Inflammatory Pathways in Liver Homeostasis and Liver Injury
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[1] N. Fausto,et al. Rapid DNA binding by nuclear factor kappa B in hepatocytes at the start of liver regeneration. , 1995, Cell growth & differentiation : the molecular biology journal of the American Association for Cancer Research.
[2] G. Tiegs. Cellular and cytokine-mediated mechanisms of inflammation and its modulation in immune-mediated liver injury. , 2007, Zeitschrift fur Gastroenterologie.
[3] C. Trautwein,et al. Release c Cytochrome Alpha-Mediated Apoptosis and Is Required for Tumor Necrosis Factor The Mitochondrial Permeability Transition , 1998 .
[4] David M. Rothwarf,et al. A cytokine-responsive IκB kinase that activates the transcription factor NF-κB , 1997, Nature.
[5] Michael Karin,et al. Positive and Negative Regulation of IκB Kinase Activity Through IKKβ Subunit Phosphorylation , 1999 .
[6] C. Galanos,et al. Lethal toxicity of lipopolysaccharide and tumor necrosis factor in normal and D-galactosamine-treated mice , 1987, The Journal of experimental medicine.
[7] M. Neuman. Apoptosis in Diseases of the Liver , 2001, Critical reviews in clinical laboratory sciences.
[8] R. Sun,et al. The roles of innate immune cells in liver injury and regeneration. , 2007, Cellular & molecular immunology.
[9] D. Goeddel,et al. TNF-R1 Signaling: A Beautiful Pathway , 2002, Science.
[10] S. Korsmeyer,et al. Bid-deficient mice are resistant to Fas-induced hepatocellular apoptosis , 1999, Nature.
[11] S. Forbes,et al. Selective depletion of macrophages reveals distinct, opposing roles during liver injury and repair. , 2005, The Journal of clinical investigation.
[12] Matthias Mann,et al. IKK-1 and IKK-2: Cytokine-Activated IκB Kinases Essential for NF-κB Activation , 1997 .
[13] D. Ferrari,et al. Apoptosis signaling by death receptors. , 1998, European journal of biochemistry.
[14] M. Manns,et al. Tumor necrosis factor α in the pathogenesis of human and murine fulminant hepatic failure , 2000 .
[15] Ebrahim Zandi,et al. Direct Phosphorylation of IκB by IKKα and IKKβ: Discrimination Between Free and NF-κB-Bound Substrate , 1998 .
[16] Y. Sasaguri,et al. Suppression of macrophage infiltration inhibits activation of hepatic stellate cells and liver fibrogenesis in rats. , 2005, Gastroenterology.
[17] T. Deerinck,et al. The IKKβ Subunit of IκB Kinase (IKK) is Essential for Nuclear Factor κB Activation and Prevention of Apoptosis , 1999, The Journal of experimental medicine.
[18] J. Fallowfield,et al. Scar-Associated Macrophages Are a Major Source of Hepatic Matrix Metalloproteinase-13 and Facilitate the Resolution of Murine Hepatic Fibrosis1 , 2007, The Journal of Immunology.
[19] F. Tacke,et al. Migratory fate and differentiation of blood monocyte subsets. , 2006, Immunobiology.
[20] G. McCaughan,et al. The site of primary T cell activation is a determinant of the balance between intrahepatic tolerance and immunity. , 2004, The Journal of clinical investigation.
[21] V. Dixit,et al. Death receptors: signaling and modulation. , 1998, Science.
[22] Michael Karin,et al. NF-κB in cancer: from innocent bystander to major culprit , 2002, Nature Reviews Cancer.
[23] Dongxiao Zhang,et al. STAT3 Participates in Transcriptional Activation of the C-reactive Protein Gene by Interleukin-6 (*) , 1996, The Journal of Biological Chemistry.
[24] M. Manns,et al. Hepatocyte and immune system: acute phase reaction as a contribution to early defence mechanisms. , 1994, Gut.
[25] B. Rehermann,et al. The liver as an immunological organ , 2006, Hepatology.
[26] C. Hogaboam,et al. CCR5 deficiency drives enhanced natural killer cell trafficking to and activation within the liver in murine T cell-mediated hepatitis. , 2007, The American journal of pathology.
[27] Makoto Naito,et al. Development, differentiation, and maturation of Kupffer cells , 1998, Microscopy research and technique.
[28] T. Luedde,et al. Evaluation of the role of nuclear factor‐κB signaling in liver injury using genetic animal models , 2006, Journal of gastroenterology and hepatology.
[29] G Cantarella,et al. Recruitment of the IKK signalosome to the p55 TNF receptor: RIP and A20 bind to NEMO (IKKgamma) upon receptor stimulation. , 2000, Immunity.
[30] T. Mak,et al. Severe liver degeneration and lack of NF-kappaB activation in NEMO/IKKgamma-deficient mice. , 2000, Genes & development.
[31] David Baltimore,et al. An Essential Role for NF-κB in Preventing TNF-α-Induced Cell Death , 1996, Science.
[32] F. Tacke,et al. Monocyte subsets differentially employ CCR2, CCR5, and CX3CR1 to accumulate within atherosclerotic plaques. , 2007, The Journal of clinical investigation.
[33] Seamus J. Martin,et al. Protease activation during apoptosis: Death by a thousand cuts? , 1995, Cell.
[34] T. Luedde,et al. Intracellular survival pathways in the liver , 2006, Liver international : official journal of the International Association for the Study of the Liver.
[35] H. Volk,et al. Tumor necrosis factor-induced apoptosis during the poisoning of mice with hepatotoxins. , 1997, Gastroenterology.
[36] R. Pierce,et al. Kupffer cell heterogeneity: functional properties of bone marrow derived and sessile hepatic macrophages. , 2007, Blood.
[37] Christian Trautwein,et al. Losing balance: cytokine signaling and cell death in the context of hepatocyte injury and hepatic failure. , 2003, European cytokine network.
[38] F. Chisari,et al. Natural Killer T Cell Activation Inhibits Hepatitis B Virus Replication in Vivo , 2000, The Journal of experimental medicine.
[39] Werner Müller,et al. Interleukin 6/gp130‐dependent pathways are protective during chronic liver diseases , 2003, Hepatology.
[40] R. Gaynor,et al. IκB kinases: key regulators of the NF-κB pathway , 2004 .
[41] Mike Rothe,et al. IκB Kinase-β: NF-κB Activation and Complex Formation with IκB Kinase-α and NIK , 1997 .
[42] T. Deerinck,et al. Abnormal Morphogenesis But Intact IKK Activation in Mice Lacking the IKKα Subunit of IκB Kinase , 1999 .
[43] F. Ginhoux,et al. Immature monocytes acquire antigens from other cells in the bone marrow and present them to T cells after maturing in the periphery , 2006, The Journal of experimental medicine.
[44] D. Ho,et al. Recognition of bacterial glycosphingolipids by natural killer T cells , 2005, Nature.
[45] T. Papadopoulos,et al. Importance of Kupffer cells for T-cell-dependent liver injury in mice. , 2000, The American journal of pathology.
[46] P. Knolle. Involvement of the Liver in the Induction of CD8 T Cell Tolerance towards Oral Antigen , 2006, Zeitschrift fur Gastroenterologie.
[47] E. Zandi,et al. The IκB Kinase Complex (IKK) Contains Two Kinase Subunits, IKKα and IKKβ, Necessary for IκB Phosphorylation and NF-κB Activation , 1997, Cell.
[48] Michael Karin,et al. Dissection of TNF Receptor 1 Effector Functions: JNK Activation Is Not Linked to Apoptosis While NF-κB Activation Prevents Cell Death , 1996, Cell.
[49] T. Luedde,et al. Dissection of the NF-κB signalling cascade in transgenic and knockout mice , 2006, Cell Death and Differentiation.
[50] E. Zandi,et al. IKK-γ is an essential regulatory subunit of the IκB kinase complex , 1998, Nature.
[51] M. Leist,et al. Murine hepatocyte apoptosis induced in vitro and in vivo by TNF-alpha requires transcriptional arrest. , 1994, Journal of immunology.
[52] Yulong Zhang,et al. Ischemia/reperfusion injury in the liver of BALB/c mice activates AP‐1 and nuclear factor κB independently of IκB degradation , 1998 .
[53] L. Old,et al. Absence of tumor necrosis factor rescues RelA-deficient mice from embryonic lethality. , 1999, Proceedings of the National Academy of Sciences of the United States of America.
[54] Y. Shiratori,et al. Limitation of combination therapy of interferon and ribavirin for older patients with chronic hepatitis C , 2006, Hepatology.
[55] M. Mann,et al. IκB Kinase (IKK)-Associated Protein 1, a Common Component of the Heterogeneous IKK Complex , 1999, Molecular and Cellular Biology.
[56] S. Akira,et al. Limb and skin abnormalities in mice lacking IKKalpha. , 1999, Science.
[57] R. Gale,et al. Bone marrow origin of hepatic macrophages (Kupffer cells) in humans. , 1978, Science.
[58] P. Borrow,et al. Cytokines induced during chronic hepatitis B virus infection promote a pathway for NK cell–mediated liver damage , 2007, The Journal of experimental medicine.
[59] M J May,et al. NF-kappa B and Rel proteins: evolutionarily conserved mediators of immune responses. , 1998, Annual review of immunology.
[60] D. Goeddel,et al. Identification and Characterization of an IκB Kinase , 1997, Cell.
[61] M. Karin,et al. The α and β Subunits of IκB Kinase (IKK) Mediate TRAF2-Dependent IKK Recruitment to Tumor Necrosis Factor (TNF) Receptor 1 in Response to TNF , 2001, Molecular and Cellular Biology.
[62] T. Luedde,et al. Interleukin 6 and liver regeneration , 2000, Gut.
[63] A. Gerbes,et al. Role of Kupffer cells in host defense and liver disease , 2006, Liver international : official journal of the International Association for the Study of the Liver.
[64] M. Karin. How NF-κB is activated: the role of the IκB kinase (IKK) complex , 1999, Oncogene.
[65] Deletion of IKK2 in hepatocytes does not sensitize these cells to TNF-induced apoptosis but protects from ischemia/reperfusion injury. , 2005, The Journal of clinical investigation.
[66] M. Manns,et al. The IL-6-gp130-STAT3 pathway in hepatocytes triggers liver protection in T cell-mediated liver injury. , 2005, The Journal of clinical investigation.
[67] Exogenous and endogenous glycolipid antigens activate NKT cells during microbial infections , 2005, Nature.
[68] M. Manns,et al. Lack of gp130 expression results in more bacterial infection and higher mortality during chronic cholestasis in mice , 2005, Hepatology.
[69] C. Trautwein,et al. Hepatocyte-Specific IKKγ/NEMO Expression Determines the Degree of Liver Injury , 2007 .
[70] H. Ljunggren,et al. Efficient presentation of exogenous antigen by liver endothelial cells to CD8+ T cells results in antigen-specific T-cell tolerance , 2000, Nature Medicine.
[71] Inder M. Verma,et al. Severe Liver Degeneration in Mice Lacking the IκB Kinase 2 Gene , 1999 .
[72] S. Kaufmann,et al. Ito cells are liver-resident antigen-presenting cells for activating T cell responses. , 2007, Immunity.
[73] B. John,et al. Cellular and molecular mechanisms of liver tolerance , 2006, Immunological reviews.
[74] D. Goeddel,et al. Embryonic Lethality, Liver Degeneration, and Impaired NF-κB Activation in IKK-β-Deficient Mice , 1999 .
[75] M. Kelliher,et al. The distinct roles of TRAF2 and RIP in IKK activation by TNF-R1: TRAF2 recruits IKK to TNF-R1 while RIP mediates IKK activation. , 2000, Immunity.
[76] M. Manns,et al. Lack of gp130 expression in hepatocytes promotes liver injury. , 2003, Gastroenterology.