dexamethasone-releasing biodegradable polymer scaffolds fabricated by a gas-foaming/salt-leaching method. , 2003, Biomaterials.

[46]  A. Eceiza,et al.  Thermally-responsive biopolyurethanes from a biobased diisocyanate , 2015 .

[47]  Quadrini Fabrizio,et al.  Shape memory epoxy foams for space applications , 2012 .

[48]  Q. Meng,et al.  A review of shape memory polymer composites and blends , 2009 .

[49]  W. Benett,et al.  Fabrication and in vitro deployment of a laser-activated shape memory polymer vascular stent , 2007, Biomedical engineering online.

[50]  A. Lendlein,et al.  Shape‐Memory Properties of Polyetherurethane Foams Prepared by Thermally Induced Phase Separation , 2012 .

[51]  Andres F. Arrieta,et al.  Variable stiffness material and structural concepts for morphing applications , 2013 .

[52]  A. Pennings,et al.  Preparation of a polyurethane scaffold for tissue engineering made by a combination of salt leaching and freeze-drying of dioxane , 2006 .

[53]  J. Volckens,et al.  An improved model for particle deposition in porous foams , 2009 .

[54]  V. Schmitt,et al.  Solid-stabilized emulsions , 2008 .

[55]  Rui L. Reis,et al.  Supercritical fluids in biomedical and tissue engineering applications: a review , 2009 .

[56]  Ward Small,et al.  Biomedical applications of thermally activated shape memory polymers. , 2009, Journal of materials chemistry.

[57]  Martin A. M. Gijs,et al.  NOA 63 as a UV-curable material for fabrication of microfluidic channels with native hydrophilicity , 2010 .

[58]  Wei Min Huang,et al.  Thermo-moisture responsive polyurethane shape-memory polymer and composites: a review , 2010 .

[59]  H. Duan,et al.  Electro-active shape memory composites enhanced by flexible carbon nanotube/graphene aerogels , 2015 .

[60]  Andrew Daly,et al.  Shape-memory porous alginate scaffolds for regeneration of the annulus fibrosus: effect of TGF-β3 supplementation and oxygen culture conditions. , 2014, Acta biomaterialia.

[61]  R. M. Baker,et al.  Shape memory poly(ε-caprolactone)-co-poly(ethylene glycol) foams with body temperature triggering and two-way actuation. , 2013, Journal of materials chemistry. B.

[62]  L. Yahia,et al.  Cold hibernated elastic memory foams for endovascular interventions. , 2003, Biomaterials.

[63]  N. R. James,et al.  Polyurethanes with radiopaque properties. , 2006, Biomaterials.

[64]  Mingliang Du,et al.  Synthesis and properties of the vapour-grown carbon nanofiber/epoxy shape memory and conductive foams prepared via latex technology , 2013 .

[65]  Silvia Farè,et al.  Preparation and Characterization of Shape Memory Polymer Scaffolds via Solvent Casting/Particulate Leaching , 2012, Journal of applied biomaterials & functional materials.

[66]  Z. Dang,et al.  Dually actuated triple shape memory polymers of cross-linked polycyclooctene-carbon nanotube/polyethylene nanocomposites. , 2014, ACS applied materials & interfaces.

[67]  Keri M Petersen,et al.  Inorganic-organic shape memory polymer (SMP) foams with highly tunable properties. , 2013, ACS applied materials & interfaces.

[68]  Morvan Ouisse,et al.  Investigations on the frequency and temperature effects on mechanical properties of a shape memory polymer (Veriflex) , 2015 .

[69]  M. Silverstein.  Emulsion-templated porous polymers: A retrospective perspective , 2014 .

[70]  P. Ma,et al.  Strong electroactive biodegradable shape memory polymer networks based on star-shaped polylactide and aniline trimer for bone tissue engineering. , 2015, ACS applied materials & interfaces.

[71]  D. Maitland,et al.  Controlling the Actuation Rate of Low-Density Shape-Memory Polymer Foams in Water. , 2013, Macromolecular chemistry and physics.

[72]  Jikui Luo,et al.  Stability and deterioration of a shape memory polymer fabric composite under thermomechanical stress , 2011 .

[73]  J. Bearinger,et al.  Shape memory polymers based on uniform aliphatic urethane networks , 2007 .

[74]  Chul B. Park,et al.  A Study of the Crystallization, Melting, and Foaming Behaviors of Polylactic Acid in Compressed CO2 , 2009, International journal of molecular sciences.

[75]  Yanju Liu,et al.  Shape-memory polymers and their composites: Stimulus methods and applications , 2011 .

[76]  Martin L. Dunn,et al.  Controlled Sequential Shape Changing Components by 3D Printing of Shape Memory Polymer Multimaterials , 2015 .

[77]  C. Domingo,et al.  Solid-state foaming of biodegradable polyesters by means of supercritical CO2/ethyl lactate mixtures: Towards designing advanced materials by means of sustainable processes , 2014 .

[78]  M. Silverstein,et al.  Shape memory polymer foams from emulsion templating , 2012 .

[79]  M. Marzec,et al.  A review: fabrication of porous polyurethane scaffolds. , 2015, Materials science & engineering. C, Materials for biological applications.

[80]  James H Henderson,et al.  Dynamic cell behavior on shape memory polymer substrates. , 2011, Biomaterials.

[81]  Yong Zhu,et al.  Recent advances in shape–memory polymers: Structure, mechanism, functionality, modeling and applications , 2012 .

[82]  Duncan Maitland,et al.  Laser-activated shape memory polymer intravascular thrombectomy device. , 2005, Optics express.

[83]  Andreas Lendlein,et al.  Temperature‐Memory Polymer Networks with Crystallizable Controlling Units , 2011, Advanced materials.

[84]  Jinlian Hu,et al.  Triple shape memory effect in multiple crystalline polyurethanes , 2010 .

[85]  Jtf Jos Keurentjes,et al.  Sustainable polymer foaming using high pressure carbon dioxide: a review on fundamentals, processes and applications , 2008 .

[86]  Marc Behl,et al.  Biodegradable multiblock copolymers based on oligodepsipeptides with shape-memory properties. , 2009, Macromolecular bioscience.

[87]  U. Schubert,et al.  Shape memory polymers: Past, present and future developments , 2015 .

[88]  Matthew W. Miller,et al.  Reticulation of low density shape memory polymer foam with an in vivo demonstration of vascular occlusion. , 2014, Journal of the mechanical behavior of biomedical materials.

[89]  Dong Wook Kim,et al.  Fabrication of 3D porous silk scaffolds by particulate (salt/sucrose) leaching for bone tissue reconstruction. , 2015, International journal of biological macromolecules.

[90]  K. J. Lissant.  The geometry of high-internal-phase-ratio emulsions , 1966 .

[91]  Thorsten Pretsch,et al.  Designing temperature-memory effects in semicrystalline polyurethane , 2015 .

[92]  Xiabin Jing,et al.  Poly(ε-caprolactone) Polyurethane and Its Shape-Memory Property† , 2005 .

[93]  T. Xie.  Recent advances in polymer shape memory , 2011 .

[94]  David L. McDowell,et al.  Deformation of epoxy shape memory polymer foam: Part II. Mesoscale modeling and simulation , 2010 .

[95]  Masami Okamoto,et al.  Synthetic biopolymer nanocomposites for tissue engineering scaffolds , 2013 .

[96]  Ruggero Bettini,et al.  Solid-state chemistry and particle engineering with supercritical fluids in pharmaceutics. , 2006, European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences.

[97]  Ward Small,et al.  Porous Shape-Memory Polymers , 2013, Polymer reviews.

[98]  Mao Xu,et al.  Polyurethanes having shape memory effects , 1996 .

[99]  Bo Mattiasson,et al.  Polymeric cryogels as promising materials of biotechnological interest. , 2003, Trends in biotechnology.

[100]  L. Yahia,et al.  Medical applications of shape memory polymers , 2007, Biomedical materials.

[101]  Wei Min Huang,et al.  Cooling-/water-responsive shape memory hybrids , 2012 .

[102]  Xiaofan Luo,et al.  Triple‐Shape Polymeric Composites (TSPCs) , 2010 .

[103]  Orawan Suwantong,et al.  Effectual drug-releasing porous scaffolds from 1,6-diisocyanatohexane-extended poly(1,4-butylene succinate) for bone tissue regeneration , 2008 .

[104]  M. Huneault,et al.  Preparation of interconnected poly(ε-caprolactone) porous scaffolds by a combination of polymer and salt particulate leaching , 2006 .

[105]  M. Silverstein.  PolyHIPEs: Recent advances in emulsion-templated porous polymers , 2014 .

[106]  R. D. Venter,et al.  Low density microcellular foam processing in extrusion using CO2 , 1998 .

[107]  R Langer,et al.  Laminated three-dimensional biodegradable foams for use in tissue engineering. , 1993, Biomaterials.

[108]  Thorsten Pretsch,et al.  Triple-shape properties of a thermoresponsive poly(ester urethane) , 2009 .

[109]  H. Qi,et al.  Recent progress in shape memory polymer: New behavior, enabling materials, and mechanistic understanding , 2015 .

[110]  Andreas Lendlein,et al.  Characterization Methods for Shape-Memory Polymers , 2009 .

[111]  J. Mano,et al.  Chitosan/bioactive glass nanoparticles scaffolds with shape memory properties. , 2015, Carbohydrate polymers.

[112]  C. Terkelsen,et al.  Incidence of definite stent thrombosis or in‐stent restenosis after drug‐eluting stent implantation for treatment of coronary in‐stent restenosis: From Western Denmark heart registry , 2013, Catheterization and cardiovascular interventions : official journal of the Society for Cardiac Angiography & Interventions.

[113]  G. Bowlin,et al.  Imaging, Spectroscopic, Mechanical and Biocompatibility Studies of Electrospun Tecoflex® EG 80A Nanofibers and Composites Thereof Containing Multiwalled Carbon Nanotubes. , 2014, Applied surface science.

[114]  B. Kim,et al.  Shape memory polyurethane foams , 2012 .

[115]  M. Kotaki,et al.  A review on polymer nanofibers by electrospinning and their applications in nanocomposites , 2003 .

[116]  Wei Min Huang,et al.  Thermo/moisture responsive shape-memory polymer for possible surgery/operation inside living cells in future , 2010 .

[117]  J. Kasperczyk,et al.  Double layer paclitaxel delivery systems based on bioresorbable terpolymer with shape memory properties. , 2014, International journal of pharmaceutics.

[118]  M. Maskos,et al.  Switchable information carriers based on shape memory polymer , 2012 .

[119]  F. Quadrini,et al.  Shape memory epoxy foams by solid-state foaming , 2010 .

[120]  Wei Min Huang,et al.  Water-driven programmable polyurethane shape memory polymer: Demonstration and mechanism , 2005 .

[121]  Ward Small,et al.  Low density biodegradable shape memory polyurethane foams for embolic biomedical applications. , 2013, Acta biomaterialia.

[122]  C. P. Whitby,et al.  Some general features of limited coalescence in solid-stabilized emulsions , 2003, The European physical journal. E, Soft matter.

[124]  James H Henderson,et al.  Shape-memory-actuated change in scaffold fiber alignment directs stem cell morphology. , 2013, Acta biomaterialia.

[125]  C. Park,et al.  The Thermoresponsive Shape Memory Characteristics of Polyurethane Foam , 2010 .

[126]  Jinsong Leng,et al.  Shape‐Memory Polymer in Response to Solution , 2008 .

[127]  D. Maitland,et al.  The effect of moisture absorption on the physical properties of polyurethane shape memory polymer foams , 2011, Smart materials & structures.